Anthony Obrzut

Rcope: Tools to Cope with Endogeneity Problems

Anthony Obrzut, Yi Qian, Hui Xie

Researchers across disciplines often face biased regression model estimates due to endogenous regressors correlated with the error term. Traditional solutions require instrumental variables (IVs), which are often difficult to find and validate. This package provides flexible, alternative IV-free methods using copulas, as …

Promoting mental well-being among secondary school students in Vietnam using the Y-MIND app: A protocol for a hybrid type 2, sequence pre-post, quasi-experimental study

Jill Murphy, Vu Cong Nguyen, Linh Dang, Hui Wen Xie et autres

Youth mental health is recognized as an urgent priority worldwide. Life skills education and self-management skills delivered at the population level are evidence-based approaches to promote mental well-being and resilience among youth and digital technologies are identified as promising approaches for delivering …

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ABS0847 RETROSPECTIVE SINGLE-CENTRE ANALYSIS OF SURVIVAL AND SAFETY SIGNALS IN AUTOIMMUNE RHEUMATIC DISEASE PATIENTS UNDERGOING LUNG TRANSPLANTATION

Faye A. H. Cooles, Anthony Obrzut, Na Lu, R. Levy et autres

Background: Lung transplant is increasingly offered for severe cardiopulmonary disease in autoimmune rheumatic diseases (ARDs). Patients frequently have extrapulmonary manifestations requiring immunosuppression, but how this affects clinical trajectory post-transplant is unclear. Objectives: Our study objectives were to compare complications post-transplant in people …

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OP0182 BASELINE IMMUNOSUPPRESSION AND CANCER SURVIVAL IN PATIENTS WITH PRE-EXISTING RHEUMATIC DISEASE TREATED WITH IMMUNE CHECKPOINT INHIBITORS: DATA FROM THE CANADIAN RESEARCH GROUP OF RHEUMATOLOGY IN IMMUNO-ONCOLOGY (CANRIO)

Michael A. Beckett, Carrie Ye, Marie Hudson, Janet Roberts et autres

Background: Immune checkpoint inhibitors (ICI) have revolutionized cancer outcomes, but their optimal use in patients with pre-existing rheumatic disease (PRD) remains largely unknown. There is controversial data on optimal management of baseline immunosuppression (IS) including steroids and disease-modifying antirheumatic drugs (DMARDs), use …

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Effect of Age on Rheumatic Immune-Related Adverse Events: Experience From the Canadian Research Group of Rheumatology in Immuno-Oncology (CanRIO)

Jenny Xiaoyu Li, Marie Hudson, Carrie Ye, Janet Roberts et autres

Objective Immune checkpoint inhibitors (ICIs) have revolutionized cancer outcomes but are limited by immune-related adverse events (irAEs), including rheumatic irAEs (Rh-irAEs). Aging is associated with increased inflammation, referred to as "inflammaging." In this study, we explore the effect of age on severity, …

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Tofacitinib therapy in refractory inflammatory myositis: a retrospective cohort study of 41 patients

Madelaine Beckett, Julia Tan, Evelyne Bonnardeaux, Jan Peter Dutz et autres

OBJECTIVES: To evaluate the efficacy and safety of tofacitinib in treatment-refractory inflammatory myositis in a real-world clinical setting. METHODS: All patients with refractory inflammatory myositis treated with tofacitinib from a single urban centre in Vancouver, British Columbia, Canada, were included from June …

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[Combined action of ethanol, acetylcholine and catecholamine on the organic temperature of rats acclimatized to a low temperature].

Robert P. Molenda, Anthony Obrzut

[Combined effect of acetylcholine, chlorpromazine, reserpine, atropine, dihydroergotamine and ethanol on organ temperature].

Robert P. Molenda, Anthony Obrzut

[Combined effect of chlorpromazine, acetylcholine and catecholamines on the organ temperature in cold-acclimatized rats].

Robert P. Molenda, Anthony Obrzut

[Relationship between beta lipoprotein concentration and the activity of the fibrinolytic system in arteriosclerosis and in postpartum].

J Musiatowicz, Z Skrzydlewski, Anthony Obrzut

[Anterior tibial syndrome after injury of the femoral artery].

J Matwijewicz, Anthony Obrzut

[Novocain-histamine iontophoresis in the treatment of obliterative artheriosclerosis of the lower limbs].

J Darewicz, Anthony Obrzut