Siska Elisahbet Sinaga

Three resorcylic acid lactones from an endophyte, Leptosphaeria sp

Reo Takahashi, 清水幸生, Zulfikar, Mark Anthony Angeles Mangoba et autres

Three new resorcylic acid lactone derivatives, viz., spirolasiodiplodin (1), (3S,4S)-9-oxo-de-O-methyllasiodiplodin (2), and (3S,5R)-9-oxo-de-O-methyllasiodiplodin (3), along with two known compounds, viz., (3S)-dihydroresorcylide (4) and alternariol-2,4-dimethylether (5), were isolated from Leptosphaeria sp. S-55, an endophyte. The structures of these undescribed compounds, including their absolute …

Three resorcylic acid lactones from an endophyte, Leptosphaeria sp

Reo Takahashi, 清水幸生, Zulfikar, Mark Anthony Angeles Mangoba et autres

Three new resorcylic acid lactone derivatives, viz., spirolasiodiplodin (1), (3S,4S)-9-oxo-de-O-methyllasiodiplodin (2), and (3S,5R)-9-oxo-de-O-methyllasiodiplodin (3), along with two known compounds, viz., (3S)-dihydroresorcylide (4) and alternariol-2,4-dimethylether (5), were isolated from Leptosphaeria sp. S-55, an endophyte. The structures of these undescribed compounds, including their absolute …

Three resorcylic acid lactones from an endophyte, Leptosphaeria sp

Reo Takahashi, 清水幸生, Zulfikar, Mark Anthony Angeles Mangoba et autres

Three new resorcylic acid lactone derivatives, viz., spirolasiodiplodin (1), (3S,4S)-9-oxo-de-O-methyllasiodiplodin (2), and (3S,5R)-9-oxo-de-O-methyllasiodiplodin (3), along with two known compounds, viz., (3S)-dihydroresorcylide (4) and alternariol-2,4-dimethylether (5), were isolated from Leptosphaeria sp. S-55, an endophyte. The structures of these undescribed compounds, including their absolute …

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Antioxidant Activity, LC-MS/MS Identification and In Silico Analysis of the Ethanol Extract of Beneng Taro Leaves (Xanthosoma undipes K. Koch) Grown in Three Different Locations

Diana Widiastuti, Rudi Dwi Hariyanto, Siska Elisahbet Sinaga, Wira Eka Putra et autres

Xanthosoma undipes K. Koch (Beneng taro) leaves are rich in bioactive compounds with reported antioxidant and anticancer potential. This study evaluated the antioxidant activity of ethanol extracts from Beneng taro leaves cultivated in three locations, identified active compounds using liquid chromatography–tandem mass …

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A new eudesmane type sesquiterpenoid from the stem bark of Aglaia pachyphylla with cytotoxic and anti-inflammatory activities

Wahyu Safriansyah, Josephine Elizabeth Siregar, Erina Hilmayanti, Siska Elisahbet Sinaga et autres

This study aims to isolate an undescribed eudesmane-type sesquiterpenoid, phyllunone A (1), along with 5 known sesquiterpenoids from n-hexane extract of Aglaia pachyphylla stem bark. The structural elucidation of compound 1 was achieved using NMR, HRMS, ECD, and was further supported by …

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A new eudesmane type sesquiterpenoid from the stem bark of Aglaia pachyphylla with cytotoxic and anti-inflammatory activities

Wahyu Safriansyah, Josephine Elizabeth Siregar, Erina Hilmayanti, Siska Elisahbet Sinaga et autres

This study aims to isolate an undescribed eudesmane-type sesquiterpenoid, phyllunone A (1), along with 5 known sesquiterpenoids from n-hexane extract of Aglaia pachyphylla stem bark. The structural elucidation of compound 1 was achieved using NMR, HRMS, ECD, and was further supported by …

A new eudesmane type sesquiterpenoid from the stem bark of Aglaia pachyphylla with cytotoxic and anti-inflammatory activities

Wahyu Safriansyah, Josephine Elizabeth Siregar, Erina Hilmayanti, Siska Elisahbet Sinaga et autres

This study aims to isolate an undescribed eudesmane-type sesquiterpenoid, phyllunone A (1), along with 5 known sesquiterpenoids from n-hexane extract of Aglaia pachyphylla stem bark. The structural elucidation of compound 1 was achieved using NMR, HRMS, ECD, and was further supported by …

Antioxidant Potential and Active Compound Identification of Hylocereus costaricensis and Hylocereus undatus Peel Extracts using LC-MS/MS

Ade Heri Mulyati, Reni Nurmayani, Diana Widiastuti, Siti Warnasih et autres

The object of this research was to determine the antioxidant potential and identify active compounds in the peel extracts of red dragon fruit (Hylocereus costaricensis) and white dragon fruit (Hylocereus undatus). Phytochemical tests were conducted to identify flavonoids, alkaloids, tannins, coumarins, and …

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Nitrogen-containing secondary metabolites from Meliaceae Family and their biological activity: a review

Ni Wayan Martiningsih, Siska Elisahbet Sinaga, Wahyu Safriansyah, Unang Supratman et autres

The Meliaceae family, widely distributed in tropical and subtropical regions, has been traditionally used for medicinal purposes, particularly in treating infections and inflammatory diseases. The objective of this study is to provide a comprehensive account of the nitrogen-containing secondary metabolites and their …

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Anti-Cholesterol Activity, LC-MS/MS Compound Profiling, and In Silico Analysis of Menteng (Baccaurea racemosa Muell. Arg.) Leaves Extracts

Ade Heri Mulyati, Diana Widiastuti, Arsyana Kurniasari, Gina Nadifah et autres

Hypercholesterolemia is recognized as a major risk factor for cardiovascular diseases and was commonly treated with long-term synthetic drugs, which were costly and associated with side effects. Medicinal plants, such as menteng (Baccaurea racemosa) leaves, have been explored as potential natural alternatives. …

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Lansioside E, an onoceranoid-type triterpenoid isolated from the fruit peel of Lansium domesticum Corr. cv. Kokossan and its cytotoxic activity against MCF-7 breast cancer cells

Tri Mayanti, Lutfiah Dwi Ramadhanti, Wahyu Safriansyah, Darwati Darwati et autres

Kokosan is a cultivar of Lansium domesticum (Meliaceae), and compounds in this variant remain limited. A new onoceranoid glycoside, lansioside E (1), along with two known onoceranoids, were isolated from the fruit peels of Kokosan. The structure of the new compound was …

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Diterpenoid compounds derived from meliaceae plants and biological activities

Noor Aishah Najihah, Wahyu Safriansyah, Siska Elisahbet Sinaga, Mohd Azlan Nafiah et autres

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