José Antonio Plaza

Abstract B038: Inflammatory spatial niches distinguished by antigen presentation and interferon response programs explain the high immune response rate of desmoplastic melanoma: Comparison of biopsies from SWOG S1512 and S1616

Daniel Chen, Amanda Truong, Nataly Naser Al Deen, Cynthia R. Gonzalez et autres

Abstract Background: Immune checkpoint blockade (ICB) has revolutionized cancer treatment by inducing remission in patients who were refractory to traditional therapies. By removing the brakes from anti-tumor immune cells, ICB has led to remarkable responses in several cancer types. However, these responses …

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Neoadjuvant PD-1 blockade in surgically resectable desmoplastic melanoma: cohort A of the phase 2 SWOG S1512 trial

Kari Lynn Kendra, Shay L. Bellasea, Zeynep Eroglu, Siwen Hu-Lieskovan et autres

The phase 2 SWOG S1512 trial ( NCT02775851 ) was designed to evaluate the response to pembrolizumab (anti-PD-1) in individuals with desmoplastic melanoma. Here we report the results of cohort A of the trial, evaluating the pathological complete response (pCR) rate of …

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Distinctive genomic features of hydroa vacciniforme lymphoproliferative disorder in Latin American patients: A multicenter multi-omics study

Aleksander Łuniewski, Margaret E. Moore, Eli S. Williams, Liqiang Xi et autres

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Anti-PD-1 therapy in unresectable desmoplastic melanoma: the phase 2 SWOG S1512 trial

Kari Lynn Kendra, Shay L. Bellasea, Zeynep Eroglu, Siwen Hu‐Lieskovan et autres

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Primary Eruptive Cutaneous Squamous Cell Carcinomas in a Patient with Metastatic Rectal Squamous Cell Carcinoma

Saba Shafi, Anne M. Noonan, Kenneth L. Pitter, José Antonio Plaza et autres

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Spontaneous Pneumothorax in a Patient with Isolated Cardiac Sarcoidosis

Patrick J. Kramer, Arindam Singha, José Antonio Plaza, Elliott D. Crouser

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Abstract PR006: High melanoma-specific survival in patients with desmoplastic melanoma treated with single agent anti-PD-1 in SWOG S1512

Kari Lynn Kendra, Shay L. Bellasea, Zeynep Eroglu, Siwen Hu‐Lieskovan et autres

Abstract Desmoplastic melanoma is a rare subtype of cutaneous melanoma defined by extensive fibrosis (desmoplasia), and at the same time has pre-existing immune infiltrates and a high tumor mutational burden (TMB) resulting from exposure to ultraviolet (UV) light, which we hypothesized may …

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Autoimmune Genital Dermatoses

Zaynah Awethe, David Gustafson, José Antonio Plaza, Jessica A. Kaffenberger

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Inflammatory Genital Dermatoses

Saksha Krishnan, David Gustafson, José Antonio Plaza, Brittany Dulmage

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Ulcerative Genital Dermatoses

Zaynah Awethe, David Gustafson, José Antonio Plaza, Jessica A. Kaffenberger

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Genital Neoplasms

Ruth Zagales, Benjamin Rushing, David Gustafson, José Antonio Plaza et autres

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Silicon oxide microchips functionalized with fluorescent probes for quantitative real-time glutathione sensing in living cells

Saman Bagherpour, Patricia Vázquez, Marta Duch, Juan Pablo Agusil et autres

experiments in HeLa cells reveal both SOμC-Bdpy1 and SOμC-Bdpy2 were internalized in living cells, showing SOμC-Bdpy2 more reliable results (due to its less time dependency) for quantifying intracellular GSH. Remarkably, the intracellular GSH measurement was monitored by SOμC-Bdpy2 for 48 h, indicating …

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