Accès ouvert
2026
review
OpenAlex
Dimitrios Rallis, Virna-Maria Tsitou, Ivan Gerdzhikov, Raya G. Grozdanova-Uzunova et autres
Implant-supported provisional restorations preserve function, esthetics, occlusal stability, and peri-implant soft tissue architecture before definitive rehabilitation. These restorations are commonly fabricated from PMMA/PEMA resins, bisacryl composites, CAD/CAM-milled polymers, and additively manufactured resins, all of which may release residual methacrylate monomers into the …
bg
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Accès ouvert
2026
article
OpenAlex
Snezhana Rusinova‐Videva, Maya M. Zaharieva, Dimitrina Zheleva‐Dimitrova, Vesela Lozanova et autres
The extreme Antarctic environment offers unique living conditions. The organisms inhabiting Antarctica have a specific metabolism through which they overcome the challenges of large temperature amplitudes, long periods of light or darkness, and intense UV radiation. Microorganisms are ubiquitous in Antarctica and …
bg
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Accès ouvert
2026
article
OpenAlex
Meglena I. Kandinska, Peter G. Boyadzhiev, Trayana S. Nedeva, Stanimira T. Ivanova et autres
Foodborne diseases remain a major global public health concern. According to the World Health Organization (WHO), contaminated food causes nearly 500,000 deaths annually. Consequently, the development of novel strategies to control foodborne pathogens and prevent microorganism-induced plant diseases remains an important research …
bg, ee
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Accès ouvert
2026
article
OpenAlex
Rositsa Mihaylova, Nikolay Bebrivenski, Dimitrina Zheleva-Dimitrova, Rumyana Simeonova et autres
extract (ESE) and its ability to synergistically enhance cisplatin cytotoxicity in HT-29 colorectal carcinoma cells. Cell viability was assessed using the MTT assay, followed by formal combination analysis based on the Chou-Talalay methodology. Combination experiments employed a non-constant ratio regimen in which …
bg
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Accès ouvert
2025
article
OpenAlex
Inna Sulikovska, Tanya Toshkova-Yotova, Elina Tsvetanova, Vera Djeliova et autres
The rising incidence of cancer and the limitations of current therapeutic strategies underscore the urgent need to identify novel bioactive compounds for antitumor drug development. Cyanobacteria are widespread Gram-negative, photoautotrophic prokaryotes that have been recognized as an important source of biologically active …
bg
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Accès ouvert
2025
article
OpenAlex
Niya Emilova Semerdzhieva, Simeon Dimitrov, Adelina Tsakova, Мариана Господинова et autres
(1) Introduction: Distal coronary emboli occur in up to 15–30.5% of patients undergoing percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI) and are associated with poor myocardial reperfusion in the territory of the infarct-related artery. The objective of this study was …
bg, us
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Accès ouvert
2025
article
OpenAlex
Rumyana Dimova, Vesela Lozanova, Nevena Chakarova, Mina Serdarova et autres
BACKGROUND: The aim of this study was to determine the ceramide subspecies profile in people with impaired 1-hour or 2-hour postload glucose during a 75 g oral glucose tolerance test (OGTT) and their association with cardiometabolic parameters. METHODS: ) who underwent a …
bg, it
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Accès ouvert
2025
article
OpenAlex
Niya Emilova Semerdzhieva, Adelina Tsakova, Vesela Lozanova
Background: Estrogens play a protective role during the early stages of life. However, endogenous 17β-estradiol (E2) can accelerate atherosclerosis progression. Aim: The purpose of this study was to test for the significance of the sex-specific associations of gonadal hormones with the extent …
bg
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Accès ouvert
2025
article
OpenAlex
Krasimira Tasheva, Inna Sulikovska, Ani Georgieva, Vera Djeliova et autres
Salvia aethiopis L. (Mediterranean sage) is a medicinal plant known for its rich phenolic content and different therapeutic properties. This study evaluated the phytochemical composition, antioxidant capacity and anticancer potential of water extracts from in vitro cultivated S. aethiopis. The extract exhibited …
bg
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Accès ouvert
2025
article
OpenAlex
Kristina B. Simeonova, Ana I. Koleva, Nevena I. Petkova‐Yankova, Anna-Mariya R. Zlatanova et autres
The current study is a continuation of our previous investigations into the radical homodimeric reaction mechanism of 3-acetylcoumarin. In the current study, the effects of different substituents on the coumarin ring of 3-acetylcoumarin are investigated both experimentally and theoretically. Several 3-acetylcoumarin derivatives …
bg
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Accès ouvert
2024
article
OpenAlex
Nikolay Ishkitiev, Maria Micheva, Marina Miteva, Stefaniya Gaydarova et autres
The development of fluorescence-based methods for bioassays and medical diagnostics requires the design and synthesis of specific markers to target biological microobjects. However, biomolecular recognition in real cellular systems is not always as selective as desired. A new concept for creating fluorescent …
bg, de, es
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Accès ouvert
2024
article
OpenAlex
Maria Ivanova, Joana Zaharieva, Martin Tsvetkov, Vesela Lozanova et autres
For very first time, we report the synthesis of 8-(2-methoxyphenyl)-6-methyl-2-(1-methyl-1H-benzo[d]imidazol-2-yl)quinoline 1. This was achieved in several steps, including usage of the Suzuki reaction for functionalization of 2-(1H-benzo[d]imidazol-2-yl)quinoline moiety. The new compound exhibits blue fluorescence. Its structure was confirmed with 1D and 2D …
bg, de
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