Camilo Berríos-Pastén

Genomic insights into the first blaKPC-2-carrying Klebsiella pneumoniae isolate reported in Chile: limited local dissemination of the globally distributed ST101 lineage

Maximiliano Matus-Köhler, Camilo Berríos-Pastén, Nicolás Guerra-Leal, Nahuel Pilquinao et autres

ABSTRACT Objective To genomically characterize Kpn-KPC-1, the first bla KPC-2 -carrying Klebsiella pneumoniae isolate reported in Chile, and contextualize it within the global ST101 lineage. Methods Kpn-KPC-1 was analyzed by whole-genome sequencing. Its resistome, virulome, plasmid content, and bla KPC-2 genetic context …

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GenBank Accession Numbers of Antarctic soil microbiomes encode structurally conserved and phylogenetically diverse beta-lactamases

José Coche-Miranda, Patricio Arros, Nicolás Canales, Camilo Berríos-Pastén et autres

This dataset contains the accession numberf for 10 soil metagenome sequences collected in the Antarctic Peninsula and the South Shetland Islands during the Chilean Scientific Expedition ECA55 (2018) and ECA57 (2019) published in the BioProject PRJNA1425240 . Locality, latitude, longitude collection date …

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GenBank Accession Numbers of Antarctic soil microbiomes encode structurally conserved and phylogenetically diverse beta-lactamases

José Coche-Miranda, Patricio Arros, Nicolás Canales, Camilo Berríos-Pastén et autres

This dataset contains the accession numberf for 10 soil metagenome sequences collected in the Antarctic Peninsula and the South Shetland Islands during the Chilean Scientific Expedition ECA55 (2018) and ECA57 (2019) published in the BioProject PRJNA1425240 . Locality, latitude, longitude collection date …

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Antarctic soil microbiomes encode structurally conserved and phylogenetically diverse beta‐lactamases

José Coche-Miranda, Patricio Arros, Nicolás Canales, Camilo Berríos-Pastén et autres

Abstract Antimicrobial resistance is a major global health threat shaped not only by clinical settings but also by environmental reservoirs, in line with the One Health framework. Antarctic and Subantarctic soils represent a largely unexplored component of the environmental resistome, particularly beta‐lactamases, …

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The GMI-K70 collection: precisely annotated genomic islands, integration sites, and a novel tRNA gene nomenclature across the Klebsiella genus

Camilo Berríos-Pastén, Rodolfo Acevedo, Carlos Serrano-Pinto, Patricio Arros et autres

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The GMI-K70 collection: precisely annotated genomic islands, integration sites, and a novel tRNA gene nomenclature across the Klebsiella genus

Camilo Berríos-Pastén, Andrés E. Marcoleta

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The GMI-K70 collection: precisely annotated genomic islands, integration sites, and a novel tRNA gene nomenclature across the Klebsiella genus

Camilo Berríos-Pastén, Andrés E. Marcoleta

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Intrinsic class C extended-spectrum β-lactamases mediate resistance to oxyimino-cephalosporins in Antarctic Pseudomonas fluorescens complex bacteria

José Coche-Miranda, Iyaray Cespedes-Navarro, Bruno Cardemil, Patricio Arros et autres

ABSTRACT From a One Health perspective, identifying environmental reservoirs of antibiotic resistance determinants with potential clinical relevance is increasingly important. Among resistance mechanisms, β-lactamases are of particular concern because they compromise the efficacy of β-lactam antibiotics, the most widely used class in …

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A structure-guided pipeline to uncover the underexplored beta-lactamases from Antarctic and Subantarctic soil microbiota

José Coche-Miranda, Patricio Arros, Camilo Berríos-Pastén, Rosalba Lagos et autres

ABSTRACT As the One Health approach points out, the environment can significantly affect human health, particularly having diverse and profound implications in the ongoing antimicrobial resistance crisis. One central aspect is the potential role of environmental microorganisms as a source of resistance …

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Large-scale analysis of polyhydroxyalkanoate synthases in Pseudomonas : highly diverse enzymes with potential for a novel class and dissemination by horizontal gene transfer

Amelia Cox-Fermandois, Camilo Berríos-Pastén, Carlos Serrano, Patricio Arros et autres

AIMS: To investigate the diversity, phylogenetic distribution, and structural features of polyhydroxyalkanoate (PHA) synthases (PhaCs), key enzymes for producing bioplastics, in different well-known and poorly-studied species of Pseudomonas. As Antarctic Pseudomonas spp. with unique PhaCs and PHA synthesis capabilities have been reported, …

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Pseudomonas species from Antarctica and other environments host diverse genes encoding structurally conserved polyhydroxyalkanoate synthases linked with different mobile genetic elements

Amelia Cox-Fermandois, Camilo Berríos-Pastén, Carlos Serrano, Patricio Arros et autres

ABSTRACT Polyhydroxyalkanoates (PHAs) are industrial microbial biopolymers offering a sustainable and biodegradable alternative to petroleum-based plastics. The PHA polymerization process is primarily mediated by PHA synthases (PhaCs), which determine the molecular and physical properties of the synthesized polymers. Previous reports have described …

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Microbial Printmaking for Teaching Antimicrobial Action and Resistance

André Barbet, Camilo Berríos-Pastén, Macarena A. Varas, Julieta Orlando et autres

Antimicrobial resistance is among the most pressing health threats globally, prompting the call for urgent actions, including education on this topic. In this direction, engaging teaching activities applicable to a broad audience are required. Here, we describe a visually attractive and didactic …