Takamasa Kido

Intracellular localization of Al₂O₃ and CeO₂ nanoparticles is associated with the absence of detectable genotoxicity in CHL/IU cells

Hiroyuki Yanagisawa, Takamasa Kido, Machi Suka

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亜鉛欠乏が耐糖能障害の発症に及ぼす影響の解析 (第142回成医会総会一般演題)

Natsumi Desaka, Takamasa Kido, Hiroyuki Yanagisawa, Machi Suka

Systematic review of the effect of educational disparities on health disparities in childhood and thereafter.

Effects of poly(acrylic acid)’s crosslinker content on pulmonary toxicity in rats

Masayuki Yokoyama, Takamasa Kido, Koichi Shiraishi, Machi Suka et autres

For many years, poly(acrylic acid) (PAA) was considered an almost perfectly safe material, but in 2017, reports surfaced of pulmonary toxicity in workers who had handled crosslinked PAA particles at a Japanese factory. To elucidate the chemical compositions and physical properties that …

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Zinc Deficiency Reduces Intestinal Secretory Immunoglobulin A and Induces Inflammatory Responses via the Gut‐Liver Axis

Takamasa Kido, Hiroyuki Yanagisawa, Machi Suka

Nutritional zinc (Zn) deficiency could impair immune function and affect bowel conditions. However, the mechanism by which Zn deficiency affects the immune function of gut-associated lymphoid tissue (GALT) remains unclear. We investigated how Zn deficiency affects the function of GALT and level …

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Rate of hydrolysis of the phosphate esters of B vitamins is reduced by zinc deficiency: Invitro and invivo

Hana Yuasa, Kiyoshi Miyazaki, Takamasa Kido, Katsutoshi Nishino et autres

Extracellular hydrolysis of the phosphate esters of B vitamins (B1, B2, and B6) is crucial for their cellular uptake and metabolism. Although a few zinc-dependent enzymes have been implicated in these processes, their exact mechanisms of action remain largely unknown. This study …

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Rate of hydrolysis of the phosphate esters of B vitamins is reduced by zinc deficiency: In vitro and in vivo

Hana Yuasa, Kiyoshi Miyazaki, Takamasa Kido, Katsutoshi Nishino et autres

Extracellular hydrolysis of the phosphate esters of B vitamins (B1, B2, and B6) is crucial for their cellular uptake and metabolism. Although a few zinc-dependent enzymes have been implicated in these processes, their exact mechanisms of action remain largely unknown. This study …

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Zinc deficiency affects insulin secretion and alters insulin-regulated metabolic signaling in rats

Anna Nakamura, Takamasa Kido, Yoshiko Seki, Machi Suka

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Intratracheal administration of cross‐linked water‐soluble acrylic acid polymer is associated with inducible bronchi‐related lymphoid tissue formation and allergic inflammation

Takamasa Kido, Chiemi Sugaya, Hiroshi Hano, Hiroyuki Yanagisawa et autres

In a Japanese chemical factory, lung diseases such as pneumoconiosis have been reported among workers handling cross-linked water-soluble acrylic acid polymers (CWAAP). Our previous study reported that a single intratracheal administration of CWAAP induces acute inflammation and fibrosis. In this study, we …

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Zinc deficiency alters metabolism-related organ crosstalk via changing insulin levels

Anna Nakamura, Takamasa Kido, Yoshiko Seki, Machi Suka

Abstract Zinc is one of the essential trace elements that plays an important role in the biological processes in human beings. Zinc deficiency, therefore, is known to cause several biofunctional disorders. Zinc plays an important role in stabilizing the pancreatic insulin secretion. …

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Effectiveness of interleukin‐4 administration or zinc supplementation in improving zinc deficiency–associated thymic atrophy and fatty degeneration and in normalizing T cell maturation process

Takamasa Kido, Machi Suka, Hiroyuki Yanagisawa

Abstract Nutritional zinc deficiency induces thymic atrophy, but the underlying mechanisms remain unknown. In this study, we investigated the mechanism of thymic atrophy and fatty degeneration associated with zinc deficiency and its effect on T cell maturation. Building on previous research demonstrating …

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Ingestion of Excess Zinc Augments the Osmotic Fragility of Red Blood Cells via An Increase in Oxidative Stress

Eri Hachisuka, Takamasa Kido, Machi Suka, Hiroyuki Yanagisawa

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Single intratracheal administration of cross-linked water-soluble acrylic acid polymer causes acute alveolo-interstitial inflammation and the subsequent fibrotic formation possibly via the TGF-β1 pathway in the lung of rats

Machi Suka, Takamasa Kido, Wataru Yoshioka, Eri Hachisuka et autres

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