Runda Wu

Environmental eustress inhibits CCL2 to overcome doxorubicin-induced cardiotoxicity and alleviate tumor growth

Peiyuan Bai, Chaobao Liu, Ao Liu, Zehao Zhuang et autres

cn (code pays fourni par la source)

Association of serum uric acid levels and atrial fibrillation risk in middle-aged and older adults from the UK Biobank cohort

Runda Wu, Yuwei Peng, Jia Huang, Yuxiang Dai

ObjectiveTo explore the association between serum uric acid levels and the cumulative incidence risk of atrial fibrillation, and to evaluate the predictive value of different uric acid levels for the onset of atrial fibrillation. MethodsA retrospective selection of 451 879 participants from …

Queuine tRNA ribosyltransferase 1 deficiency ameliorates hepatic steatosis and atherosclerosis possibly via modulating lipogenesis

Runda Wu, Shuning Zhang, Wanxin Wang, Zheng Dong et autres

cn (code pays fourni par la source)

Cross-sectional comparative evaluation of US and China-developed large language models for bilingual coronary heart disease patient education

Kaiyuan Liu, Wanxin Wang, Runda Wu, Chenguang Li et autres

: Patient education for coronary heart disease (CHD) is increasingly facilitated by large language models (LLMs). However, it remains unclear whether the origin of the models (United States vs. China) affects their performance in providing CHD-related patient education. This study aimed to …

cn (code pays fourni par la source)

Prognostic Value of Functional Incomplete Revascularization in Patients Undergoing Valve Surgery With Coronary Artery Disease

Fang Zhang, Wei Gao, Wenshuo Wang, Runda Wu et autres

BACKGROUND: Coronary angiography remains standard for assessing lesions in valve surgery patients with concomitant coronary artery disease. OBJECTIVES: This study assessed the prognostic value of functional evaluation using quantitative flow ratio in these patients. METHODS: Consecutive patients undergoing valve surgery (January 2016-December …

cn (code pays fourni par la source)

Colorectal carcinoma organoid and cancer-associated fibroblasts co-culture system for drug evaluation

Yan Wang, Zilin Zhang, Xiaoran Li, Xiao‐Bing Lu et autres

cn, kr (code pays fourni par la source)

Metabonomic Biomarkers of Plaque Burden and Instability in Patients With Coronary Atherosclerotic Disease After Moderate Lipid‐Lowering Therapy

Zhendong Mei, Lili Xu, Qingxia Huang, Chenhao Lin et autres

BACKGROUND: Contemporary risk assessment in patients with coronary atherosclerotic disease (CAD) often relies on invasive angiography. However, we aimed to explore the potential of metabolomic biomarkers in reflecting residual risk in patients with CAD after moderate lipid-lowering therapy. METHODS AND RESULTS: We …

cn (code pays fourni par la source)

Exome Sequencing Identified Susceptible Genes for High Residual Risks in Early‐Onset Coronary Atherosclerotic Disease

Runda Wu, Ya Su, Jianquan Liao, Juan Shen et autres

AIMS: Despite the tremendous improvement in therapeutic medication and intervention for coronary atherosclerotic disease (CAD), residual risks remain. Exome sequencing enables identification of rare variants and susceptibility genes for residual risks of early-onset coronary atherosclerotic disease (EOCAD) with well-controlled conventional risk factors. …

cn (code pays fourni par la source)

Incidence, survival, and prognostic nomogram of patients with small intestinal neuroendocrine tumors: A SEER population-based study

Yao Li Peng, Boqi Xu, Fan Zhang, Runda Wu et autres

Small intestinal neuroendocrine tumors (SI-NETs) are a group of rare and significantly heterogeneous tumors with limited research currently available. This study aimed to investigate the incidence, survival, and prognostic factors of SI-NETs. We selected data from the surveillance, epidemiology, and end results …

cn (code pays fourni par la source)

Abstract Tu105: Inhibition of Queuine tRNA-Ribosyltransferase 1 Ameliorates Heaptic Lipogenesis and Atherosclerosis

Runda Wu, shuning zhang, Yuanji ma, Wei Gao et autres

Background: Atherosclerosis threatens cardiovascular health, which is featured by abnormal lipid metabolism and chronic inflammation in arterial wall. Queuine tRNA-Ribosyltransferase 1 (QTRT1) , is an enzyme responsible for tRNA modification at the wobble base. Research Questions: It is unclear whether the function …

cn (code pays fourni par la source)

Preoperative contributing factors and the remission of diabetes after metabolic surgery: the mediating role of preoperative triglyceride

Lijuan Niu, Liqian Mu, Runda Wu, Shan Tong et autres

BACKGROUND AND OBJECTIVE: Limited understanding exists regarding the factors affecting the prognosis of surgical treatment for type 2 diabetes mellitus (T2DM), particularly in Chinese patients. In this study, we examined a cohort of early and intermediate obese T2DM patients to explore the …

cn (code pays fourni par la source)

Survival and Prognosis for Patients with Rectal Melanomas in the United States: A SEER-Based Study

Fan Zhang, Boqi Xu, Yao Peng, Runda Wu et autres

PURPOSE: Limited attention was paid to focus on rectal melanomas (RM). This study aimed to evaluate the survival rate and prognostic factors of RM. METHODS: The data for patients with RM from Surveillance, Epidemiology, and End Results (SEER) database were used to …

cn (code pays fourni par la source)