Accès ouvert
2026
article
OpenAlex
Amrita Mukherjee, Lanfang Xu, Darios Getahun, Jessica Chubak et autres
BACKGROUND: Early-onset colorectal cancer (eoCRC), particularly rectal cancer, is increasing. We evaluated the association between high birth weight and eoCRC in a nested case-control study. METHODS: We included patients aged 15-49 years diagnosed with colorectal adenocarcinoma at Kaiser Permanente Southern California (2009-2021). …
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Accès ouvert
2026
supplementary-materials
OpenAlex
Chun Chao, Lanfang Xu, Bechien U. Wu, Jane C. Figueiredo et autres
Supplemental Table 4. Adjusted odds ratio for antibiotic exposures from 2 to 4.9 years prior to diagnosis/index date among those with ≥15 years of prior membership and those with ≥5 years of prior membership
Accès ouvert
2026
supplementary-materials
OpenAlex
Chun Chao, Lanfang Xu, Bechien U. Wu, Jane C. Figueiredo et autres
Supplemental Table 3. Characteristics of the cases and controls with at least 5 years of prior membership in the sensitivity analysis
Accès ouvert
2026
other
OpenAlex
Chun Chao, Lanfang Xu, Bechien U. Wu, Jane C. Figueiredo et autres
AbstractBackground: Exposure to broad-spectrum antibiotics may alter the risk of early-onset colorectal cancer (eoCRC) via gut dysbiosis. We evaluated the associations between oral broad-spectrum and narrow-spectrum antibiotic use and eoCRC. Methods: We conducted a nested case–control study within Kaiser Permanente Southern California …
Accès ouvert
2026
supplementary-materials
OpenAlex
Chun Chao, Lanfang Xu, Bechien U. Wu, Jane C. Figueiredo et autres
Supplemental Table 1. Classification of antibiotics in the study into broad-spectrum and narrow-spectrum antibiotics
Accès ouvert
2026
supplementary-materials
OpenAlex
Chun Chao, Lanfang Xu, Bechien U. Wu, Jane C. Figueiredo et autres
Supplemental Table 2. Data source for covariates assessed in the study.
Accès ouvert
2026
article
OpenAlex
Bharat Poudel, Zhixin Wang, Daichi Shimbo, Joseph E. Schwartz et autres
Background: Concerns about hypotension and excessive blood pressure (BP) variability leading to falls may be a barrier to achieving BP treatment goals among older adults. Home BP monitoring (HBPM) may allow for better BP management while avoiding falls. Methods: = 541), were …
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2026
article
OpenAlex
Chyke Doubeni, Chun Chao, Christopher D. Jensen, Courtney Burton et autres
2026
article
OpenAlex
Chyke Doubeni, Chun Chao, Christopher D. Jensen, Courtney Burton et autres
2026
conference-abstract
OpenAlex
Chun Chao, Hui Zhou, Cody Ramin, Lanfang Xu et autres
Abstract Introduction: The incidence of second primary cancer (SPC) is on the rise. In the United States, about 20% of all new cancers diagnosed annually are estimated to be SPC. Prior studies of the SEER registries suggested that survival was inferior in …
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Accès ouvert
2026
article
OpenAlex
Keisuke Narita, C. Barrett Bowling, Kimberly L. Cannavale, Chloe Fang et autres
BACKGROUND: Postprandial hypotension (PPH) may contribute to falls among older adults, particularly those taking antihypertensive medication. However, evidence on this association in community-dwelling populations is limited. Since ambulatory blood pressure (BP) monitoring captures BP during daily activities, it may provide accurate assessments …
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Accès ouvert
2026
article
OpenAlex
Daichi Shimbo, C. Barrett Bowling, Kimberly L. Cannavale, Chloe Fang et autres
BACKGROUND: A barrier to intensification of antihypertensive medication among older adults with hypertension is the perceived risk of falls. Blood pressure (BP) measured in the clinic setting is primarily used to decide whether antihypertensive medication should be intensified. Scarce data exist on …
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