Kornélia Bodó

Fusion Inhibition of Zika Virus Entry by a Teicoplanin Pseudoaglycone Derivative with Broad Antiviral Activity

Zoltán Kopasz, Ilona Bereczki, Krisztina Leiner, Henrietta Papp et autres

Background/Objectives: The lack of effective antiviral therapies for many viral infections highlights the need for the development of new antiviral agents. The broad antiviral effects of glycopeptide antibiotics (GPAs) and their derivatives have been previously described. In our studies, we investigated the …

hu (code pays fourni par la source)

Detection and Phylogenetic Characterization of Canine Distemper Virus from a Red Fox in Hungary

Dominik Szieber, Ágota Ábrahám, Krisztián Bànyai, Péter Malik et autres

Canine distemper virus (CDV) affects both domestic and wild carnivores and is associated with a high mortality rate. The virus can cross species barriers, infecting a wide range of mammals, which raises concerns for both wildlife conservation and domestic animal health. During …

hu (code pays fourni par la source)

Canine distemper virus surveillance and sequencing in invasive feral American mink (Neogale vison) in Poland

Zsófia Lanszki, József Lanszki, Gábor Kemenesi, Ágota Ábrahám et autres

Abstract Canine distemper virus (CDV) is a significant pathogen with high mortality rate affecting carnivore species worldwide, including both wild and farmed mink populations. Invasive species have been implicated in the spread of CDV, potentially facilitating viral spillover into new populations and …

hu, pl (code pays fourni par la source)

Sindbis Virus–Host Interactions in Human Neuroblastoma Cells: Implications for Viral Pathogenesis and Replication

Kornélia Bodó, Zoltán Kopasz, Viktória Nyári, Krisztina Leiner et autres

Sindbis virus (SINV) is a mosquito-borne alphavirus capable of causing neurological and immunological symptoms in humans, yet its effects on neural/immune systems remain insufficiently characterized. This study aimed to examine SINV replication, UV-C light inactivation, apoptosis induction, and immune gene modulation in …

hu (code pays fourni par la source)

Cervids as a Promising Pillar of an Integrated Surveillance System for Emerging Infectious Diseases in Hungary: A Pilot Study

István Lakatos, Péter Malik, Kornélia Bodó, Zsuzsanna Szőke et autres

Wildlife serves as a significant reservoir for various pathogens transmissible to domestic animals and humans. Vector-borne diseases represent an increasing concern in Europe, affecting both animal and human health. This pilot study investigated the circulation of endemic and emerging vector-borne viruses in …

hu (code pays fourni par la source)

UV-Inactivated Zika Virus Retains Cellular Entry Capability: Enabling a Multitude of Downstream Applications

Mr Zoltán Kopasz, Dr Roland Hetényi, Dr Dániel Hanna, Kornélia Bodó et autres

AMR can contribute to reducing the burden of infectious diseases more so in limited resource settings.

Synergistic effects of memantine and alpha7 nicotinic acetylcholine receptor agonist PHA-543613 to improve memory of aged rats

Nóra Bruszt, Zsolt Kristóf Bali, Lili Veronika Nagy, Kornélia Bodó et autres

BACKGROUND: Combination treatments based on pharmacological interactions at α7 nicotinic acetylcholine receptors (nAChRs) are promising therapeutic approaches for neurocognitive disorders. METHODS: Here, we tested the cognitive efficacy of combinations of memantine with an α7 nAChR-selective agonist (PHA-543613) in naturally aged rats. Age-related …

fr, cz, hu (code pays fourni par la source)

A novel beta-catenin homologue from the earthworm Eisenia andrei: Identification and characterization during embryonic development, segment regeneration, and immune response

Kornélia Bodó, Ákos Boros, Gréta Tolnai, Éva Rumpler et autres

Evolutionarily, Wnt/β-catenin signaling is well-conserved and supports several key cell-biological processes ( e.g. adhesion and proliferation). Its crucial component, β-catenin, has been described in several organisms, however, its identification and characterization are notably lacking in annelid earthworms. Here, we report a novel …

hu, gb (code pays fourni par la source)

Occurrence of Recombinant Canine Coronavirus, Picodicistrovirus, and Circovirus in Red Foxes ( Vulpes vulpes ) Implies Frequent Virus Transmission Events Among Carnivores

Enikő Fehér, Gábor Kemenesi, Tamás Görföl, Yasmine Wazzani et autres

Although their pathogenicity is most often unclear, some canine viruses have been found to infect carnivores other than dogs. This study relies on the surveillance of coronaviruses in 206 saliva and fecal samples of huntable, sympatric canid and mustelid species captured in …

hu (code pays fourni par la source)

Novel Semisynthetic Glycopeptide Antibiotics with Antiviral Activity Against Zika Virus and Other Emerging Viruses

Zoltán Kopasz, Ilona Bereczki, Krisztina Leiner, Henrietta Papp et autres

Increased brain cytokine level associated impairment of vigilance and memory in aged rats can be alleviated by alpha7 nicotinic acetylcholine receptor agonist treatment

Zsolt Kristóf Bali, Lili Veronika Nagy, Nóra Bruszt, Kornélia Bodó et autres

Age-related neurocognitive disorders are common problems in developed societies. Aging not only affects memory processes, but may also disturb attention, vigilance, and other executive functions. In the present study, we aimed to investigate age-related cognitive deficits in rats and associated molecular alterations …

hu (code pays fourni par la source)

Baromfi-immunglobulinok lehetséges alkalmazásai a mikotoxin-környezetterhelések és a humánérintettség fókuszában

Kornélia Bodó, György Nagyéri, Zsófia Molnár, Levente Sára et autres

In addition to their role, immunoglobulins can be used in animal and human diagnostic (immunoassay-based) measurements, prophylaxis and (immuno)therapy. For these purposes, today's "alternative" that is advantageous from an animal ethical point of view is the bird immunoglobulin Y isolated from egg …

hu (code pays fourni par la source)