Long‐Fei Wu

Development of a Novel Risk Prediction Model for Rheumatoid Arthritis–Associated Interstitial Lung Disease (RA-ILD): A Longitudinal Study

Yu-ping Lv, Siyi Wang, Hai-ning Piao, Zheng Gong et autres

Abstract Objectives Interstitial lung disease (ILD) is one of the most common and potentially most devastating extra-articular complication of rheumatoid arthritis (RA) and is associated with substantial morbidity and mortality. However, early identification tools remain limited. This study aimed to identify plasma …

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Integrative analysis reveals synergistic regulation of Sp7 by BRD9 and Wnt/β-catenin signaling during osteogenic differentiation

Long‐Fei Wu, Lei Wang, Yan Zhuang, Yuan Luo et autres

Osteoporosis is a complex skeletal disorder characterized by low bone mineral density (BMD). Compared with classical epigenetic modifications, such as DNA methylation and histone modifications, the participation of chromatin-remodeling complexes in osteoporosis remains less explored. To identify chromatin remodeling factors causally associated …

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Epidemiology of neurological diseases in China: Key insights from the 2024 report of the National Center for Neurological Disorders

Yicong Lin, Linzi Song, Yi Tang, Xue Wang et autres

Neurological disorders pose a severe public health challenge in China, with substantial impacts on mortality, disability, and socioeconomic burden, especially in the context of population aging. This study synthesizes key findings from the China Neurological Disorders Report 2024 (compiled by the National …

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Regional concentrations of heavy metals in surface soils and risk of body pain in elderly residential population: a national cohort study in China

Bingjie Qu, Bifeng Hu, Rong Rong, Long‐Fei Wu et autres

BACKGROUND: The accumulation of heavy metals in surface soil raises significant environmental and public health concerns around the world. This study aimed to examine the relationship between exposure to heavy metals in surface soil and the risk of pain among residents. METHODS: …

gb, cn, us (code pays fourni par la source)

Association of habitual glucosamine use with risk of microvascular complications among individuals with type 2 diabetes: a prospective cohort study in UK biobank

Zi‐Jian Cheng, Yufeng Luo, Qing-yun Zhu, Yanfei Wang et autres

BACKGROUND: Glucosamine is a widely used supplement for treating osteoarthritis and joint pain. New evidence suggests a potential association between glucosamine and type 2 diabetes, inflammation and cardiometabolic risk. We aimed to prospectively evaluate the association of habitual glucosamine use with risk …

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Advanced passive daytime radiative cooling: from material selection and structural design to application towards multifunctional integration

Linhu Li, Qing Zhang, Guimin Liu, Ruidong Shi et autres

no (code pays fourni par la source)

Association between weekend warrior physical activity pattern and all-cause mortality among adults living with type 2 diabetes: a prospective cohort study from NHANES 2007 to 2018

Jinli Mahe, Ao Xu, Li Liu, Lei Hua et autres

BACKGROUND: It is uncertain whether the weekend warrior pattern is associated with all-cause mortality among adults living with type 2 diabetes. This study explored how the 'weekend warrior' physical activity (PA) pattern was associated with all-cause mortality among adults living with type …

cn, au, th, hk, us (code pays fourni par la source)

Integrative Analysis Identified rs907091 at the miRNA Binding Region of the IKZF3 Gene as a Potential Functional Variant for Rheumatoid Arthritis

Wei Xia, Long‐Fei Wu, Shu‐Feng Lei

Objective: Previous studies have identified a large number of associations between genetic variants and rheumatoid arthritis (RA), but the functional mechanisms underlying the associations are largely unknown. Methods: Based on publicly available datasets and results, we explored the functional mechanisms underlying the …

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Unraveling the relationship between high-sensitivity C-reactive protein and frailty: evidence from longitudinal cohort study and genetic analysis

Yufeng Luo, Zi‐Jian Cheng, Yanfei Wang, Xiyuan Jiang et autres

BACKGROUND: This study aimed to investigate the association of high-sensitivity C-reactive protein (hs-CRP) with incident frailty as well as its effects on pre-frailty progression and regression among middle-aged and older adults. METHODS: Based on the frailty index (FI) calculated with 41 items, …

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PKM2 is a Novel Osteoporosis-Associated Protein in Chinese

Qing Xu, Chunhui Li, Chang-Hua Tang, Xiaoli Huang et autres

Purpose:Osteoporosis is characterized by low bone mineral density (BMD) and high risk of osteoporotic fracture (OF). Peripheral blood monocytes (PBM) can differentiate into osteoclasts to resorb bone. This study was to identify PBM-expressed proteins significant for osteoporosis in Chinese Han elderly population …

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Development and validation of a risk prediction model for incident frailty in elderly patients with cardiovascular disease

Yufeng Luo, Xiyuan Jiang, Yue-ju Wang, Wenyan Ren et autres

tw, cn (code pays fourni par la source)

Association of Weekend Warrior Physical Activity Pattern with All-Cause Mortality Among Adults with Type 2 Diabetes: A Prospective Cohort Study from NHANES 2007 to 2018

Jinli Mahe, Ao Xu, Li Liu, Lei Hua et autres

au, cn, gb, us, hk (code pays fourni par la source)