Louiza Chan

Independent Mobility Achieved through a Wireless Brain-Machine Interface

Camilo Libedinsky, Rosa Q. So, Zhiming Xu, Toe K. Kyar et autres

Individuals with tetraplegia lack independent mobility, making them highly dependent on others to move from one place to another. Here, we describe how two macaques were able to use a wireless integrated system to control a robotic platform, over which they were …

sg (code pays fourni par la source)

Germline and somatic imprinting in the nonhuman primate highlights species differences in oocyte methylation

Clara Yujing Cheong, Keefe Chng, Shilen Ng, Siew Boom Chew et autres

Genomic imprinting is an epigenetic mechanism resulting in parental allele-specific gene expression. Defects in normal imprinting are found in cancer, assisted reproductive technologies, and several human syndromes. In mouse models, germline-derived DNA methylation is shown to regulate imprinting. Though imprinting is largely …

sg, gb (code pays fourni par la source)

Classification of phases of hand grasp task by the extraction of miniature compound nerve action potentials (mCNAPs)

Swathi Sheshadri, Jukka Kortelainen, Jacopo Rigosa, Annarita Cutrone et autres

Interfacing with the nervous system to restore functional motor activity is a promising therapy to augment the classical surgical approaches to treating peripheral nerve injuries. Despite the advances in electrode microelectronics engineering, the challenge of extracting information from injured nerves to help …

sg, fi, it (code pays fourni par la source)

Alterations to DNA methylation and expression of CXCL14 are associated with suboptimal birth outcomes

Clara Yujing Cheong, Keefe Chng, Mei Kee Lim, Ajith Isaac Amrithraj et autres

sg (code pays fourni par la source)

Correlation between muscular and nerve signals responsible for hand grasping in non-human primates

Swathi Sheshadri, Jukka Kortelainen, Sudip Nag, Kian Ann Ng et autres

Neuroprosthetic devices that interface with the nervous system to restore functional motor activity offer a viable alternative to nerve regeneration, especially in proximal nerve injuries like brachial plexus injuries where muscle atrophy may set in before nerve re-innervation occurs. Prior studies have …

sg, fi, ch (code pays fourni par la source)

Infinium Monkeys: Infinium 450K Array for the Cynomolgus macaque (Macaca fascicularis)

Mei‐Lyn Ong, Peck Yean Tan, Julia L. MacIsaac, Sarah M Mah et autres

The Infinium Human Methylation450 BeadChip Array (Infinium 450K) is a robust and cost-efficient survey of genome-wide DNA methylation patterns. Macaca fascicularis (Cynomolgus macaque) is an important disease model; however, its genome sequence is only recently published, and few tools exist to interrogate …

sg, ca (code pays fourni par la source)

Gonadotropin-Inhibitory Hormone Is a Hypothalamic Peptide That Provides a Molecular Switch between Reproduction and Feeding

Iain James Clarke, Jeremy T. Smith, Belinda A. Henry, Brian J. Oldfield et autres

OBJECTIVE: Gonadotropin-inhibitory hormone (GnIH)-3 is a neuropeptide that plays a major role in the regulation of reproduction and feeding in mammals. MATERIALS AND METHODS: We measured endocrine and behavioural parameters of reproduction in sheep, and sexual behaviour in sheep, mice and cynomolgus …

au, sg, fr, us (code pays fourni par la source)

Contents Vol. 95, 2012

Byoung‐Seob Ko, Iain James Clarke, Jeremy T. Smith, Belinda A. Henry et autres