S. Goffi

Cholinergic Enhancement by Pyridostigmine Potentiates Spontaneous Diurnal but not Nocturnal Growth Hormone Secretion in Short Children

Ezio Ghigo, E. Imperiale, Enrico Mazza, S. Goffi et autres

It has been shown that enhanced cholinergic tone induced by pyridostigmine (PD) increases both basal and GHRH-stimulated GH levels in both adults and children. In this study the effects of PD (60 mg orally) on GH secretion were studied both in the …

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Announcements

Shuso Suemaru, Mary F. Dallman, Daniel N. Darlington, Caren S. Cascio et autres

Effect of 15-day treatment with growth-hormone-releasing hormone alone or combined with different doses of arginine on the reduced somatotrope responsiveness to the neurohormone in normal aging

Ezio Ghigo, Gian Paolo Ceda, Roberto Valcavi, S. Goffi et autres

Ghigo E, Ceda GP, Valcavi R, Goffi S, Zini M, Mucci M, Valenti G, Muller EE, Camanni F. Effect of 15-day treatment with growth hormone-releasing hormone alone or combined with different doses of arginine on the reduced somatotrope responsiveness to the neurohormone …

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Growth hormone-releasing activity of growth hormone-releasing peptide-6 is maintained after short-term oral pretreatment with the hexapeptide in normal aging

Ezio Ghigo, Emanuela Arvat, G Rizzi, S. Goffi et autres

Ghigo E, Arvat E, Rizzi G, Goffi S, Grottoli S, Mucci M, Boghen MF, Camanni F. Growth hormonereleasing activity of growth hormone-releasing peptide-6 is maintained after short-term oral pretreatment with the hexapeptide in normal aging. Eur J Endocrinol 1994;131:499–503. ISSN 0804–4643 The …

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Low doses of either intravenously or orally administered arginine are able to enhance growth hormone response to growth hormone releasing hormone in elderly subjects

Ezio Ghigo, Gian Paolo Ceda, Roberto Valcavi, S. Goffi et autres

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Enhanced adrenocorticotrophic hormone and cortisol responses to corticotrophin-releasing hormone in central idiopathic diabetes insipidus

Enrico Mazza, S. Goffi, Paolo Barchi, Emanuela Arvat et autres

Mazza E, Goffi S, Barchi P, Arvat E, Bellone J, Limone P, Ghigo E, Camanni F. Enhanced adrenocorticotrophic hormone and cortisol responses to corticotrophin-releasing hormone in central idiopathic diabetes insipidus. Eur J Endocrinol 1994;130:121–4. ISSN 0804–4643 It is well known that arginine …

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[Neuroregulation of GH secretion in aging].

Emanuela Arvat, Laura Gianotti, S. Goffi, Mauro Maccario et autres

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Neural Control of Growth Hormone Secretion in Aged Humans

Ezio Ghigo, Emanuela Arvat, S. Goffi, J. Bellone et autres

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A neuroendocrinological approach to evidence an impairment of central cholinergic function in aging

Ezio Ghigo, S. Goffi, Emanuela Arvat, E. Imperiale et autres

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Growth Hormone (GH) Responsiveness to Combined Administration of Arginine and GH-Releasing Hormone Does not Vary with Age in Man*

Ezio Ghigo, S. Goffi, M. Nicolosi, Emanuela Arvat et autres

At present, the mechanism(s) underlying the reduced spontaneous and stimulated GH secretion in aging is still unclear. To obtain new information on this mechanism(s), the GH responses to both single and combined administration of GH-releasing hormone (GHRH; 1 microgram/kg iv) and arginine …

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Pyridostigmine partially restores the GH responsiveness to GHRH in normal aging

Ezio Ghigo, S. Goffi, Emanuela Arvat, M. Nicolosi et autres

In 11 elderly normal subjects and in 17 young healthy subjects we studied the response of plasma growth hormone to GH-releasing hormone (GHRH(29), 1 microgram/kg iv) alone and preceded by pyridostigmine (120 mg orally 60 min before GHRH), a cholinesterase inhibitor likely …

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A new test for the diagnosis of growth hormone deficiency due to primary pituitary impairment: combined administration of pyridostigmine and growth hormone-releasing hormone

Ezio Ghigo, E. Imperiale, G. M. Boffano, Enrico Mazza et autres

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