Amir Salehi-Najafabadi

Bioactive compounds of the Actinomycetes isolated from Garmsar Saline River, Iran

Ensieh Salehghamari, Maryam Sardabi, Fatemeh Bahrami, Ehsan Fallah Mobarakeh et autres

Abstract Saline environments are unique ecosystems that harbor novel bacterial species with the potential to produce valuable secondary metabolites. In the present study, 26 actinomycetes strains were recovered predominantly from the rhizosphere (81%), in addition to sediments and water samples collected from …

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Insights into additional lactone-based signaling circuits in Streptomyces: existence of acyl-homoserine lactones and LuxI/LuxR homologs in six Streptomyces species

Amir Salehi-Najafabadi, Sepand Tehrani Fateh, Ghassem Amoabediny, Javad Hamedi

Acyl-homoserine lactones (AHLs), mediating pivotal physiological activities through quorum sensing (QS), have conventionally been considered limited to Gram-negative bacteria. However, few reports on the existence of AHLs in Gram-positive bacteria have questioned this conception. Streptomyces, as Gram-positive bacteria already utilizing a lactone-based …

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Protein corona: challenges and opportunities for cancer therapy

Sahand Tehrani Fateh, Fatemeh Mehryab, Sepand Tehrani Fateh, Amir Salehi-Najafabadi et autres

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List of contributors

Ernest C. Agwamba, Samad Ahadian, Fatemeh Maghsood Ahmadi, Roohollah Ahmadian et autres

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Nanomaterials affecting cellular metabolism: opportunities and challenges for cancer therapy

Sepand Tehrani Fateh, Sahand Tehrani Fateh, Amir Salehi-Najafabadi, Amir Reza Aref

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Commercial and regulatory challenges in cancer nanomedicine

Sepand Tehrani Fateh, Sahand Tehrani Fateh, Amir Salehi-Najafabadi, Amir Reza Aref

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Healthy Male Individuals Possess Higher Plasma HER-2 Level than Females.

Sepand Tehrani Fateh, Abbas Behgozin, Farshid Yekani, Lobat Geranpayeh et autres

Considering HER2 as one of the well-known biomarkers in the cancer field, and published articles regarding serum levels of HER2, in this paper we tried to highlight the issue that most studies don't stratify the HER-2 concentration of individuals in terms of …

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Repurposing of substances with lactone moiety for the treatment of γ-Hydroxybutyric acid and γ-Butyrolactone intoxication through modulating paraoxonase and PPARγ

Sepand Tehrani Fateh, Amir Salehi-Najafabadi

GHB and GBL are highly accessible recreational drugs of abuse with a high risk of adverse effects and mortality while no specific antidotes exist. These components can also be found in the clinical setting, beverages, and cosmetic products, leading to unwanted exposures …

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The Effects of Sesquiterpene Lactones on the Differentiation of Human or Animal Cells Cultured In-Vitro: A Critical Systematic Review

Sepand Tehrani Fateh, Sahand Tehrani Fateh, Faezeh Shekari, Majid Mahdavi et autres

Cellular differentiation is pivotal in health and disease. Interfering with the process of differentiation, such as inhibiting the differentiation of adipocytes and inducing the differentiation of cancer cells, is considered a therapeutic approach. Sesquiterpene lactones, primarily found in plants, have been attracted …

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An Update to the Current Passive Immunotherapeutic Approaches to COVID-19 Treatment

Sasan Ghaffari, Hanif Kazerooni, Amir Salehi-Najafabadi

The newest member of the coronavirus family, the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has caused a pandemic (after being endemic in Wuhan, China) and is threatening to the health of every person on the planet. Nearly 1.5 years after the …

Molecular Communications Based on in Vitro Biological Experiments in Terms of Laboratory Data

Alireza amoabedini, Morteza Ebrahimi, Hossein Bobarshad, Amir Salehi-Najafabadi

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The current advances of CRISPR/Cas-based systems for the detection of COVID-19

Sasan Ghaffari, Hanif Kazerooni, Amir Salehi-Najafabadi

The novel coronavirus disease 2019 (COVID-19) still poses a serious threat to every human on the planet nearly 1.5 years after its beginning. Unfortunately, the current diagnostic methods, although highly sensitive and specific, still suffer from many shortcomings. Faster and easy-to-operate diagnostic …

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