Amy Mizen

Linking Place-Based Exposures and Genomics to understand Human Phenotypes

Amy Foreman, Abigail Harrison, Amy Mizen, Andy Boyd et autres

Evidence that the environment has a greater impact on health than genomics alone is driving a need to understand exposure impacts and their interactions at scale. Geospatially tagged exposure data, such as for weather, climate and pollution, along with social factors associated …

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Linking Place-Based Exposures and Genomics to understand Human Phenotypes

Amy Foreman, Abigail Harrison, Amy Mizen, Andy Boyd et autres

Evidence that the environment has a greater impact on health than genomics alone is driving a need to understand exposure impacts and their interactions at scale. Geospatially tagged exposure data, such as for weather, climate and pollution, along with social factors associated …

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impact of early life exposure to green space on mental health-related service use for mood or anxiety disorders in adolescence and early adulthood: A population-based birth cohort study in Ontario, Canada

Amy Mizen, Martin Rotenburg, Stephanie Dixon, Britney Le et autres

Rates of anxiety and depression among adolescents are rising globally. Exposure to greenness is recognised as a determinant of mental health but little is known about its impacts on adolescent mental health on a population scale. We examined the prospective association between …

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Comparing temperature exposure with time to birth using Bayesian joint models at population-scale; computationally tractable methods for exploring temporal associations incorporating full-parameter uncertainty

James Rafferty, Amir Baniasadi, Wally Abdeldayem, SL Turner et autres

Climate change is affecting our world, and the impact of rising temperatures on health is not well understood. Prior work found exposure to heat was associated with reduced gestational age, increased prematurity and smaller birth weights. The goal of the Maternal and …

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Characterising Residential Environments for Children: A Nationwide Linked Data Approach to Mapping Built and Natural Features

Jo Davies, Rowena Bailey, Amy Mizen, Dora Pouliou et autres

Background: The environments where children live play a critical role in shaping health trajectories, yet comprehensive population-level descriptions of these environments remain limited. Understanding residential environmental characteristics is essential for informing urban planning and public health strategies aimed at creating child-friendly neighbourhoods. …

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Ascertaining Household-Level Exposure to Air Pollution: Socio-Demographic Patterning and Urban-Rural Differences in People with Schizophrenia and Other Psychotic Disorders and the General Population

Ella Christoforou, Jane Lyons, Ann John, Rich Fry et autres

BackgroundPeople with severe mental disorders, including schizophrenia, experience worse physical health and shorter life expectancy. While socio-demographic factors are well established contributors to these disparities, less is known about how environmental exposures differ between individuals with severe mental disorders and the general …

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Maternal And preGnancy hEalth aNd elevaTed heAt (MAGENTA): protocol for a novel data linkage study exploring the association between temperature and pregnancy outcomes in Wales and London, UK

Samantha Turner, Amy Mizen, Catherine A. Thornton, Rhiannon Kate Owen et autres

There is growing evidence on the adverse health impacts of global warming, particularly amongst more vulnerable populations such as pregnant women and their newborns. However, evidence on the impacts of heat on maternal and neonatal health in the UK remains limited. The …

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Child Outcomes for Mothers Facing Trial (COMFT) : Protocol for a multinational data linkage study to understand caregiver arrangements for children of mothers involved in the criminal and family justice systems

Karen Broadhurst, Bachar Alrouh, Leslie Humphreys, Laura E. Cowley et autres

Background An unknown proportion of mothers are involved in both the Criminal Justice and Family Justice Systems. Mothers with cross-justice involvement are at risk of losing their children from their care on a temporary or permanent basis. Objectives Speaking directly to the …

Child Outcomes for Mothers Facing Trial (COMFT): Protocol for a multi-national data linkage study to understand caregiver arrangements for children of mothers involved in the criminal and family justice systems

Karen Broadhurst, Bachar Alrouh, Leslie Humphreys, Laura Cowley et autres

BackgroundAn unknown proportion of mothers are involved in both the Criminal Justice and Family Justice Systems. Mothers with cross-justice involvement are at risk of losing their children from their care on a temporary or permanent basis. ObjectivesSpeaking directly to the Female Offender …

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Environmental phenotypes for healthy weight in children using population-based linked environment and health data: a cross-sectional observational study

Jo Davies, Rowena Bailey, Rebecca Pedrick-Case, Gareth Stratton et autres

BACKGROUND: Childhood obesity is a major global health challenge, projected to affect one in three children worldwide by 2050. While individual and social factors contribute, increasing evidence highlights the built environment as a key determinant in shaping children's behaviours and weight outcomes. …

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Unequal Heat Exposure across Wales: A Spatio-Temporal Analysis of Socioeconomic Deprivation

Amir Arsalan Baniasadi, Wally Abdeldayem, Lucy Griffith, Rhiannon Owen et autres

This study examines spatial and temporal inequalities in outdoor heat exposure across Wales and their association with socioeconomic deprivation. Using MODIS-derived land surface temperature (2010– 2023), the Welsh Index of Multiple Deprivation and spatio-temporal weighted regression, the analysis explicitly identifies where and …

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Unequal Heat Exposure across Wales: A Spatio-Temporal Analysis of Socioeconomic Deprivation

Amir Arsalan Baniasadi, Wally Abdeldayem, Lucy Griffith, Rhiannon Owen et autres

This study examines spatial and temporal inequalities in outdoor heat exposure across Wales and their association with socioeconomic deprivation. Using MODIS-derived land surface temperature (2010– 2023), the Welsh Index of Multiple Deprivation and spatio-temporal weighted regression, the analysis explicitly identifies where and …

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