Lél Eöry

Transcriptomic characterisation of acute myeloid leukemia cell lines bearing the same t(9;11) driver mutation reveals different molecular signatures

Elise Georges, William Ho, Miren Urrutia Iturritza, Lél Eöry et autres

BACKGROUND: Acute myeloid leukemia (AML) is the most common type of acute leukemia, accounting for 20% of cases in children and adolescents. Genome-wide studies have identified genes that are commonly mutated in AML, including many epigenetic regulators involved in either DNA methylation …

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Supplementary Figures 1-2, Supplementary Tables 1-2 from Sunitinib Treatment Exacerbates Intratumoral Heterogeneity in Metastatic Renal Cancer

Grant D. Stewart, Fiach C. O’Mahony, Alexander Laird, Lél Eöry et autres

Supplementary Figures 1-2, Supplementary Tables 1-2. Fig. S1. Histogram showing lack of correlation between differential protein and RNA expression levels between sunitinib naive and treated patient samples; Figure S2: Dendrograms illustrating supervised Euclidean clustering of copy number variations (AC) and gene expression …

Data from Sunitinib Treatment Exacerbates Intratumoral Heterogeneity in Metastatic Renal Cancer

Grant D. Stewart, Fiach C. O’Mahony, Alexander Laird, Lél Eöry et autres

Abstract Purpose: The aim of this study was to investigate the effect of VEGF-targeted therapy (sunitinib) on molecular intratumoral heterogeneity (ITH) in metastatic clear cell renal cancer (mccRCC). Experimental Design: Multiple tumor samples (n = 187 samples) were taken from the primary …

Data from Sunitinib Treatment Exacerbates Intratumoral Heterogeneity in Metastatic Renal Cancer

Grant D. Stewart, Fiach C. O’Mahony, Alexander Laird, Lél Eöry et autres

Abstract Purpose: The aim of this study was to investigate the effect of VEGF-targeted therapy (sunitinib) on molecular intratumoral heterogeneity (ITH) in metastatic clear cell renal cancer (mccRCC). Experimental Design: Multiple tumor samples (n = 187 samples) were taken from the primary …

Supplementary Figures 1-2, Supplementary Tables 1-2 from Sunitinib Treatment Exacerbates Intratumoral Heterogeneity in Metastatic Renal Cancer

Grant D. Stewart, Fiach C. O’Mahony, Alexander Laird, Lél Eöry et autres

Supplementary Figures 1-2, Supplementary Tables 1-2. Fig. S1. Histogram showing lack of correlation between differential protein and RNA expression levels between sunitinib naive and treated patient samples; Figure S2: Dendrograms illustrating supervised Euclidean clustering of copy number variations (AC) and gene expression …

752. Applications of single-molecule real-time isoform sequencing (Iso-Seq) for unravelling complexity of dog transcriptomes

W. Zhang, Lél Eöry, Mazdak Salavati, Emily L. Clark et autres

Here we present a summary of the generation of dog Single-molecule Real-time Isoform Sequencing (Iso-Seq) data, and its application for transcriptome annotation. Iso-Seq libraries from six tissues were sequenced, and read clean-up was implemented with IsoSeq V3 tools. A high retention rate …

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Stem cell-derived porcine macrophages as a new platform for studying host-pathogen interactions

Stephen E. Meek, Tom Watson, Lél Eöry, Gus R. McFarlane et autres

BACKGROUND: Infectious diseases of farmed and wild animals pose a recurrent threat to food security and human health. The macrophage, a key component of the innate immune system, is the first line of defence against many infectious agents and plays a major …

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A high-quality genome and comparison of short- versus long-read transcriptome of the palaearctic duck Aythya fuligula (tufted duck)

Ralf C. Mueller, Patrik Ellström, Kerstin Howe, Marcela Uliano‐Silva et autres

BACKGROUND: The tufted duck is a non-model organism that experiences high mortality in highly pathogenic avian influenza outbreaks. It belongs to the same bird family (Anatidae) as the mallard, one of the best-studied natural hosts of low-pathogenic avian influenza viruses. Studies in …

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Correction to: Avian Immunome DB: an example of a user‑friendly interface for extracting genetic information

Ralf C. Mueller, Nicolai Mallig, Jacqueline Smith, Lél Eöry et autres

Following publication of the original article [1], the authors identifed an error in the author name of Lél Eöry. Te incorrect author name is: Lél Eöery. Te correct author name is: Lél Eöry. Te author group has been updated above and the …

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Stem cell-derived macrophages as a new platform for studying host-pathogen interactions in livestock

Stephen E. Meek, Tom Watson, Lél Eöry, Gus R. McFarlane et autres

Abstract Infectious diseases of farmed and wild animals pose a recurrent threat to food security and human health. The macrophage, a key component of the innate immune system, is the first line of defence against many infectious agents and plays a major …

gb, de, us, cn, hk (code pays fourni par la source)

A chromosome-level genome assembly for the Pacific oyster Crassostrea gigas

Carolina Peñaloza, Alejandro P. Gutiérrez, Lél Eöry, Shan Wang et autres

BACKGROUND: The Pacific oyster (Crassostrea gigas) is a bivalve mollusc with vital roles in coastal ecosystems and aquaculture globally. While extensive genomic tools are available for C. gigas, highly contiguous reference genomes are required to support both fundamental and applied research. Herein …

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A high-quality Genome and Comparison of Short versus Long Read Transcriptome of the Palaearctic duck Aythya fuligula (Tufted Duck)

Ralf C. Mueller, Patrik Ellström, Kerstin Howe, Marcela Uliano‐Silva et autres

Background The tufted duck is a non-model organism that suffers high mortality in highly pathogenic avian influenza out-breaks. It belongs to the same bird family (Anatidae) as the mallard, one of the best-studied natural hosts of low-pathogenic avian influenza viruses. Studies in …

de, se, gb, us (code pays fourni par la source)