Ayça Tan

Clinicopathologic Significance of Tumor Deposits in Colon Adenocarcinoma: Associations with Regional Tumor Burden and Adverse Invasive Features

Ömer Atmış, Sema Ocak, Hanife Seda Mavili, Fatma Seher Pehlivan et autres

Objective: To evaluate whether tumor deposit presence was associated with histologically confirmed regional lymph node metastasis in colon adenocarcinoma. Associations with other clinicopathologic features, tumor deposit count, and overall survival were evaluated as secondary or exploratory objectives.Material and Methods: This retrospective cohort …

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Histopathologic clues to mismatch repair deficiency in colon adenocarcinoma: the role of mucinous component and intratumoral/Crohn-like immune response

Ömer Atmış, Sema Ocak, Fatma Seher Pehlivan, Hanife Seda Mavili et autres

BACKGROUND: Deficient mismatch repair (dMMR) identifies a biologically distinct subset of colon adenocarcinomas with important diagnostic, hereditary, prognostic, and therapeutic implications. This study investigated whether mucinous component and immune response pattern may serve as practical histopathologic clues to dMMR in routine pathology …

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Association Between SUVmax and Tumour-Stroma Ratio in Breast Cancer: A Pathological Correlation Study

Fatma Esra Ateş Kahya, Mehmet Onur Kahya, Feray Aras, Devrim Önder et autres

Objective: In our study, we purposed to investigate the correlation between tumour-stroma ratio, which is considered a prognostic marker in many types of cancer, and lesion maximum standardized uptake values (SUVmax), which is a semiquantitative parameter, and to show that, if significant, …

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Incidental serrated lesions of the appendix: analysis of 2,137 appendectomy specimens

Ömer Atmış, Ecem Dokuzlu Küçük, Hanife Seda Mavili, Fatma Seher Pehlivan et autres

BACKGROUND: Serrated lesions of the appendix are rare, often incidental findings in routine appendectomy specimens. Their true frequency, histopathologic spectrum, and anatomic distribution remain incompletely characterized, partly due to variability in sampling practices. METHODS: We retrospectively reviewed 2,137 appendectomy specimens (2015-2025) from …

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Malignant Adenomyoepithelioma of the Breast with Soft Tissue Metastasis and an Aggressive Course: A Rare Case Report

Hanife Seda Mavili, Ömer Atmış, Fatma Seher Pehlivan, Atike Pınar ERDOĞAN et autres

Malignant adenomyoepithelioma (M-AME) of the breast is an extremely rare neoplasm. It demonstrates a wide range of morphological features and clinical behaviors, including the potential for distant metastasis. We present a 41-year-old female patient who was initially diagnosed with an intraductal papilloma …

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LB1066 Medicare trends in auricular cartilage and composite graft utilization amongst Mohs surgeons and other specialists from 2013 to 2022

Samantha S. Sattler, Ayça Tan, Jordan B. Slutsky

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Case Report: Mitral Valve Chordae Tendineae Rupture and Splenic Infarction in Granulomatosis With Polyangiitis

İrem ŞAHİNOĞLU, Sadettin Uslu, Fatma Can, Mustafa Uçar et autres

The data that support the findings of this study are available from the corresponding author upon reasonable request.

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Clinicopathological Reflections of Hashimoto’s Thyroiditis and Papillary Thyroid Carcinoma Coexistence

Can Akçura, Samet Alkan, Sedat Can Güney, Gamze Gelir Cavdar et autres

Are Inflammation Markers Derived from Hemogram Parameters Predictive for Papillary Thyroid Carcinoma in Hashimoto’s Thyroiditis Patients?

Can Akçura, Sedat Can Güney, Samet Alkan, Gamze Gelir Cavdar et autres

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653P A phase I dose escalation study of EBC-129, a first-in class, anti N-glycosylated CEACAM5 & CEACAM6 antibody-drug conjugate (ADC) in patients with solid tumors

Matthew Chau Hsien Ng, Wei Peng Yong, F. Meric-Bernstam, Robert William Lentz et autres

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Tumor Budding Should Be in Oral Cavity Cancer Reporting: A Retrospective Cohort Study Based on Tumor Microenvironment

Ayça Tan, Toros Taşkın

The utility of histological grading, which is useful in predicting prognosis in many tumors, is controversial for oral squamous cell carcinoma (OSCC). Therefore, new histopathological parameters should be added to histopathology reports of OSCCs. The study aimed to evaluate the parameters of …

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p53 and PTEN expression evaluation with molecular evident recent criteria in laryngeal carcinoma

Ayça Tan, Görkem Eskiizmir, Uğur Kamiloğlu, Sülen Sarıoğlu

The prognosis of laryngeal cancer is affected by clinicopathological factors. Because of that, an effective prognostic marker is very valuable in managing the clinical process. The p53 evaluation method, used in the literature recently, was used for the first time in laryngeal …

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