Ariana Bruzzone

Inhibition of phosphodiesterase 4 and 7 regulates breast cancer cell proliferation

Carla Mayora Justel, Tamara Valladares, Lucia Gargiulo, Maximiliano de Sousa et autres

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Quercetin-loaded magnetic nanoparticles: a promising tool for antitumor treatment in human breast cancer cells

Silvina Tiburzi, Virginia Lezcano, Gabriel Principe, M. Schneider et autres

Quercetin (QUE) is a phytoestrogen with known antitumor properties; however, its hydrophobic nature and low bioavailability limit its efficacy as an anticancer drug. To address this, we explored loading QUE onto a non-toxic nanocarrier. This study focused on the biological activity of …

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[Barriers and facilitators in the implementation of the National Colorectal Cancer Prevention Program: a qualitative evaluation from the perspective of health personnel].

Laura Antonietti, Cecilia Sarriguren, María Eugenia Esandi, Ariana Bruzzone

INTRODUCTION: In 2013, Argentina launched a National Program for the Prevention and Early Detection of Colorectal Cancer (CRC). A decade later, the incidence of this cancer continues to rise, with low screening coverage rates and late-stage diagnoses. This study examines the barriers …

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[Effectiveness of strategies to increase adherence to colorectal cancer screening: a systematic review].

Iñaki M Dopazo Danieli, Manuel Robles, María Belén Bellando, Gonzalo Picardi et autres

INTRODUCTION: Coverage for colorectal cancer screening in Argentina is very low. The objective of this review is to assess and synthesize the evidence on the effectiveness of strategies aimed at increasing adherence to colorectal cancer screening among healthcare personnel and the general …

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[Barriers and facilitators of colorectal cancer screening access].

Yamila Schenfeld, Joel Agustín Schernenco, María Belén Bellando, Manuel Robles et autres

INTRODUCTION: Colorectal cancer (CRC) is a global health problem. In the public sector of Bahía Blanca, CRC screening is opportunistic, through the request of fecal occult blood test (FOBT). The objective of this study is to describe access to CRC screening for …

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Aislamiento y caracterización de un Diterpeno Abietano de la planta Coleus Neochilus con potente actividad antiproliferativa en una línea celular de cáncer de mama humano

Carla Mayora Justel, Tamara Valladares, Valéria Cavallaro, Ana Paula Murray et autres

Las especies del género Coleus poseen diversas aplicaciones etnobotánicas, siendo su uso más frecuente el atribuido a sus propiedades medicinales. Previamente hemos descripto el efecto antiproliferativo del extracto etanólico de C. neochilus (también conocido como boldo rastre-ro) en diferentes líneas celulares de …

The Beta2-adrenergic agonist salbutamol synergizes with paclitaxel on cell proliferation and tumor growth in triple negative breast cancer models

Martina Jabloñski, María Sol Rodríguez, Ezequiel Mariano Rivero, Carlos David Bruque et autres

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Adrenergic receptors in breast cancer

Cecilia Pérez Piñero, Ezequiel Mariano Rivero, Lucia Gargiulo, María Sol Rodríguez et autres

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Tyrosine phosphorylation differentially fine-tunes ionotropic and metabotropic responses of human α7 nicotinic acetylcholine receptor

Juan Facundo Chrestia, Ariana Bruzzone, María del Carmen Esandi, Cecilia Bouzat

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Agonist Effects of Propranolol on Non-Tumor Human Breast Cells

Lucia Gargiulo, Ezequiel Mariano Rivero, Nicolás Di Siervi, Edgardo D. Buzzi et autres

The β-blocker propranolol (PROP) has been proposed as a repurposed treatment for breast cancer. The similarity of action between β-agonists and antagonists found on breast cells encouraged us to compare PROP and isoproterenol (ISO, agonist) signaling pathways on a human breast cell …

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Prognostic significance of α‐ and β2‐adrenoceptor gene expression in breast cancer patients

Ezequiel Mariano Rivero, Leandro Marcelo Martinez, Carlos David Bruque, Lucia Gargiulo et autres

Aims Breast cancer is the most frequently diagnosed and leading cause of cancer death among women worldwide. It was classified within molecular intrinsic subtypes: luminal A, luminal B, human epidermal growth factor receptor 2‐enriched and basal‐like. Epinephrine and norepinephrine, released during stress, …

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Prevención del cáncer de cuello uterino

Isabel Alicia Lüthy, Ariana Bruzzone

A nivel mundial, el cáncer de cuello uterino es una neoplasia indicadora de disparidad social, con prevalencia en países en vías de desarrollo y poblaciones con escaso acceso a los servicios de salud. Según datos de la IARC (International Agency for Research …