Juan Daniel Castillo Gómez

Hyperthermia-induced doxorubicin delivery from thermosensitive liposomes via MR-HIFU in a pig model

Lukas Christian Sebeke, Juan Daniel Castillo Gómez, Edwin Heijman, Pia Rademann et autres

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Visualization of thermal washout due to spatiotemporally heterogenous perfusion in the application of a model-based control algorithm for MR-HIFU mediated hyperthermia

Lukas Christian Sebeke, Pia Rademann, Alexandra Claudia Maul, Sin Yuin Yeo et autres

Purpose This article will report results from the in-vivo application of a previously published model-predictive control algorithm for MR-HIFU hyperthermia. The purpose of the investigation was to test the controller’s in-vivo performance and behavior in the presence of heterogeneous perfusion.Materials and methods …

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Dataset CMKLR1-targeting peptide tracers for PET/MR imaging of breast cancer

Sarah Erdmann, Lars Niederstadt, Eva J. Koziolek, Juan Daniel Castillo Gómez et autres

Dataset for the menuscript CMKLR1-targeting peptide tracers for PET/MR imaging of breast cancer

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Dataset CMKLR1-targeting peptide tracers for PET/MR imaging of breast cancer

Sarah Erdmann, Lars Niederstadt, Eva J. Koziolek, Juan Daniel Castillo Gómez et autres

Dataset for the menuscript CMKLR1-targeting peptide tracers for PET/MR imaging of breast cancer

de (code pays fourni par la source)

CMKLR1-targeting peptide tracers for PET/MR imaging of breast cancer

Sarah Erdmann, Lars Niederstadt, Eva J. Koziolek, Juan Daniel Castillo Gómez et autres

Abstract Molecular targeting remains to be a promising approach in cancer medicine. Knowledge about molecular properties such as overexpression of G protein-coupled receptors (GPCRs) is thereby offering a powerful tool for tumor-selective imaging and treatment of cancer cells. We utilized chemerin-based peptides …

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Dataset CMKLR1-targeting peptide tracers for PET/MR imaging of breast cancer

Sarah Erdmann, Lars Niederstadt, Eva J. Koziolek, Juan Daniel Castillo Gómez et autres

Dataset for the menuscript CMKLR1-targeting peptide tracers for PET/MR imaging of breast cancer

de (code pays fourni par la source)

CMKLR1-targeting peptide tracers for PET/MR imaging of breast cancer

Sarah Erdmann, Lars Niederstadt, Eva J. Koziolek, Juan Daniel Castillo Gómez et autres

Background: Molecular targeting remains to be a promising approach in oncology.Overexpression of G protein-coupled receptors (GPCRs) in human cancer is offering a powerful opportunity for tumor-selective imaging and treatment employing nuclear medicine.We utilized novel chemerin-based peptide conjugates for chemokine-like receptor 1 (CMKLR1) …

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Thiourea derivatives as chelating agents for bioconjugation of rhenium and technetium

Juan Daniel Castillo Gómez, Adelheid Hagenbach, Ulla I. M. Gerling‐Driessen, Beate Koksch et autres

Tc(HL)] product as well as for its bioconjugate and recommend this class of compounds for further bioconjugation studies towards clinical applications.

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CCDC 1547255: Experimental Crystal Structure Determination

Juan Daniel Castillo Gómez, A. Hagenbach, Ulla I. M. Gerling‐Driessen, Beate Koksch et autres

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, …

CCDC 1547253: Experimental Crystal Structure Determination

Juan Daniel Castillo Gómez, A. Hagenbach, Ulla I. M. Gerling‐Driessen, Beate Koksch et autres

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, …

CCDC 1547254: Experimental Crystal Structure Determination

Juan Daniel Castillo Gómez, A. Hagenbach, Ulla I. M. Gerling‐Driessen, Beate Koksch et autres

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, …

Propargyl‐Substituted Thiocarbamoylbenzamidines of Technetium and Rhenium: Steps towards Bioconjugation with Use of Click Chemistry

Juan Daniel Castillo Gómez, Adelheid Hagenbach, Ulrich Abram

A new propargyl‐substituted thiocarbamoylbenzamidine has been synthesized. The compound acts as a tetradentate ligand and forms stable complexes with {ReVO}3+ and {TcVO}3+ cores. Click couplings of the resulting complexes with benzylazide lead to prototype triazole derivatives, which were analyzed by NMR and …

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