Cameron J. Nowell

Cardiomyocyte Analysis - H and E stain with Cellpose

Cameron J. Nowell

Fiji/ImageJ macro code to analyse images, that had been previously marked, of cardiomyocytes in H and E stained mouse heart sections. Developed my Cameron J Nowell of Monash University (cameron.nowell@monash.edu) in collaboration with Miles De Blasio (miles.deblasio@monash.edu)This data set contains the Fiji/ImageJ …

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Cardiomyocyte Analysis - H and E stain with Cellpose

Cameron J. Nowell

Fiji/ImageJ macro code to analyse images, that had been previously marked, of cardiomyocytes in H and E stained mouse heart sections. Developed my Cameron J Nowell of Monash University (cameron.nowell@monash.edu) in collaboration with Miles De Blasio (miles.deblasio@monash.edu)This data set contains the Fiji/ImageJ …

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Unlocking subcellular imaging of a cnidarian photosymbiont Breviolum minutum , through expansion microscopy

Pranali Deore, Cameron J. Nowell, Volker Leen, Douglas R. Brumley et autres

Abstract A cnidarian photosymbiont alga, Breviolum minutum , is an emerging model to study symbiosis due its ability to colonise host in absence of light, and amenability to genetic and physiological manipulations. This alga undergoes subcellular reorganisation in response to stress conditions …

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Dual activation of NLRP3 and pyrin inflammasomes mediates host responses to the human fungal pathogen Coccidioides

Ka Pui Sharon Yau, Jonathan R. Erlich, Priscila Rodríguez, Sara McArdle et autres

Coccidioides is a dimorphic fungal pathogen that grows as a mold in soil and produces infectious arthroconidia. Inhaled arthroconidia transition to spherules containing endospores in mammalian hosts. How distinct developmental forms of Coccidioides interact with immune cells remains poorly defined. Here, we …

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Transmembrane orientation and extracellular juxtamembrane residues of GP130 are critical for signal transduction

Farhad Dehkhoda, Yash Chhabra, Fiona Whelan, Cameron J. Nowell et autres

Glycoprotein 130 (GP130) is an archetypal class I cytokine receptor that serves as a shared signalling subunit for a group of cytokines known as interleukin 6 (IL-6)-type cytokines. GP130 does not have an intrinsic kinase activity and relies on Janus kinases (JAK) …

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Fiji and Friends - AI and ML Using Open Source Software - Manual (v2.0)

Cameron J. Nowell

A training manual covering the use of open source tools for AI and ML processing of images using python environments and the Fiji distribution of ImageJ

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Fiji and Friends - AI and ML Using Open Source Software - Manual (v2.0)

Cameron J. Nowell

A training manual covering the use of open source tools for AI and ML processing of images using python environments and the Fiji distribution of ImageJ

au (code pays fourni par la source)

The Colonic Mucus Layer is Thinner and is Associated with Goblet Cell Hyperplasia in the db/db Mouse Model of Type 2 Diabetes

Matthew C. Rowe, Matthias Demuynck, Abhipree Sharma, Cameron J. Nowell et autres

Abstract Background & Aims Diabetes mellitus has been associated with both intestinal barrier dysfunction and peripheral neuropathy leading to increased risk of infection. The mucus layer forms a physical barrier against pathogens and is a critical component of the intestinal barrier that …

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Sex-Specific Differences in Right Ventricular Function and Remodelling in the Sugen-Hypoxia Mouse Model of Pulmonary Arterial Hypertension

Chloe Landy, Ting Fu, Cameron J. Nowell, Miles J. De Blasio et autres

Salt transformation of TBAJ-876 tartrate to a different stoichiometric form during the preparation of long-acting injectable suspensions for treatment of tuberculosis

Yuen Yi Lam, Malinda Salim, Bryce Barber, Sara J. Fraser‐Miller et autres

TBAJ-876 tartrate undergoes a previously unreported salt transformation during the preparation of long-acting injectable suspensions.

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Two‐Photon Polymerized 3D Geometries to Study Single‐Cell Mechanotransduction and Force Generation in Mesenchymal Stromal Cells

W.R. Perera, Aafreen Ansari, Cameron J. Nowell, Benjamin Geiger et autres

Understanding cellular response to mechanical cues in three-dimensional (3D) environments remains a central challenge in cell biology. Shape and force distribution are key regulators of mechanosensing. In vivo, cells are embedded in 3D environments where force transmission and cytoskeletal behavior differ markedly …

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Contrasting roles for GLP-1R and GIPR in a model of diet-induced obesity

Jie Gao, Shelby Cree, Seungmin Ham, Cameron J. Nowell et autres

The glucagon-like peptide-1 receptor (GLP-1R) and glucose-dependent insulinotropic polypeptide receptor (GIPR) are important incretin receptors that are therapeutic targets for the treatment of type 2 diabetes and obesity. This study extensively characterised the metabolic phenotype of mice with global deletion of either …

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