Claudio Franzutti

Usefulness of Bedside Point-of-care Ultrasounds in Intensive Care Unit for Septic Patients: A Consensus Statement of the Italian Society of Echocardiography and Cardiovascular Imaging

Marco Tescione, Andrea Piccolo, Eugenio Giuseppe Vadalà, Claudio Franzutti et autres

Sepsis and septic shock remain major causes of morbidity and mortality and are frequently complicated by multiple organ dysfunction, making management particularly challenging for intensivists. Early recognition of hemodynamic instability, prompt identification of the infectious source, and timely interventions are crucial to …

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How to Do Echo in Septic Cardiomyopathy: A Consensus Statement of the Italian Society of Echocardiography and Cardiovascular Imaging

Marco Tescione, Andrea Piccolo, Eugenio Giuseppe Vadalà, Antonio Giuseppe Posteraro et autres

Septic cardiomyopathy (SCM) is an acute, reversible myocardial dysfunction occurring in the context of sepsis, independent of ischemic heart disease. Despite its frequent occurrence in critically ill patients, SCM remains poorly defined and underdiagnosed. This article provides clinicians with a practical guide …

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The role of PMCT in firearm injuries. Case study.

Concetta Pitrone, Susan Pellicano, Claudio Franzutti, Giuseppe Scappatura et autres

Background: The use of radiological approaches in forensic investigations is rapidly emerging as an alternative to traditional autopsies. Here, we present the experience of the Sicilian and Calabrian forensic medical departments over the past five years, highlighting the application of PMCT to …

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Congenital Ventricular Diverticulum

Carmelo Massimiliano Rao, Fabiana Lucà, Claudio Franzutti, Giuseppe Scappatura et autres

Herein, we describe a 54-year-old patient with a congenital ventricular diverticulum (CVD), referred to our emergency department for presyncope episodes and multiple re-entrant ventricular tachycardias (VT). Significantly, echocardiographic findings were not clear, and the diagnosis was made by cardiac magnetic resonance imaging …

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Late-onset fabry disease due to the p.Phe113Leu variant: the first italian cluster of five families

Vittoria Cianci, Angelo Pascarella, Lucia Manzo, Sara Gasparini et autres

BACKGROUND: The GLA c.337T > C (p.Phe113Leu) is a known pathogenic variant associated to late-onset Fabry disease phenotype with predominant cardiac manifestations. A founder effect was demonstrated in a large cohort in the Portuguese region of Guimarães. Herein we report an in-depth …

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Late-onset Fabry disease due to a new (p.Pro380Leu) pathogenic variant of GLA Gene

Vittoria Cianci, Angelo Pascarella, Sara Gasparini, Vincenzo Angelo Donadio et autres

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Retroperitoneal ganglioneuroma in a 15-year-old boy, an interesting case studied through multimodal imaging

Carmela Falcone, G Calafiore, Lucia Paola Vazzana, Lara Natoli et autres

Benign ganglioneuroma contains mature autonomous ganglion cells, including satellite cells and long axonal processes, as well as Schwann cells, which come from neural crest-derived cells that form the adrenal medulla and sympathetic nervous system during embryonic development and is a rare benign …

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527 An incidental diagnosis in a patient with SARS-CoV-2 pneumonia

Annita Bava, Concetta Nadia Aricò, Rocco Caridi, Filippo Rodà et autres

Abstract Hypertrophic cardiomyopathy (HCM) is the most frequent genetic disease of the myocardium, with a prevalence of 1:500 cases in the general population. The salient feature is a hypertrophy, symmetrical or not, of the walls of the left ventricle (mainly the septum, …

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816 UNA Diagnosi . . . Incidentale

Annita Bava, Concetta Nadia Aricò, Rocco Caridi, Filippo Rodà et autres

Abstract Hypertrophic cardiomyopathy (HCM) is the most frequent genetic disease of the myocardium, with a prevalence of 1:500 cases in the general population. The salient feature is a hypertrophy, symmetrical or not, of the walls of the left ventricle (mainly the septum, …

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Identifying and managing CAR T-cell–mediated toxicities: on behalf of an Italian CAR-T multidisciplinary team

Massimo Vincenzo Martino, Sebastiano Macheda, Umberto Aguglia, Luciano Arcudi et autres

INTRODUCTION: Chimeric antigen receptor (CAR)-T-cell therapy is a new treatment for patients with hematologic malignancies in which other therapies have failed. AREAS COVERED: The review provides an overview for recognizing and managing the most acute toxicities related to CAR-T cells. EXPERT OPINION: …

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