Elisabeth Straka

POS1109 USE OF LUNG ULTRASOUND FOR SCREENING FOR SYSTEMIC AUTOIMMUNE RHEUMATIC DISEASE-ASSOCIATED INTERSTITIAL LUNG DISEASES IN CENTRAL AND EASTERN EUROPE

Maria Sanzharovskaya, Yochai Adir, Alan Altraja, R. Bekenova et autres

Background: Lung ultrasound (LUS) is a promising tool for screening for interstitial lung disease (ILD) in patients with systemic autoimmune rheumatic diseases (SARDs). However, data on the frequency of its use as a screening tool in clinical practice are limited. Objectives: To …

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Screening for Systemic Autoimmune Rheumatic Disease-Associated Interstitial Lung Disease in Central and Eastern Europe

Maria Sanzharovskaya, Р. А. Бакенова, Pascal Baltzer, Cătălin Codreanu et autres

Abstract Rationale: Guidelines for screening for interstitial lung disease (ILD) in patients with systemic autoimmune rheumatic diseases (SARDs) have recently been published by the American College of Rheumatology and American College of Chest Physicians. We assessed practices for screening for SARD-ILD among …

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Supplementary Methods, Figure Legends from STAT5 Is a Key Regulator in NK Cells and Acts as a Molecular Switch from Tumor Surveillance to Tumor Promotion

Dagmar Gotthardt, Eva Maria Putz, Eva Grundschober, Michaela Prchal-Murphy et autres

Supplementary Methods, Figure Legends

Supplementary Figures S1 - S8 from STAT5 Is a Key Regulator in NK Cells and Acts as a Molecular Switch from Tumor Surveillance to Tumor Promotion

Dagmar Gotthardt, Eva Maria Putz, Eva Grundschober, Michaela Prchal-Murphy et autres

Supplementary Figure S1. Stat5 expression correlates with the expression of anti-apoptotic genes. Supplementary Figure S2. STAT5-deficient NK cells possess aberrant transcription factors expression. Supplementary Figure S3. Loss of STAT5 alters granzyme, perforin and IFN-gamma production. Supplementary Figure S4. STAT5-deficient NK cells induce …

Supplementary Methods, Figure Legends from STAT5 Is a Key Regulator in NK Cells and Acts as a Molecular Switch from Tumor Surveillance to Tumor Promotion

Dagmar Gotthardt, Eva Maria Putz, Eva Grundschober, Michaela Prchal-Murphy et autres

Supplementary Methods, Figure Legends

Supplementary Figures S1 - S8 from STAT5 Is a Key Regulator in NK Cells and Acts as a Molecular Switch from Tumor Surveillance to Tumor Promotion

Dagmar Gotthardt, Eva Maria Putz, Eva Grundschober, Michaela Prchal-Murphy et autres

Supplementary Figure S1. Stat5 expression correlates with the expression of anti-apoptotic genes. Supplementary Figure S2. STAT5-deficient NK cells possess aberrant transcription factors expression. Supplementary Figure S3. Loss of STAT5 alters granzyme, perforin and IFN-gamma production. Supplementary Figure S4. STAT5-deficient NK cells induce …

Data from STAT5 Is a Key Regulator in NK Cells and Acts as a Molecular Switch from Tumor Surveillance to Tumor Promotion

Dagmar Gotthardt, Eva Maria Putz, Eva Grundschober, Michaela Prchal-Murphy et autres

Abstract Natural killer (NK) cells are tightly regulated by the JAK–STAT signaling pathway and cannot survive in the absence of STAT5. We now report that STAT5-deficient NK cells can be rescued by overexpression of BCL2. Our experiments define STAT5 as a master …

Data from STAT5 Is a Key Regulator in NK Cells and Acts as a Molecular Switch from Tumor Surveillance to Tumor Promotion

Dagmar Gotthardt, Eva Maria Putz, Eva Grundschober, Michaela Prchal-Murphy et autres

Abstract Natural killer (NK) cells are tightly regulated by the JAK–STAT signaling pathway and cannot survive in the absence of STAT5. We now report that STAT5-deficient NK cells can be rescued by overexpression of BCL2. Our experiments define STAT5 as a master …

Elevated metallothionein expression in long-lived species mediates the influence of cadmium accumulation on aging

Kamil Pabis, Ylenia Chiari, Claudia Sala, Elisabeth Straka et autres

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Genetics of the human placenta: implications for toxicokinetics

Claudia Gundacker, Jürgen Neesen, Elisabeth Straka, Isabella Ellinger et autres

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Don't trust an(t)ybody - Pitfalls during investigation of candidate proteins for methylmercury transport at the placental interface

Isabella Ellinger, Waranya Chatuphonprasert, Martin Reiter, Agnes Voss et autres

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STAT5 Is a Key Regulator in NK Cells and Acts as a Molecular Switch from Tumor Surveillance to Tumor Promotion

Dagmar Gotthardt, Eva Maria Putz, Eva Grundschober, Michaela Prchal‐Murphy et autres

UNLABELLED: Natural killer (NK) cells are tightly regulated by the JAK-STAT signaling pathway and cannot survive in the absence of STAT5. We now report that STAT5-deficient NK cells can be rescued by overexpression of BCL2. Our experiments define STAT5 as a master …

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