Konain Fatima Bhatti

Contribution of dominant and recessive model effects to the genetic architecture of Idiopathic Pulmonary Fibrosis

Tamara Hernandez Beeftink, Lauren J. Donoghue, Abril G. Izquierdo, Samuel T Moss et autres

Rationale: Idiopathic pulmonary fibrosis (IPF) is a rare, chronic, progressive lung disease with high mortality and few treatment options. Using an additive genetic model, genome-wide association studies (GWAS) have identified multiple risk loci highlighting new genes and pathways of interest. Since IPF …

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A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids

Véronique Vitart, Stefan Weiß, Jeanette Erdmann, Kristian Hveem et autres

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Author Correction: The power of genetic diversity in genome-wide association studies of lipids

Jirong Long, Ketian Yu, Alaitz Poveda, Shweta Ramdas et autres

us (code pays fourni par la source)

The power of genetic diversity in genome-wide association studies of lipids

Jette Bork‐Jensen, Joel N. Hirschhorn, Zoltán Kutalik, Sanni Ruotsalainen et autres

us (code pays fourni par la source)

Correction to: The power of genetic diversity in genome-wide association studies of lipids (Nature, (2021), 600, 7890, (675-679), 10.1038/s41586-021-04064-3)

Sarah E. Graham, Shoa L. Clarke, Kuan Han H. Wu, Stavroula Kanoni et autres

Correction to: Naturehttps://doi.org/10.1038/s41586-021-04064-3 Published online 9 December 2021 In the version of this article initially published, Noha A. Yousri (Department of Genetic Medicine, Weill Cornell Medicine-Qatar, Doha, Qatar and Department of Computer and Systems Engineering, Alexandria University, Egypt) and Steven C. Hunt …

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Author Correction: The power of genetic diversity in genome-wide association studies of lipids

Sarah E. Graham, Shoa L. Clarke, Kuan-Han H. Wu, Stavroula Kanoni et autres

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Additional file 28 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis

Stavroula Kanoni, Sarah E. Graham, Yuxuan Wang, Ida Surakka et autres

Additional file 28: Table S18. Sex-participation association of the variants with significant sex-specific lipid results.

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Additional file 21 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis

Stavroula Kanoni, Sarah E. Graham, Yuxuan Wang, Ida Surakka et autres

Additional file 21: Table S13. Characteristics of replication cohorts (as provided by each participating cohort).

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Additional file 25 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis

Stavroula Kanoni, Sarah E. Graham, Yuxuan Wang, Ida Surakka et autres

Additional file 25: Table S16. Comparison of effect size estimates for sex-stratified analysis in the replication cohorts.

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Additional file 18 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis

Stavroula Kanoni, Sarah E. Graham, Yuxuan Wang, Ida Surakka et autres

Additional file 18: Table S10. Lambda GC values across minor allele frequency bins for sex-specific meta-analyses.

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Additional file 27 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis

Stavroula Kanoni, Sarah E. Graham, Yuxuan Wang, Ida Surakka et autres

Additional file 27: Table S17. Sex-stratified effect sizes in UK Biobank considering all individuals or only those not on cholesterol lowering medications.

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Additional file 10 of Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis

Stavroula Kanoni, Sarah E. Graham, Yuxuan Wang, Ida Surakka et autres

Additional file 10: Table S7. DESE phenotype-tissue association results using both GTEx gene-level and transcript-level selective expression.

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