Myung Hwan Park

Donor‐Engineered Chiral Indium–Salen Complexes for Tunable Circularly Polarized Luminescence

Haein Kim, Minseo Ji, Khuslen Bazarragchaa, Yubin Choi et autres

ABSTRACT High‐performance circularly polarized luminescent (CPL) materials with efficient emission and tunable chiroptical responses are highly desirable for emerging photonic and optoelectronic technologies, yet design principles for main‐group CPL emitters remain underdeveloped. Here, we establish a donor‐engineering strategy for chiral indium–salen complexes …

kr (code pays fourni par la source)

Highly blue‐emissive CBZ ‐functionalized salen– In complexes: Influence of structural rigidity and donor substituent quantity

Yoseph Kim, Jaehoon Kim, Ji Hye Lee, Hyeongkwon Moon et autres

Abstract Indium–salen complexes with electron‐donating carbazole (CBZ) groups at positions 4 (CBZIn1) and both 4 and 6 (CBZIn2) were synthesized and characterized to explore the impact of the number of substituents and the structural rigidity on their photophysical properties. The single‐crystal structure …

kr (code pays fourni par la source)

Desymmetrization on electron-withdrawing groups in single benzene fluorophores for fine tuning of photophysical properties and applications

Jun Yeong Kim, Hae-In Kim, Dopil Kim, Chae Young Ryu et autres

alternative synthetic routes. Various electron-donating groups (EDGs) and electron-withdrawing groups (EWGs) were introduced at one ester group position, yielding 12 A series compounds with emission wavelengths spanning from 440 to 578 nm. EDGs led to blue-shifts, while EWGs induced red-shifts relative to …

kr (code pays fourni par la source)

Photophysical properties of 9,9‐dimethyl‐9,10‐dihydroacridine‐functionalized salen–indium complexes: Effects of structural rigidity and number of donor substituents

Yoseph Kim, Ji Hye Lee, Jaehoon Kim, Hyeonkwon Moon et autres

Abstract Indium–salen complexes with electron‐donating 9,9‐dimethyl‐9,10‐dihydroacridine (DMAC) groups at positions 4 (DMACIn1) and 4 and 6 (DMACIn2) were synthesized and characterized to investigate the effect of the substituents number and structural rigidity on photophysical properties. The single crystal structure of DMACIn1 revealed …

kr (code pays fourni par la source)

Cu‐Catalyzed Oxidative Tandem Coupling and Cyclization of 2‐Aminonaphthalenes to Synthesize Dibenzo[c, g]carbazoles

Arnab Ghosh, Myung Hwan Park, Min Kim, Houng Kang

Abstract A Cu(II) complex with a bipyridyl ligand bearing a Brønsted acid was used to catalyze the tandem oxidative coupling and cyclization of 2‐aminonaphthalenes to give N‐substituted‐dibenzo[c,g]carbazoles. The incorporation of an appended acidic moiety to the ligand was found to be key …

kr (code pays fourni par la source)

Synthesis and Derivatization of Diaminobenzene Fluorophores with Amine Protecting Groups

Dokyoung Kim, Myung Hwan Park, Min Kim, Hae-In Kim et autres

Abstract Introducing two electron-donating groups and two electron-withdrawing groups together in symmetrical positions on the benzene ring is a fundamental way to synthesize and prepare single-benzene-based fluorophores (SBBFs). Their photophysical properties are adjusted through the electronic and structural properties of the functional …

kr (code pays fourni par la source)

Efficacy and safety of BVAC-C in HPV type 16- or 18–positive cervical carcinoma who failed 1st platinum-based chemotherapy: a phase I/IIa study

Chel Hun Choi, Jeong‐Won Lee, Duk‐Soo Bae, Eun‐Suk Kang et autres

Background: BVAC-C, a B cell- and monocyte-based immunotherapeutic vaccine transfected with recombinant HPV E6/E7, was well tolerated in HPV-positive recurrent cervical carcinoma patients in a phase I study. This phase IIa study investigates the antitumor activity of BVAC-C in patients with HPV …

kr (code pays fourni par la source)

Positional effects of electron-donating and withdrawing groups on the photophysical properties of single benzene fluorophores

Dopil Kim, Jun Yeong Kim, Hae-In Kim, Minhyuk Lee et autres

We investigated how the positional arrangement of electron-donating (amino) and electron-withdrawing (ester) groups in single benzene-based fluorophores influences their emission properties. By synthesizing 26 regioisomeric fluorophores, we achieved wavelength modulation from 322 to 539 nm, revealing key correlations between functional group positioning …

kr (code pays fourni par la source)

CCDC 2181549: Experimental Crystal Structure Determination

Hanif Mubarok, Sang Woo Kwak, Ji Hye Lee, Hyonseok Hwang et autres

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, …

CCDC 2217389: Experimental Crystal Structure Determination

Yoseph Kim, Jaehoon Kim, Ji Hye Lee, Hyeongkwon Moon et autres

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, …

First-in-Human Phase 1 Study of a B Cell– and Monocyte-Based Immunotherapeutic Vaccine against HER2-Positive Advanced Gastric Cancer

Minkyu Jung, Jii Bum Lee, Hyo Song Kim, Woo Sun Kwon et autres

PURPOSE: BVAC-B is an autologous B cell- and monocyte-based immunotherapeutic vaccine that contains cells transfected with a recombinant human epidermal growth factor receptor 2 (HER2) gene and loaded with the natural killer T cell ligand alpha-galactosylceramide. Here, we report the first BVAC-B …

kr (code pays fourni par la source)

Design and Dynamics Analysis of the Weft Feed Module of Carbon Fiber Spread Tow Weaving Loom

Ki-Seok Byeon, Soon-Ok Jo, Myung Hwan Park