Emily A. H. Warren

How Clinicians Manage Sleep During Inpatient Hospitalization Following Pediatric Hematopoietic Stem Cell Transplantation

Lydia Chevalier, Eva Robinson, Edie Weller, Maike K. Klett et autres

Although pediatric hematopoietic stem cell transplantation (HSCT) patients often experience sleep disruptions during hospitalization, no clinical guidelines exist for how to manage their sleep. We sought to learn how clinicians approach inpatient sleep disruptions by surveying 111 pediatric HSCT medical prescribers, nurses, …

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Quality of life and mental health in pediatric patients with low-grade CNS tumors treated with surgery alone

Alexandra S. Roak, Sage P. Rahm, Sasha G. Howell, Anil K. Mahavadi et autres

OBJECTIVE: Pediatric patients with low-grade CNS tumors can experience an array of physical, cognitive, and psychosocial late effects, even in the absence of adjuvant therapy. It is unclear to what extent these late effects impact long-term quality of life (QOL). The aim …

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Mapping metabolic dependences and capacities using ATP as a biomarker

Peter J. McGuire, José J.G. Marı́n, Amanda L. Fuchs, Tatiana N. Tarasenko et autres

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Neuropsychological Late Effects and Quality-of-Life Outcomes in Pediatric Brain Tumor Survivors: Role of Pediatric Neurologists in Monitoring and Management

Iris Paltin, Megan Sy, Shannon M. Lundy, Lauren Ayr-Volta et autres

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Single-cell mapping of metabolic dependences using ATP as a biomarker

Peter J. McGuire, José J.G. Marı́n, Amanda L. Fuchs, Tatiana N. Tarasenko et autres

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Adaptive, behavioral, and emotional outcomes following postoperative pediatric cerebellar mutism syndrome in survivors treated for medulloblastoma

Kimberly P. Raghubar, Andrew M. Heitzer, Fatema Malbari, Jason S. Gill et autres

OBJECTIVE: Patients who experience postoperative pediatric cerebellar mutism syndrome (CMS) during treatment for medulloblastoma have long-term deficits in neurocognitive functioning; however, the consequences on functional or adaptive outcomes are unknown. The purpose of the present study was to compare adaptive, behavioral, and …

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Predicting neurocognitive function in pediatric brain tumor early survivorship: The neurological predictor scale and the incremental validity of tumor size

Mark D. McCurdy, Kimberly P. Raghubar, Krystal Christopher, Mehmet Fatih Okcu et autres

Abstract Background The Neurological Predictor Scale (NPS) quantifies cumulative exposure to conventional treatment‐related neurological risks but does not capture potential risks posed by tumors themselves. This study evaluated the predictive validity of the NPS, and the incremental value of tumor location and …

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Cognitive predictors of social adjustment in pediatric brain tumor survivors treated with photon versus proton radiation therapy

Emily A. H. Warren, Kimberly P. Raghubar, Paul T. Cirino, Amanda E. Child et autres

Abstract Background Pediatric brain tumor survivors are at risk for poor social outcomes. It remains unknown whether cognitive sparing with proton radiotherapy (PRT) supports better social outcomes relative to photon radiotherapy (XRT). We hypothesized that survivors treated with PRT would outperform those …

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Cognitive Predictors of Social Adjustment in Pediatric Brain Tumor Survivors Treated with Photon versus Proton Radiation Therapy

Emily A. H. Warren, Kimberly P. Raghubar, Paul T. Cirino, Amanda E. Child et autres

Background: Pediatric brain tumor survivors are at risk for poor social outcomes. It remains unknown whether cognitive sparing with proton radiotherapy (PRT) supports better social outcomes relative to photon radiotherapy (XRT). We hypothesized that survivors treated with PRT would outperform those treated …

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Long‐term cognitive and academic outcomes among pediatric brain tumor survivors treated with proton versus photon radiotherapy

Amanda E. Child, Emily A. H. Warren, David R. Grosshans, Arnold C. Paulino et autres

BACKGROUND: Proton radiotherapy (PRT) may be associated with less neurocognitive risk than photon RT (XRT) for pediatric brain tumor survivors. We compared neurocognitive and academic outcomes in long-term survivors treated with XRT versus PRT. METHODS: Survivors underwent neurocognitive evaluation >1 year after …

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Treatment age and neurocognitive outcomes following proton beam radiotherapy for pediatric low‐ and intermediate‐grade gliomas

Andrew M. Heitzer, Lisa S. Kahalley, Charles Gene Minard, Claire Stafford et autres

The relationship between age and neurocognitive functioning following proton beam radiotherapy (PRT) in low- and intermediate-grade gliomas (LIGG) has yet to be examined. Eighteen LIGG patients treated with PRT were prospectively enrolled and received annual neurocognitive evaluations of perceptual/verbal reasoning, working memory, …

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RONC-12. TREATMENT AGE AND NEUROCOGNITIVE OUTCOMES FOLLOWING PROTON BEAM RADIOTHERAPY FOR PEDIATRIC LOW GRADE GLIOMA

Andrew M. Heitzer, Lisa S. Kahalley, David R. Grosshans, Mehmet Fatih Okcu et autres

Abstract INTRODUCTION Younger age at radiotherapy increases cognitive risk for patients with pediatric low grade glioma (LGG). We examined the impact of age at treatment on cognitive trajectories in LGG patients treated with proton radiotherapy (PRT) compared to patients treated without radiotherapy …

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