Accès ouvert
2023
article
OpenAlex
Igor Dolgalev, Hua Zhou, Nina Murrell, Hortense Le et autres
Approximately 30% of early-stage lung adenocarcinoma patients present with disease progression after successful surgical resection. Despite efforts of mapping the genetic landscape, there has been limited success in discovering predictive biomarkers of disease outcomes. Here we performed a systematic multi-omic assessment of …
us, no
(code pays fourni par la source)
Accès ouvert
2022
preprint
OpenAlex
Igor Dolgalev, Hua Zhou, Nina Shenker-Tauris, Hortense Le et autres
Abstract Early-stage lung adenocarcinoma is typically treated by surgical resection of the tumor. While in the majority of cases surgery can lead to cure, approximately 30% of patients progress. Despite intense efforts to map the genetic landscape of early-stage lung tumors, there …
us
(code pays fourni par la source)
2013
conference-abstract
OpenAlex
Dylan J. Johnson, Lily I. Pao, Salim Dhanji, Kiichi Murakami et autres
Abstract The tyrosine phosphatase Shp1 is expressed ubiquitously in hematopoietic cells and is generally viewed as a negative regulator. Null mutations in Ptpn6, which encodes Shp1, result in the motheaten phenotype, characterized by widespread inflammation that causes death by 3-4 weeks of …
ca, us
(code pays fourni par la source)