Giuliana Menegatti

P12.21.B A PHASE 1, FIRST-IN-HUMAN STUDY OF REGORAFENIB PLUS TEMOZOLOMIDE WITH OR WITHOUT RADIOTHERAPY IN PATIENTS WITH NEWLY DIAGNOSED MGMT METHYLATED, IDH WILDTYPE GLIOBLASTOMA: REGOMA-2 TRIAL

Marta Padovan, Matteo Simonelli, Amedeo De Nicolò, Paola Del Bianco et autres

Abstract BACKGROUND Regorafenib (REG) is an oral multikinase inhibitor. In vivo studies demonstrated a synergistic antitumor effect when combined with radiotherapy (RT) and temozolomide (TMZ) against glioblastoma (GBM). We conducted a phase 1 study to evaluate the safety, dose limiting toxicity (DLT), …

it, by (code pays fourni par la source)

660MO A phase I, first-in-human study of regorafenib plus temozolomide with or without radiotherapy in patients with newly diagnosed MGMT methylated, IDH wildtype glioblastoma: The REGOMA-2 trial

M. Padovan, Matteo Simonelli, A. De Nicolò, P. Del Bianco et autres

it, by (code pays fourni par la source)

Response to: Triple occurrence of seizure-associated Takotsubo syndrome

Giacomo Mugnai, Giulia Pasqualin, Alessandra Danese, Daniele Prati et autres

it (code pays fourni par la source)

Tpeak-to-Tend/QT is an independent predictor of early ventricular arrhythmias and arrhythmic death in anterior ST elevation myocardial infarction patients

Giacomo Mugnai, Giovanni Benfari, Alfredo Fede, Andrea da Silveira Rossi et autres

BACKGROUND: The aim of our study was to analyse the markers of transmural dispersion of ventricular repolarization, especially Tpeak-to-Tend and Tpeak-to-Tend /QT ratio, in patients with anterior ST elevation myocardial infarction on admission and to evaluate their association with in-hospital life-threatening arrhythmias …

it (code pays fourni par la source)

Dynamic changes of repolarization abnormalities in takotsubo cardiomyopathy

Giacomo Mugnai, Francesca Vassanelli, Giulia Pasqualin, Giovanni Benfari et autres

OBJECTIVE: This study analyses dynamicchangesin dispersion of ventricularrepolarization over the time course of takotsubo cardiomyopathy (TC), and their relationships with clinical features and life-threatening arrhythmias. METHODS AND RESULTS: All consecutive patients admitted to our division between January 2008 and December 2011 with …

it, us (code pays fourni par la source)

Recurrent multiform Takotsubo cardiomyopathy in a patient with epilepsy: Broken heart or brain?

Giacomo Mugnai, Giulia Pasqualin, Daniele Prati, Giuliana Menegatti et autres

it (code pays fourni par la source)

Acute electrocardiographic differences between Takotsubo cardiomyopathy and anterior ST elevation myocardial infarction

Giacomo Mugnai, Giulia Pasqualin, Giovanni Benfari, Livio Bertagnolli et autres

it (code pays fourni par la source)

Safety and efficacy of the percutaneous radial artery approach for coronary angiography and angioplasty in the elderly.

Gionata Molinari, Ilaria Nicoletti, Marialuisa De Benedictis, Clotilde Terraneo et autres

BACKGROUND: The transradial approach to coronary interventions has been accepted as a safe and effective alternative to the femoral approach due to fewer access site complications and improved patient comfort. In the present study we aimed to investigate the safety and efficacy …

it (code pays fourni par la source)

Quantitative angiographic identification of functional left ventricular aneurysms

Corrado Vassanelli, Giuliana Menegatti, Giorgio Morando, Miriam Turri et autres

Thirty-three 30 degrees RAO left-ventricular angiograms with postinfarction aneurysms were analyzed to determine whether some quantitative variables could describe their morphological characteristics. Seventeen aneurysms were classified as functional (localized without a clear neck), and 16 as true (with a saccular shape). Left-ventricular …

it (code pays fourni par la source)

Endothelial dysfunction late after coronary angioplasty: a quantitative coronary angiographic study in patients without restenosis

Corrado Vassanelli, Miriam Turri, Guido Canali, Giuliana Menegatti et autres

Endothelial function after coronary angioplasty (PTCA) has been evaluated by quantitative coronary angiography in 18 patients with no evidence of significant restenosis at routine angiographic followup. Increasing doses of acetylcholine (Ach) were infused in the dilated coronary artery, followed by a 250 …

it (code pays fourni par la source)

Which Congestive Heart Failure Patient Needs to Be Studied in Haemodynamic Laboratory and When?

Corrado Vassanelli, Giuliana Menegatti

it (code pays fourni par la source)

Successful late coronary angioplasty of infarct-related artery suppresses ST-segment elevation on exercise, without improvement of left ventricular function

Corrado Vassanelli, Giuliana Menegatti, Guido Canali, Gabriele Zanotto et autres

It is not clear whether the ST-segment elevation in the infarct zone during an exercise stress test is caused by expansion of the necrotic area or by ischemia. The purpose of this study was to evaluate the effects of restoring blood flow …

it (code pays fourni par la source)