Muthita Trakultivakorn

Targeted Gene Sanger Sequencing Should Remain the First-Tier Genetic Test for Children Suspected to Have the Five Common X-Linked Inborn Errors of Immunity

Koon-Wing Chan, Chung-Yin Wong, Daniel Leung, Xingtian Yang et autres

To address inborn errors of immunity (IEI) which were underdiagnosed in resource-limited regions, our centre developed and offered free genetic testing for the most common IEI by Sanger sequencing (SS) since 2001. With the establishment of The Asian Primary Immunodeficiency (APID) Network …

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Application of Flow Cytometry in the Diagnostics Pipeline of Primary Immunodeficiencies Underlying Disseminated Talaromyces marneffei Infection in HIV-Negative Children

Pamela P. W. Lee, Mongkol Lao‐Araya, Jing Yang, Koon-Wing Chan et autres

is an AIDS-defining infection in Southeast Asia and is associated with high mortality. It is rare in non-immunosuppressed individuals, especially children. Little is known about host immune response and genetic susceptibility to this endemic fungus. Genetic defects in the interferon-gamma (IFN-γ)/STAT1 signaling …

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Practical considerations of nebulized corticosteroid in children with acute asthmatic exacerbation: A consensus

Chalerat Direkwattanachai, Chalermthai Aksilp, Pantipa Chatchatee, Orathai Jirapongsananuruk et autres

BACKGROUND: Acute asthmatic exacerbation in children causes economic burdens both directly and indirectly. The GINA guideline does mention the use of inhaled or oral corticosteroids in the treatment of asthmatic exacerbation, it provides little practical guidance on the use of nebulized corticosteroid. …

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Specific IgE to honeybee venom in patients with hypersensitivity to Asian giant honeybee (Apis dorsata).

Mongkol Lao‐Araya, Dararat Dankai, Muthita Trakultivakorn

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Economic burden of asthma in Thailand.

Muthita Trakultivakorn

Asthma is an important health problems worldwide and the prevalence is increasing in most part of the world including Thailand. The prevalence of asthma in Thai children is approximately 10%. The impact of this disease on patients’ health and quality of life …

Prevalence of food allergy among preschool children in northern Thailand

Mongkol Lao‐Araya, Muthita Trakultivakorn

BACKGROUND: The epidemiology and clinical spectrum of food allergies (FA) confirmed by oral food challenge tests (OFC) in the Southeast Asian countries are limited. The aim of the present study was to examine the prevalence and characteristics of FA among preschool children …

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Allergic rhinitis and immunoglobulin deficiency in preschool children with frequent upper respiratory illness.

Sudawan Siriaksorn, Somchart Suchaitanawanit, Muthita Trakultivakorn

BACKGROUND: Frequent upper respiratory illness (URI) is a common problem in preschool children. Allergic rhinitis and immunoglobulin (Ig) deficiency are usually suspected as underlying etiologies. OBJECTIVE: To determine the prevalence of allergic rhinitis and Ig and IgG subclass deficiency in preschool children …

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Comparison of salbutamol efficacy in children--via the metered-dose inhaler (MDI) with Volumatic spacer and via the dry powder inhaler, Easyhaler, with the nebulizer--in mild to moderate asthma exacerbation: a multicenter, randomized study.

Chalerat Direkwatanachai, Jamaree Teeratakulpisarn, Somchai Suntornlohanakul, Muthita Trakultivakorn et autres

BACKGROUND: Beta(2) agonist administered via a nebulizer is the standard treatment for acute asthma exacerbation. There are some limitations for the use of nebulization. We conducted a study to determine the efficacy of salbutamol administered via the pMDI with Volumatic spacer and …

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Prevalence of Food Allergy Among Preschool Children in Northern Thailand

Mongkol Lao‐Araya, Muthita Trakultivakorn

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Air pollution-related peak expiratory flow rates among asthmatic children in Chiang Mai, Thailand

Phongtape Wiwatanadate, Muthita Trakultivakorn

The severity of air pollution in northern Thailand has long been recognized; in spite of that there have been no epidemiological studies regarding the associations between the air pollution and health effects in the area. The authors followed a cohort of 31 …

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Time Trends of the Prevalence of Asthma, Rhinitis and Eczema in Thai Children–ISAAC (International Study of Asthma and Allergies in Childhood) Phase Three

Muthita Trakultivakorn, Pasuree Sangsupawanich, Pakit Vichyanond

Using the same questionnaire as in ISAAC Phase One study conducted in 1995, the ISAAC Phase Three was carried out in Bangkok and Chiang Mai, Thailand, in 2001, among children aged 6-7 and 13-14 years. There was an increase in the prevalence …

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Allergic Rhinitis and Immunoglobulin Deficiency in Preschool Children with Frequent Upper Respiratory Illness

Sudawan Siriaksorn, Muthita Trakultivakorn, Somchart Suchaitanawanit

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