Allen Mo

Reirradiation of lower gastrointestinal Cancer: A survey of ongoing trials by the Reirradiation Collaborative group (ReCOG)

Camilla Kronborg, Ane Appelt, Pim Burger, Kyle Cuneo et autres

Phase 1 Study of Online Proton Adaptive RadioTherapY (PARTY)

Weiren Liu, Hailei Zhang, Thomas Mazur, Joshua P. Schiff et autres

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A Gaussian-Based Planning Approach for Robust Dose-Escalated Stereotactic Body Proton Therapy

Xiandong Zhao, Thomas R. Mazur, H Steven Zhang, S Wang et autres

PURPOSE: Proton plans are often very homogeneous with minimal hotspots compared with the prescribed dose, which may not be ideal for ablative stereotactic body radiation therapy (SBRT). A treatment planning approach for stereotactic body proton therapy (SBPT) is proposed to match the …

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Development and in silico validation of an online adaptive workflow for proton therapy with an in-room synchrocyclotron and CT-on-rails

Hailei Zhang, Weiren Liu, Allen Mo, Thomas R. Mazur et autres

PURPOSE: Development and validation of an online adaptive proton therapy workflow for clinical use. METHODS: A script-based online adaptive proton therapy workflow was developed in a graphics processing unit (GPU)-accelerated treatment planning system (TPS) to automate plan adaptation using traditional CT images …

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Technical note: clinical real-time multi-target, 3D-motion tracking radiation delivery on a magnetic resonance linear accelerator

Taeho Kim, Justin Ross, Emily McHugh, Marissa Maxwell et autres

Abstract Background. The purpose of this study was to demonstrate the feasibility of multi-target 3D-motion tracking for use in magnetic resonance-imaging (MRI)-guided, stereotactic body radiotherapy for upper abdominal targets. This paper focuses on the clinical testing of a real-time 3D-motion tracking process …

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Adaptive Salvage Stereotactic Radiation for Locoregional Recurrence of Pancreatic Adenocarcinoma After Surgery

David S. Lakomy, Michael Padgett, Kylie H. Kang, Richard Tsai et autres

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Neoadjuvant epacadostat (INCB024360) combined with short course radiotherapy in patients with locally advanced rectal cancer: Efficacy and safety from a phase 2 trial.

M. Khushman, Haeseong Park, Katrina S. Pedersen, Amberly Brown et autres

162 Background: In preclinical studies, the tryptophan-metabolizing enzyme, Indoleamine 2, 3-dioxygenase 1 (IDO1), promotes resistance to radiation in colorectal cancer, and IDO1 inhibition with epacadostat improves tumor radiosensitivity. In a phase 1 trial, patients (pts) with locally advanced rectal cancer (LARC, n=17) …

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A phase II study of stereotactic body radiotherapy and focal adhesion kinase inhibitor in advanced pancreatic adenocarcinoma.

Hyun Kim, Kian-Huat Lim, Bita Kalaghchi, Allen Mo et autres

740 Background: There are limited treatment options for pts with borderline resectable (BRPC) and locally advanced (LAPC) pancreatic ductal adenocarcinoma (PDAC). Stereotactic body radiation therapy (SBRT) permits ablative radiation dosing in fewer treatments, which may spare radiation depletion of immune cells. Focal …

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RNF216P1 functions as an oncogenic gene through modulating miR-195-5p/ATG4B axis in hepatocellular carcinoma

Kai Li, Yaping Bai, Jingtong Wang, Ren Li et autres

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Evaluating Short Course Radiation and ctDNA for Organ Preservation: The Nonoperative Management and Early Response Assessment in Rectal Cancer (NOM-ERA) Trial

Hyun Kim, C.J. Anker, Jeffrey R. Olsen, C.L. Hallemeier et autres

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Salvage Adaptive Radiation Therapy for Locoregional Recurrence of Pancreatic Adenocarcinoma

Miles J. Padgett, David S. Lakomy, K.H. Kang, Richard Tzong‐Han Tsai et autres

Purpose/Objective(s) Isolated locoregional recurrence of pancreatic adenocarcinoma (PDAC) occurs after surgical resection in 25-50% of cases and has limited treatment options. There is a paucity of data for using daily online adaptive radiation therapy (ART) for isolated locoregional recurrence after definitive local …

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IMPARC: A Prospective Trial of Stereotactic Proton Reirradiation for Locoregionally Recurrent Rectal Cancer

P. Dalwadi, Allen Mo, R Chin, C. Hatscher et autres

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