Sai Krupa Das

Global external validation of fat mass prediction models for adults

Lucinda Archer, Aisha Alsaqabi, Dina Ibrahim, Noor Al-Zahraa Safar et autres

Several models using weight, height and demographic variables to estimate adult fat mass (FM) have shown promising performance but require external validation within new independent settings. Here we evaluated the performance of these models globally, using data from the International Atomic Energy …

gb, kw, us, ch, Afrique du Sud, nl, cn, jp, th, in, se, au, qa, fi, hk, de, at (code pays fourni par la source)

Biological Pathways of Strength Preservation During Calorie Restriction‐Induced Weight Loss Among Adults Without Obesity

Nadia Moore, Akshay Bareja, Leanna M. Ross, Katherine A. Collins et autres

OBJECTIVE: Weight loss is often pursued to improve cardiometabolic health and quality of life. However, weight loss can lead to reductions in lean soft tissue mass and strength, compromising body composition and functional ability. Thus, identifying molecular predictors of muscular strength preservation …

us (code pays fourni par la source)

Protein Intake Pattern and Its Association With Body Composition Among Adults Engaged in Weight Management

Tsz Kiu Chui, Lauren A. Fowler, Katie M. Ellison, Christopher D. Coleman et autres

Objectives: It has been hypothesized that evenly distributing daily intake of dietary protein intake during weight loss may improve body composition. This secondary analysis assessed whether daily protein intake patterns were associated with body composition in adults engaged in weight management.

us, no (code pays fourni par la source)

Beyond the Individual: How Social Support and Perceived Food Environment Relate to Weight Status in the International Weight Control Registry

Rawan AlSarraf, James Friedman, Tsz Kiu Chui, Drew Sayer et autres

Response to caution in interpreting the role of physical activity in weight loss maintenance among people with physical disabilities

Julianne G. Clina, R. Drew Sayer, James E. Friedman, Tsz Kiu Chui et autres

us (code pays fourni par la source)

Reply to Z Yu and F Qin

Diana M Thomas, Rodolphe Barrangou, Sharon I. Kirkpatrick, Becca BR Jablonski et autres

us, ca (code pays fourni par la source)

CALERIE™ Legacy Study: Design of the Longitudinal Follow-Up Study of Participants in the CALERIE™ 2 Trial

Susan Racette, L M Redman, Kim Huffman, Sai Krupa Das

Calorie restriction (CR), defined as a reduction in calorie intake without compromising nutrient status, directly targets the biology of aging, thereby delaying the onset and slowing the progression of age-related diseases. CR is a geroprotective strategy to extend healthspan, which is the …

us (code pays fourni par la source)

Metabolic Adaptations to Caloric Restriction: Time- and Group-Dependent Metabolomic Signatures from the CALERIE™ Trial

Melissa C. Orenduff, Emily K. Woolf, Ruiqi Zhang, Daniel W. Belsky et autres

us (code pays fourni par la source)

Quadriceps mitochondrial DNA quantity, quality, and gene expression after 2 years of calorie restriction: exploratory results from the CALERIE trial

Jayanta K. Das, Yu Zhang, Leanne M. Redman, Corby K. Martin et autres

Abstract The Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy (CALERIE)™ trial was a randomized, 2-year controlled trial of caloric restriction (CR) versus an ad libitum (AL) control condition in nonobese humans. We performed exploratory analyses of muscle mitochondrial DNA …

us, ca (code pays fourni par la source)

Use of Machine Learning to Identify Determinants of Habitual-Preformed Water Intake

Emma J. Stinson, Ethan Collins, Tomás Cabeza de Baca, Marci E. Gluck et autres

BACKGROUND: Water intake is vital for health, yet the determinants of preformed water consumption in adults are poorly understood. OBJECTIVES: This study aimed to apply machine learning (ML) models to identify factors associated with preformed water intake, defined as water ingestion from …

us (code pays fourni par la source)

Effect of 2-Year Caloric Restriction in the Absence of Malnutrition on Indicators of Anemia, Iron Status, and Hepcidin in Healthy Adults: A Randomized Clinical Trial

Cory Dugan, Sai Krupa Das, Susan B. Racette, Corby K. Martin et autres

BACKGROUND: Caloric restriction (CR) is a promising nutritional intervention for improving metabolic and age-related health outcomes, but its long-term effects on hematologic health remain unclear. Clarifying how prolonged CR affects anemia risk and iron status is essential for evaluating its long-term safety …

us (code pays fourni par la source)

Metabolic Adaptations to Long-Term Caloric Restriction: Principal Components Analysis of Mass-Spectrometry Metabolomics from the CALERIE™ Phase 2 Trial

Melissa C. Orenduff, Emily K. Woolf, Ruiqi Zhang, Daniel W Belsky et autres

ABSTRACT Background Caloric restriction (CR) improves markers of biological aging, yet long-term effects on the human metabolome remain unclear. Objective This study examined the effects of CR (2 years) in healthy adults without obesity on circulating metabolites linked to aging and metabolic …

us (code pays fourni par la source)