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Profil bibliographique

Rajeshwari Mahalingam

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

11Publications signalées
177Citations signalées
1Affiliations récentes

Les institutions déclarées

Les domaines associés

Tuberous Sclerosis Complex ResearchEpilepsy research and treatmentFunctional Brain Connectivity StudiesMarine and coastal plant biologyInternational Maritime Law Issues

Les publications récentes

2023 article OpenAlex

PRAX-562-101: A Phase 1 Trial Evaluating the Safety, Tolerability, Pharmacokinetics and Food Effect of PRAX-562 in Healthy Volunteers (P8-9.011)

Brian Pfister, Rajeshwari Mahalingam, Michael Oldham, Dharit Patel et autres

We report findings from a first-in-human trial evaluating safety, tolerability, and pharmacokinetics (PK) of single and multiple ascending doses of PRAX-562, as well as the effect of food on PK of a single dose in healthy adults.

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1 citation Neurology
2023 article OpenAlex

PRAX-562-102: A Phase 1 Trial Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PRAX-562 in Healthy Volunteers (P4-9.011)

Rajeshwari Mahalingam, Michael Oldham, Corey B. Puryear, Prashant N. Bansal et autres

Objective: We report findings from a Phase 1 clinical trial characterizing the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of PRAX-562 in healthy adults. Background: PRAX-562 is a next-generation sodium channel blocker with a unique profile expected to translate to a wider …

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3 citations Neurology
Accès ouvert 2018 article OpenAlex

Everolimus for treatment-refractory seizures in TSC

David Neal Franz, John A. Lawson, Zühal Yapıcı, Hiroko Ikeda et autres

BACKGROUND: EXamining everolimus In a Study of Tuberous sclerosis 3 (EXIST-3) demonstrated significantly reduced seizure frequency (SF) with everolimus vs placebo. In this study, we evaluate the long-term efficacy and safety of everolimus for tuberous sclerosis complex (TSC)-associated treatment-refractory seizures. METHODS: After …

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111 citations Neurology Clinical Practice

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