Sheldon A. Magder

Hidden effects of dobutamine on cardiac output

Christopher Lai, Talal Shaikhain, Sheldon A. Magder

BACKGROUND: Dobutamine exerts its pharmacological effects by stimulating α1-, β1-, and β2-adrenergic receptors. Activation of these receptors increase both the force of cardiac contraction (inotropy) and heart rate (chronotropy). Despite its well-established cardiac effects, the influence of dobutamine on vascular tone remains …

fr, ca (code pays fourni par la source)

The Etiology and Management of Critical Acute Right Heart Failure

Adriana C. Luk, Ricardo Teijeiro‐Paradis, Andrew Kochan, Filio Billia et autres

Right ventricular failure contributes to the morbidity and mortality of acute myocardial function, massive pulmonary embolism, and chronic pulmonary hypertension. Understanding how the normal physiology of the right ventricle (RV) is disrupted is integral to managing patients who present with RV decompensation. …

ca (code pays fourni par la source)

Physiological complexities of intraabdominal hypertension: taming the elephant

Sheldon A. Magder

ca (code pays fourni par la source)

Physiological and clinical significance of mean circulatory and mean systemic filling pressure

Sheldon A. Magder, Douglas Slobod, Antoine Vieillard‐Baron

A pressure distends blood vessels even when the heart is not beating and there is no blood flow. This is called mean circulatory filling pressure (MCFP). We will first discuss why it is physiologically necessary to have this base pressure. Although all …

ca (code pays fourni par la source)

Misunderstanding buffering in critical illness

Sheldon A. Magder

ca (code pays fourni par la source)

Association between arterial oxygen and mortality across critically ill patients with hematologic malignancies: results from an international collaborative network

Guillaume Dumas, Idunn S. Morris, Tamishta Hensman, Sean M. Bagshaw et autres

ca, fr, au, gb (code pays fourni par la source)

Long-term survival and functional outcomes of critically ill patients with hematologic malignancies: a Canadian multicenter prospective study

Laveena Munshi, Guillaume Dumas, Bram N. Rochwerg, Farah Shoukat et autres

ca, fr (code pays fourni par la source)

Reduction in Postoperative Right Ventricular Echocardiographic Indices Predicts Longer Duration of Vasoactive Support After Cardiac Surgery

Nawaporn Assanangkornchai, Valérie Villeneuve, Sarah McDonald, Dominique Shum Tim et autres

ca, th (code pays fourni par la source)

The use of Guyton’s approach to the control of cardiac output for clinical fluid management

Sheldon A. Magder

Infusion of fluids is one of the most common medical acts when resuscitating critically ill patients. However, fluids most often are given without consideration of how fluid infusion can actually improve tissue perfusion. Arthur Guyton's analysis of the circulation was based on …

ca (code pays fourni par la source)

Right atrial pressure and Guyton’s approach to fluid management

Sheldon A. Magder

ca (code pays fourni par la source)

The Ins and Outs of IV Fluids in Hemodynamic Resuscitation

DAVID A.S. KAUFMAN, Marcela Lopes, Niharika Maviya, Sheldon A. Magder

OBJECTIVES: Concise definitive review of the physiology of IV fluid (IVF) use in critically ill patients. DATA SOURCES: Available literature on PubMed and MEDLINE databases. STUDY SELECTION: Basic physiology studies, observational studies, clinical trials, and reviews addressing the physiology of IVF and …

us, ca (code pays fourni par la source)

Severe Tricuspid Regurgitation and the Potential for a Spiral of Death

Sheldon A. Magder, Nicolò Piazza

ca (code pays fourni par la source)