2026
conference-abstract
OpenAlex
Cengiz Goekeri, Sebastian M.K. Schickinger, Alina Nettesheim, Kerstin Linke et autres
Background: About 23% of healthy Europeans carry Fucosyltransferase (FUT)2 mutations, lacking terminally fucosylated glycans in mucosal secretions, which alters susceptibility to various infections. Aims: To elucidate how Streptococcus pneumoniae (S.pn.) modulates and exploits glycosylated host factors during infection in experimental models and …
de, us
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2024
conference-abstract
OpenAlex
Cengiz Goekeri, Sebastian M.K. Schickinger, Alina Nettesheim, K. Linke et autres
Background: Mucosal surfaces are rich in N- and O-glycans containing terminal sugars such as fucose. A frequency of individuals have a mutation in the FUT2 gene, resulting in the inability to secrete α-(1,2)-fucosylated glycans. Such mutations render these individuals susceptible or resistant …
de, us
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Jade Bath, Elisabet Bjånes, Cengiz Goekeri, Jeff C. Hsiao et autres
us, de
(code pays fourni par la source)
Accès ouvert
2022
article
OpenAlex
Lindsey R. Burcham, Jade Bath, Caroline A. Werlang, Laurie M. Lyon et autres
Mucin glycoproteins are a major component that contributes to the complexity of the female reproductive tract (FRT). Group B Streptococcus (GBS) is present in the FRT of 25–30% of healthy women, but during pregnancy can ascend to the uterus to cause preterm …
us
(code pays fourni par la source)
Accès ouvert
2021
article
OpenAlex
Abigail McShane, Jade Bath, Ana Maria Jaramillo, Caroline E. Ridley et autres
us, gb
(code pays fourni par la source)
Accès ouvert
2019
conference-abstract
OpenAlex
Robert L. Summers, Manu Vanaerschot, James M. Murithi, Charisse F. Pasaje et autres
Indonesia carries the heaviest burden of soil-transmitted helminth (STH) infection in Southeast Asia with more than 62 million children requiring preventative chemotherapy in 2017 alone. Prevalence data for many parts of the country are out-dated and knowledge of the risk factors involved …