Connor Jarrett Kinslow

Prognostic and Predictive Effect of Age in Molecularly Defined Lower-Grade Gliomas

Connor Jarrett Kinslow, Giuseppe Minniti, Paul David Brown, Michael A. Vogelbaum et autres

PURPOSE Age ≥40 years is regarded as a high-risk feature and an indication for adjuvant chemoradiotherapy for patients with lower-grade glioma in clinical practice guidelines. It is unclear whether age remains a relevant prognostic factor for contemporary definitions of lower-grade gliomas in …

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Abstract 2116: Genomic landscape of 1007 pan-cancer brain metastases.

Ramzi Homsi, Henry S. Walch, Roshal Patel, Anna Skakodub et autres

Abstract Background: The pan-cancer genomic landscape of brain metastases (BM) has not been well-characterized. Herein, we evaluate genomically profiled BM tumor samples and additional sequenced tumor samples from other sites to further understand disease evolution. Methods: We analyzed BM specimens from 1007 …

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Temporal dynamics of radiotherapy and chemotherapy response in lower-grade gliomas using causal machine learning

Everest Yang, Sparsh Agrawal, Connor Jarrett Kinslow, C. K. et autres

Lower-grade gliomas (World Health Organization [WHO] grades 2-3) exhibit variable treatment responses, yet clinical decisions remain guided by population-level trial results. Standard causal survival forests estimate treatment effects at individual time horizons but lack methodology to synthesize these into interpretable temporal trajectories. …

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Incidence of breast implant–associated anaplastic large cell lymphoma

Lauren S Lowe, Dylan K Kim, Christine Hsu Rohde, James B. Yu et autres

Abstract In 2020, the Food and Drug Administration mandated a black box warning on all breast implants, warning of an association with anaplastic large cell lymphoma (ALCL). The World Health Organization recently introduced breast implant–associated anaplastic large cell lymphoma as a new …

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Supplementary Figures S1-S6 from MGMT Promoter Methylation Predicts Overall Survival after Chemotherapy for 1p/19q-Codeleted Gliomas

Connor Jarrett Kinslow, Ali I. Rae, Kekoa Taparra, Prashanth Kumar et autres

Supplementary Data

Supplementary Tables S1-S3 from MGMT Promoter Methylation Predicts Overall Survival after Chemotherapy for 1p/19q-Codeleted Gliomas

Connor Jarrett Kinslow, Ali I. Rae, Kekoa Taparra, Prashanth Kumar et autres

Tables S1-S3

RADT-33. PROGNOSTIC AND PREDICTIVE EFFECT OF AGE IN MOLECULARLY-DEFINED LOWER GRADE GLIOMAS: A REPORT FROM THE PROSPECTIVE GLIOMA RESEARCH (PROGRES) DATABASE

Connor Jarrett Kinslow, Giuseppe Minniti, Paul David Brown, Michael A. Vogelbaum et autres

Abstract PURPOSE Age over 40 years is commonly regarded as a “high risk” feature and potential indication for adjuvant chemoradiotherapy for patients with lower grade glioma in most clinical practice guidelines. However, these recommendations are based on retrospective observations and their subsequent …

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EPID-25. Molecular Epidemiology of Adult Diffuse Gliomas in the United States

Connor Jarrett Kinslow, David M. DeStephano, Quinn T. Ostrom, Soumyajit Roy et autres

Abstract INTRODUCTION US cancer registries recently started collecting data on brain molecular markers, providing for the first time population-based data on the molecular epidemiology of gliomas. However, the initial release contained a significant proportion of missing data, precluding complete incidence rate estimates. …

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Anaplastic Large Cell Lymphoma of the Breast by Race and Ethnicity

Dylan K Kim, Lauren S Lowe, Alfred I. Neugut, James B. Yu et autres

Importance: The incidence rate of primary breast anaplastic large cell lymphoma (ALCL), a complication associated with breast implants, is rapidly rising in the US. Comprehensive studies on the racial and ethnic epidemiologic characteristics of ALCL in the US are lacking, despite evidence …

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Risk of Secondary Malignancy after Radiotherapy for Benign Intracranial Tumors

Hassan Mahmood, James B. Yu, David Paul Horowitz, L.A. Kachnic et autres

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Lymphomas of the Breast After Postmastectomy Implant-Based Breast Reconstruction

Connor Jarrett Kinslow, Dylan K Kim, Lauren S Lowe, Simon K. Cheng et autres

This cohort study evaluates the incidence rate of lymphomas of the breast after implant-based breast reconstruction after cancer-directed mastectomy.

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SO11. Risk of Lymphomas of the Breast Following Breast Reconstruction

Dylan K Kim, Lauren S Lowe, Christine Hsu Rohde, David Paul Horowitz et autres

PURPOSE: The US Food and Drug Administration (FDA) recently issued a safety communication for reports of various lymphomas of the breast that developed in association with breast implants and were distinct from BIA-ALCL. We investigate the risk of non-BIA-ALCL breast lymphomas in …

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