Li Wan

Biochemical characterization of UDP-glycosyltransferase UGT73C21 from Barbarea vulgaris for efficient conversion of protopanaxadiol to ginsenoside Rh2

Fan Xu, Yuting Liao, Yulei Zhang, Nanyu Han et autres

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Identification and characterization of a novel α-L-fucosidase from Desertivirga arenae for efficient L-fucose biosynthesis in metabolically engineered Escherichia coli

Jiawei Meng, Aiguo Li, Zhen Lu, Wenli Zhang et autres

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Influence of Qufeng Juanyin Decoction （祛风蠲饮汤） on exhaled breath condensate metabolites in children with bronchial asthma of cold wheezing syndrome

Huilin Liang, Jinlan PENG, Li Wan

目的 观察祛风蠲饮汤治疗后支气管哮喘寒哮证患儿呼气冷凝液中的代谢物的变化，探讨祛风蠲饮汤对支气管哮喘寒哮证的调节机制。 方法 收集哮喘寒哮症患儿在祛风蠲饮汤治疗前后以及健康儿童的呼气冷凝液样本，采用超高效液相色谱串联质谱（LC-MS/MS）技术对样本进行分析。通过正交偏最小二乘判别分析（OPLS-DA），筛选出呼气冷凝液中的差异代谢物及相关代谢通路。 结果 健康儿童、支气管哮喘寒哮证患儿、祛风蠲饮汤治疗后的呼气冷凝液能够得到明显区分，共鉴定出39个潜在的呼气冷凝液差异代谢物（VIP>1，Fold Change≥1.2或≤0.83，P<0.05） 。其中，琥珀酸、己二酸和对苯二甲酸在治疗前呈上升趋势，治疗后下降。乙醛酸盐和二羧酸盐代谢及丙氨酸、天冬氨酸和谷氨酸代谢两条代谢通路中的差异代谢物在治疗前表达趋势上调，而在祛风蠲饮汤治疗后下调。 结论 祛风蠲饮汤可使支气管哮喘寒哮证儿童的异常能量代谢和氨基酸代谢有所恢复，可能是通过对机体内3个潜在的生物标志物和代谢通路的调节达到治疗的目的。

Investigations on endwall film cooling of slot and discrete film holes with different diameters

Mengyu Shang, Li Wan, Ding Luo, Wenbin Chen et autres

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Mechanistic Insights into Flood Pulse-Induced Ecological Benefits and a Balanced Eco-Risk Assessment Framework

Yujie Cai, Yuqing Chang, Xinhua Zhang, Li Wan et autres

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The influence of impingement angle on heat transfer at leading edge of blades in a rotating state

Xuejiao Zhang, Ruquan You, Haiwang Li, Heming Han et autres

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Real-Time Monitoring of Tunnel Secondary Lining Void: Methodology and Device

Shuai Shao, Li Wan, Yimin Wu, Helin Fu et autres

The compactness of the secondary lining in tunnels is crucial for the overall stability and durability of the structures. This study aims to thoroughly analyze the causes and formation mechanisms of voids in the secondary lining, providing scientific guidance for construction and …

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Experimental and numerical investigation in rotating double-wall channel with side outflow

Wenbin He, Li Wan, Ding Luo, Wenbin Chen et autres

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Electronic structure modulation and nonlinear bandgap evolution of (001) surfaces in layered 2D APbI₃ (A=MA, FA) perovskites

Li Wan, Mohamad Fariz Mohamad Taib, Mohamad Hafiz Mamat, Muhamad Kamil Yaakob

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Plasma lipids, amino acids, and their metabolic pathways as potential biomarkers for differential diagnosis of cold and heat syndrome asthma in children: a preliminary study

Yi Sun, Lianzhan Huang, Zhengguang Chen, Dong Cui et autres

Background: Childhood asthma has a significant effect on growth and development. Traditional Chinese Medicine (TCM) has notable advantages in asthma treatment; however, a modern scientific basis for the differentiation of cold and heat syndromes in asthma remains lacking. Methods: This study employed …

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Structural Design of Micro Heat Pipe Array Temperature Difference Power Generation System

Wei Wang, Li Wan

The article applies both semiconductor thermoelectric power generation technology and micro heat pipe array heat dissipation technology to the utilization of waste heat from high heat flux density devices, achieving waste heat recovery and power generation from high heat flux density devices. …

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High P-doped hollow carbon spheres for rapid sodium storage and ultra-long cycling life

Li Wan, Yiwei Liu, Yiting Zhao, Zhenhua Wang et autres

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