Katrine Kjær Iversen

Recovery of lung function during the first year after COVID-19: a systematic review and meta-analysis

Katrine Kjær Iversen, Marcus Sebastian Roldgaard, Ioannis Konstantinidis, Magnus Søltoft Lindhardt et autres

Background Several studies have reported lung function impairment following COVID-19. Less is known about the subsequent recovery. Research question What is the recovery in lung function after COVID-19 during the first year after infection? Methods We conducted a systematic review and meta-analysis …

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The Predictive Role of C-Reactive Protein, Leukocyte Cell Count, and Soluble Urokinase Plasminogen Activator Receptor for Pulmonary Sequelae in Hospitalized COVID-19 Survivors: A Prospective Single-Center Cohort Study

Izzet Altintas, Thomas Kallemose, Mette Bendtz Lindstroem, Imran Parvaiz et autres

Background: Pulmonary function impairment significantly affects quality of life, work ability, and healthcare utilization. Among patients with COVID-19, respiratory symptoms vary in severity. This study aimed to assess whether biomarkers related to respiratory function and inflammation at emergency department (ED) admittance can …

dk (code pays fourni par la source)

The Predictive Role of C-Reactive Protein, Leukocyte Cell Count, and Soluble Urokinase Plasminogen Activator Receptor for Pulmonary Sequelae in Hospitalized COVID-19 Survivors: A Prospective Single-Center Cohort Study

Izzet Altintas, Thomas Kallemose, Mette Bendtz Lindstrøm, Imran Parvaiz et autres

dk (code pays fourni par la source)

P47 Organ calcifications in patients with systemic lupus erythematosus

Tobias T. Schmidt, Amanda Hempel Zinglersen, Katrine Kjær Iversen, Louise Pyndt Diederichsen et autres

Objective Tissue calcifications or calcinosis have been described to occur in a variety of systemic autoimmune diseases, even being a significant part of the clinical picture for example in systemic sclerosis or dermatomyositis. In Systemic Lupus Erythematosus (SLE), various types of calcinoses …

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P48 Differentiated anatomical distribution of cardiovascular calcifications in patients with systemic lupus erythematosus (SLE) compared to healthy population controls (HC)

Tobias Phillip Schmidt, Amanda Hempel Zinglersen, Katrine Kjær Iversen, Andreas Fuchs et autres

Objective Systemic Lupus Erythematosus (SLE) patients without prior cardiovascular events present an increased prevalence of atherosclerotic carotid plaques, coronary artery calcifications (CAC), and signs of peripheral artery disease compared to matched healthy population controls (HC). Thus, we investigated whether vascular calcifications in …

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Viral and Host Factors Are Associated With Mortality in Hospitalized Patients With COVID-19

Neil R. Aggarwal, Jacquie Nordwall, Dominique L. Braun, Lucy K. Chung et autres

BACKGROUND: Persistent mortality in adults hospitalized due to acute COVID-19 justifies pursuit of disease mechanisms and potential therapies. The aim was to evaluate which virus and host response factors were associated with mortality risk among participants in Therapeutics for Inpatients with COVID-19 …

us, ch, Nigéria, es, dk, gb, gr (code pays fourni par la source)

Lung Function Trajectories in Mild COVID-19 With 2-year Follow-up

Katrine Kjær Iversen, Andreas Ronit, Magnus Glindvad Ahlström, Børge Grønne Nordestgaard et autres

BACKGROUND: The long-term pulmonary sequelae of mild coronavirus disease 2019 (COVID-19) remains unknown. In this study, we aimed to characterize lung function trajectories in individuals with mild COVID-19 from preinfection to 2 years postinfection. METHODS: We reinvited participants 2 years after infection …

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Effect of Neutralizing Monoclonal Antibody Treatment on Early Trajectories of Virologic and Immunologic Biomarkers in Patients Hospitalized With COVID-19

Tomas Østergaard Jensen, Greg Grandits, Mamta K. Jain, Thomas A. Murray et autres

BACKGROUND: Neutralizing monoclonal antibodies (nmAbs) failed to show clear benefit for hospitalized patients with coronavirus disease 2019 (COVID-19). Dynamics of virologic and immunologic biomarkers remain poorly understood. METHODS: Participants enrolled in the Therapeutics for Inpatients with COVID-19 trials were randomized to nmAb …

dk, us, gb, gr, Ouganda, au (code pays fourni par la source)

Lung Abnormalities in Severe Acute Respiratory Syndrome Coronavirus 2 Infection: An Analysis of Paired Computed Tomography Scans Before and After Infection

Katrine Kjær Iversen, Andreas Ronit, Thomas Skårup Kristensen, Shoaib Afzal et autres

Abstract Background Studies on the pulmonary consequences of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are impeded by limited access to pre–SARS-CoV-2 examinations. Methods We invited Copenhagen General Population Study participants with a confirmed SARS-CoV-2 polymerase chain reaction (PCR) test during …

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A randomized placebo-controlled trial of convalescent plasma for adults hospitalized with COVID-19 pneumonia

Louise Thorlacius-Ussing, Patrick Terrence Brooks, Henrik Ib Nielsen, Bitten Aagaard Jensen et autres

Passive immunotherapy with convalescent plasma may be the only available agent during the early phases of a pandemic. Here, we report safety and efficacy of high-titer convalescent plasma for COVID-19 pneumonia. Double-blinded randomized multicenter placebo-controlled trial of adult patients hospitalized with COVID-19 …

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Left ventricular size and function in patients with systemic lupus erythematosus associate with lupus anticoagulant: An echocardiographic follow-up study

Katrine Aagaard Myhr, Amanda Hempel Zinglersen, Marie‐Louise From Hermansen, Mathies M. Jepsen et autres

BACKGROUND: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with increased risk of cardiac dysfunction. The pathophysiological mechanisms are poorly understood, and prognostic markers are warranted. PURPOSE: We aimed to identify SLE-characteristics associated with measures of cardiac size and function during …

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Efficacy and Safety of Ensovibep for Adults Hospitalized With COVID-19

Eleftherios E Mylonakis, Barnaby Edward Young, David M. Vock, Lianne K. Siegel et autres

BACKGROUND: Ensovibep (MP0420) is a designed ankyrin repeat protein, a novel class of engineered proteins, under investigation as a treatment of SARS-CoV-2 infection. OBJECTIVE: To investigate if ensovibep, in addition to remdesivir and other standard care, improves clinical outcomes among patients hospitalized …

us, gr, sg, Ouganda, gb, Nigéria, ch, dk, au, es, pl (code pays fourni par la source)