High-throughput evaluation of novel WRN inhibitors
Haiyan Xu, R.L. Palte, Meredith M. Rickard, Soon Woo Kwon et autres
2 citationsSLAS DISCOVERY
Indu Bharathan
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7Publications signalées
212Citations signalées
1Affiliations récentes
Institutions déclarées
Domaines associés
Tryptophan and brain disordersPharmacogenetics and Drug MetabolismPharmacological Receptor Mechanisms and EffectsProtein Kinase Regulation and GTPase SignalingCannabis and Cannabinoid Research
Publications récentes
Discovery of MK-1084: An Orally Bioavailable and Low-Dose KRAS G12C Inhibitor
Xiaoshen Ma, David L. Sloman, Ruchia Duggal, Kenneth D. Anderson et autres
40 citationsJournal of Medicinal Chemistry
Oxetane Promise Delivered: Discovery of Long-Acting IDO1 Inhibitors Suitable for Q3W Oral or Parenteral Dosing
Derun Li, David L. Sloman, Abdelghani Achab, Hua Zhou et autres
20 citationsJournal of Medicinal Chemistry
Utilization of Metabolite Identification and Structural Data to Guide Design of Low-Dose IDO1 Inhibitors
Brett A. Hopkins, Hongjun Zhang, Indu Bharathan, Derun Li et autres
9 citationsACS Medicinal Chemistry Letters
Carbamate and N-Pyrimidine Mitigate Amide Hydrolysis: Structure-Based Drug Design of Tetrahydroquinoline IDO1 Inhibitors
Derun Li, Yongqi Deng, Abdelghani Achab, Indu Bharathan et autres
27 citationsACS Medicinal Chemistry Letters
Sulfonyl Fluoride Inhibitors of Fatty Acid Amide Hydrolase
Shakiru O. Alapafuja, Spyros P. Nikas, Indu Bharathan, Vidyanand G. Shukla et autres
58 citationsJournal of Medicinal Chemistry
Discovery of a Potent and Orally Bioavailable Benzolactam-Derived Inhibitor of Polo-Like Kinase 1 (MLN0905)
Matthew O. Duffey, Tricia J. Vos, Ruth Adams, Jennifer Alley et autres
56 citationsJournal of Medicinal Chemistry
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