Áurea Simón‐Soro

Human Tooth as a Fungal Niche: Candida albicans Traits in Dental Plaque Isolates

Dongyeop Kim, Áurea Simón‐Soro, Jiyao Li, Rohan S. Wakade et autres

Candida albicans, a fungus typically found in the mucosal niche, is frequently detected in biofilms formed on teeth (dental plaque) of toddlers with severe childhood caries, a global public health problem that causes rampant tooth decay. However, knowledge about fungal traits on …

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Salivary estrone and estradiol are associated with oral microbiome profiles in aging women

Maria J. Rus, Maria Nieto, Hyo-Jung Oh, H.-J. Yoo et autres

Objectives To explore whether salivary estrogens (estrone and estradiol) are associated with oral microbiome composition in aging women, and to assess the oral cavity as a potential sentinel of systemic hormonal changes during midlife.Materials and methods Cross-sectional study including 30 women aged …

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Lung transplant for CF: Low lung bacterial burden and immune mediators in year one associate with CLAD development

Samantha A. Whiteside, John E. McGinniss, Rebecca A. Deek, Carter Merenstein et autres

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Dental Caries Status in Postmenopausal Women: Systematic Review and Meta-Analysis

Victoria Areal‐Quecuty, Juan José Segura-Egea, Áurea Simón‐Soro, María León‐López et autres

Background: Dental caries is one of the most common oral infections observed worldwide. It is defined as a multifactorial dynamic disease-causing mineral loss of dental hard tissue, which is identified by the caries lesion. Treatment of the caries lesion involves filling the …

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Dental Caries Status in Postmenopausal Women: Systematic Review and Meta-Analysis

Victoria Areal‐Quecuty, Juan José Segura-Egea, Áurea Simón‐Soro, María León‐López et autres

Background. Dental caries is one of the most common oral infections observed worldwide. It is defined as a multifactorial dynamic disease-causing mineral loss of dental hard tissue, which is identified by the caries lesion. Treatment of caries lesion involves filling the cavity …

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Menopausal shift on women’s health and microbial niches

Maria J. Rus, Victoria Areal‐Quecuty, Daniel María Lubián López, Áurea Simón‐Soro

Menopause marks a key milestone in women’s aging, triggering hormonal, histological, and microbiome changes. This review explores how hormonal shifts during menopause alter the microbiome’s composition, affecting oral, intestinal, and urogenital communities, potentially leading to disease. The microbial metabolism of sex hormones …

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Hormonal Environment Shapes the Oral Microbiome

Maria J. Rus, Flávio Duarte Faria, Áurea Simón‐Soro

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Role of Saliva in Oral Biofilm Models

Carolina de Barros Morais Cardoso, Cristiane Cantiga da Silva, Áurea Simón‐Soro

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Ferumoxytol nanozymes effectively target chronic biofilm infections in apical periodontitis

Alaa Babeer, Yuan Liu, Zhi Feng Ren, Zhenting Xiang et autres

Bacterial biofilms are pervasive and recalcitrant to current antimicrobials, causing numerous infections. Iron oxide nanozymes, including an FDA-approved formulation, ferumoxytol (FMX), show potential against biofilm infections via catalytic activation of hydrogen peroxide (H2O2). However, clinical evidence regarding the efficacy and therapeutic mechanisms …

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Distinct Gastrointestinal and Reproductive Microbial Patterns in Female Holobiont of Infertility

Ana Teresa Marcos, Maria J. Rus, Victoria Areal‐Quecuty, Áurea Simón‐Soro et autres

The microbiota is in symbiosis with the human body as a holobiont. Infertility conditions affect the female reproductive tract (FRT) and its resident microbiota. However, a disturbance in homeostasis could influence the FRT and other distal body sites, such as the gastrointestinal …

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Data Mining Techniques for Endometriosis Detection in a Data-Scarce Medical Dataset

Pablo Caballero, Luis González Abril, Juan Antonio Ortega, Áurea Simón‐Soro

Endometriosis (EM) is a chronic inflammatory estrogen-dependent disorder that affects 10% of women worldwide. It affects the female reproductive tract and its resident microbiota, as well as distal body sites that can serve as surrogate markers of EM. Currently, no single definitive …

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Oral Health Phenotype of Postmenopausal Women Using AI

Rodion Kraft, Juan Antonio Ortega, Áurea Simón‐Soro, Natividad Martínez Madrid et autres

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