Allan Kalungi

Risk factors for major depressive disorder among adults recruited from hospital settings in Uganda, Kenya, Ethiopia and South Africa

Allan Kalungi, Wilber Ssembajjwe, Kester B. B. Tindi, Emmanuel K. Mwesiga et autres

Abstract Major depressive disorder (MDD) significantly contributes to the mental health burden in Africa, requiring insights into prevalence and risk factors to inform culturally responsive care. This study assessed current and lifetime MDD prevalence and associated factors among 7,073 adults from hospital …

gb, Ouganda, us, Kenya, Éthiopie, Afrique du Sud (code pays fourni par la source)

Psychiatric Genetic Research in Africa

Allan Kalungi, Jared G. Maina, Sylvanus Toikumo, Lukoye Atwoli

Psychiatric disorders are a leading cause of global disease burden, with the burden in Africa growing yet remaining largely under-recognized and under-addressed. Although there is mounting evidence for a genetic contribution to psychiatric disorders, African populations remain largely underrepresented in global psychiatric …

Impact of African-enriched GATM regulatory variants on creatinine-derived estimated glomerular filtration rate

Olivia Gray, Laura Yerges-Armstrong, Stephane E. Castel, Jean‐Tristan Brandenburg et autres

INTRODUCTION: Serum creatinine is a commonly used biomarker for estimating glomerular filtration rate (eGFR), but is influenced by determinants unrelated to kidney function, including muscle mass, age, sex, diet, and genetic variation. Biological drivers of persistent eGFR bias in African ancestry populations …

us, Afrique du Sud, Ouganda, gb, dk, Malawi (code pays fourni par la source)

Cultural adaptation of the New Forest Parenting Program (NFPP) for ADHD in HIV-infected children in Uganda: a feasibility and pilot investigation

Richard Mpango, Wilber Ssembajjwe, Allan Kalungi, Fred M. Ssewamala et autres

BACKGROUND: Attention-Deficit/Hyperactivity Disorder (ADHD) is highly prevalent among children and adolescents living with HIV (CA-HIV) in sub-Saharan Africa. In Uganda, the estimated prevalence of ADHD among CA-HIV is 25.5% (95% CI: 19.8-31.8). Despite this, there are no established interventions targeting ADHD in …

us, Ouganda (code pays fourni par la source)

PATIENT PATHWAYS TO UGANDA’S FIRST SPECIALISED EARLY INTERVENTION IN PSYCHOSIS SERVICE AND RELATION TO THEIR CLINICAL OUTCOMES

Emmanuel Kiiza Mwesiga, Wilber Ssembajjwe, Rossette Immy Ndigamanya, Sophia Balinga et autres

Background: Early Intervention for Psychosis Services (EIPS) enhance outcomes for individuals experiencing their first episode of psychosis (FEP). However, in low-resource settings, there is limited knowledge about i) the pathways patients take to access EIPS, ii) the proportion and factors associated with …

Ouganda, us (code pays fourni par la source)

Associations between PTSD and psychotic symptoms: A network analysis of patients with psychotic disorders in Uganda

Hanseul Cho, Woohyung Lee, Hyungjun Park, Anne Stevenson et autres

Introduction: Individuals with psychosis often endorse a history of trauma, yet the symptom-level interplay between trauma-related and psychotic symptoms is understudied globally and largely absent in Sub-Saharan Africa. We used network analysis to examine associations within and between these domains. Methods: We …

us, kr, sg, Afrique du Sud, Ouganda, gb, de, in (code pays fourni par la source)

KidneyGenAfrica multi-cohort Genome-wide association study and polygenic prediction of kidney function in 110,000 Africans

Abram Bunya Kamiza, Tinashe Chikowore, Guanjie Chen, Oyesola Ojewunmi et autres

Kidney disease disproportionately affects populations of African ancestry, yet most genetic studies have focused on Europeans. Here, we present a three-stage genome-wide association study meta-analysis of estimated glomerular filtration rate in ~26,000 individuals across Eastern, Western, and Southern Africa and ~81,000 African-ancestry …

gb, Afrique du Sud, Malawi, Ouganda, us, Mali, de, dk, Nigéria, it (code pays fourni par la source)

KidneyGenAfrica multi-cohort Genome-wide association study and polygenic prediction of kidney function in 110,000 Africans.

Abram Bunya Kamiza, Tinashe Chikowore, Guanjie Chen, Oyesola Ojewunmi et autres

Prevalence and Associated Factors of a Family History of Psychosis: Findings from the Ugandan sample of the NeuroGAP-Psychosis Case-Control Study Family History of Psychosis from NeuroGAP-Uganda

Emmanuel Kiiza Mwesiga, Allan Kalungi, Lerato Majara, Wilber Ssembajjwe et autres

Ouganda, us, gb, Afrique du Sud, Tanzanie, it (code pays fourni par la source)

Linking the plasma proteome to genetics in individuals from continental Africa provides insights into type 2 diabetes pathogenesis

Opeyemi Soremekun, Young-Chan Park, Mauro Tutino, Ana Luiza Arruda et autres

Individuals of African ancestry remain largely underrepresented in genetic and proteomic studies. Here we measure the levels of 2,873 proteins in plasma samples from 163 individuals with type 2 diabetes (T2D) or prediabetes and 362 normoglycemic controls from the Ugandan population. We …

de, Ouganda, Afrique du Sud, gb, us (code pays fourni par la source)

Catatonia Knowledge in Medical Practitioners from Low-Resource Settings Authors

Andrea Kaggwa Kaddu, Daisy Saina Chelagat, Zahra Nasrullah Morawej, Wilber Ssembajjwe et autres

Ouganda, Tanzanie, gb, Afrique du Sud, it (code pays fourni par la source)

KidneyGenAfrica, a pan-African partnership to deliver research and training excellence in genomics of kidney disease

Segun Fatumo, Oyesola Ojewunmi, Rebecca Camenzuli, Christopher Kintu et autres

gb, Ouganda, Afrique du Sud, Nigéria, fr, Malawi, us, it, de (code pays fourni par la source)