Erin D. Lewis

A Randomized, Triple-Blind, Placebo Controlled, Parallel Virtual Clinical Trial to Investigate the Efficacy of Royal Jelly Supplementation on Upper Respiratory Tract Infections in Healthy Adults

Jenalyn L Yumol, Rok Kopinč, Huda Al-Wahsh, David C Crowley et autres

Purpose: To investigate the efficacy of royal jelly (RJ) supplementation compared to placebo on upper respiratory tract infection (URTI) symptoms in healthy adults during the 2024– 2025 North American cold and flu season. Patients and Methods: One hundred healthy adults aged 18 …

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Effects of Lactiplantibacillus plantarum 299v and Lactiplantibacillus plantarum GOS42 on gastrointestinal symptoms in healthy adults with occasional constipation

Gunilla Önning, Christina S. Vegge, Caroline Montelius, Erin D. Lewis et autres

BACKGROUND The global prevalence of functional constipation is approximately 12%. It is characterized by infrequent complete spontaneous bowel movements (CSBMs), hard or lumpy stools, straining during defecation, and has a negative impact on quality of life (QoL). The probiotic strain Lactiplantibacillus plantarum …

A Randomized, Triple‐Blind, Placebo‐Controlled, Parallel Clinical Trial Investigating Safety and Efficacy of Corn Leaf Extract on Sleep Quality in a Healthy Population With Difficulty Falling or Staying Asleep

Katarina M. Doma, Abdelrahman Zamzam, David C. Crowley, Najla Guthrie et autres

ABSTRACT Difficulties falling and/or staying asleep affect over one quarter of adults in the United States. Current management strategies include prescription sleep aids. However, long‐term use is associated with serious adverse effects. Therefore, natural alternative sleep aids that may provide safer and …

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Almond Consumption on HDL Cholesterol and CVD Risk Factors in Adults with High Cholesterol: A Randomized, Comparator-Controlled Trial

Katarina M. Doma, Marc Moulin, David C. Crowley, Najla Guthrie et autres

Dietary modifications are recommended for individuals with hypercholesterolemia to reduce cardiovascular disease (CVD) risk. While almonds have been shown to improve certain CVD risk factors, the effects of almonds on high-density lipoprotein cholesterol (HDL-C) are less clear. This study aimed to determine …

A randomized, triple-blind, placebo-controlled, parallel study of the efficacy of D-mannose for urinary tract infection symptoms in women

Ruma G. Singh, Elizabeth A. Nguyen, Yongqiang Zhao, Chengliang Zhang et autres

Abstract Background Urinary tract infections (UTIs) are common infectious disorders affecting 50% of healthy women at least once during their lifetime. Antibiotic treatment for UTIs may increase the prevalence of antimicrobial resistance and side effects, highlighting the need for safe and efficacious …

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A possible role for food-based citrus bioactive compounds in bridging the gap between prevalence of diabetes and the effectiveness of current treatments

Malkanthi Evans, Erin D. Lewis, David E. Crowley, Najla Guthrie

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Efficacy of Probiotic Supplementation with Lactiplantibacillus plantarum Strains on Gastrointestinal Tract Function – A Randomized Controlled Trial

Ruma G. Singh, Fumiki Aoki, Maria Rodriguez-Palmero Seuma, Meritxell Aguiló et autres

Gastrointestinal (GI) dysfunction in older adults may be associated with gut microbiota activity or composition changes. Lactiplantibacillus plantarum strains KABP031 and KABP032 have been shown to beneficially influence the frequency of bowel movements (BMs) and nutritional status in older adults. This study …

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0967 A Randomized, Triple-blind, Placebo Controlled Trial Investigating a Standardized Corn Leaf Extract on Sleep in Healthy Adults with Sleep Difficulties

Mesfin Yimam, Qi Jia, Katarina M. Doma, Abdelrahman Zamzam et autres

Abstract Introduction Difficulties falling and/or staying asleep affects over one quarter of American adults. Current management strategies include prescription sleep aids; however, long-term use is associated with adverse effects and natural alternatives may provide safer and more effective relief. UP165, a standardized …

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A Randomized, Triple-Blind, Placebo-Controlled Clinical Trial Investigating a Corn Leaf Extract (UP165) on Sleep Quality in Healthy Adults With Sleep Difficulties

Marc Moulin, Katarina M. Doma, Abdelrahman Zamzam, David C. Crowley et autres

obtained using a validated food frequency questionnaire.Multivariable Cox proportional hazard regression models were used to calculate adjusted hazard ratios (HRs) and 95% confidence intervals (CIs).Stratified analyses by tumor site and TNM stage were performed, and restricted cubic spline were used to examine …

An open-label clinical trial to investigate the safety and efficacy of a bone broth diet on weight loss in adults with obesity

Katarina M. Doma, Marc Moulin, Huda Al‐Wahsh, Najla Guthrie et autres

Summary Background and aims Over 40% of North American adults are obese and with rates increasing, an already significant public health concern is expected to get worse. Modifiable risk factors such as poor dietary habits represent an opportunity for targeted change. The …

Association between isometric knee extensor strength at 20º and 90º measured using a hand-held dynamometer in recreationally active adults

Erin D. Lewis, David Poller, A. Puncher, E. Moor et autres

Livaux® gold kiwifruit powder consumption at 600 mg per day for 28 days increases Faecalibacterium prausnitzii numbers and decreases bloating and hydrogenotrophic species numbers in healthy individuals, consistent with slow fermentation: A randomized controlled trial

Starin McKeen, Susanne M. Henning, Erin D. Lewis, Malkanthi Evans et autres