Thomas Liman

Emotion recognition in patients with mild cognitive impairment: The role of face processing and emotional intelligence

R Mahadevan, Naomi Kristin Giesers, Thomas Liman, K. Witt et autres

Background Emotion recognition ability is essential for social cognition, enabling humans to interpret and respond to emotion-related cues. However, so far, it is not known how underlying cognitive deficits, face processing and emotional intelligence are associated with emotion recognition, particularly in patients …

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Facial Emotion Recognition of Sadness Relates to Superior Parietal Cortical Thickness in Mild Cognitive Impairment

R Mahadevan, Naomi K. Giesers, Thomas Liman, Karsten Witt et autres

Mild cognitive impairment (MCI) is associated with early, regionally selective neurodegenerative changes that may affect socioemotional functioning before atrophy becomes widespread. This study examined whether structural brain alterations in MCI relate to facial emotion recognition performance. Sixty adults (30 MCI, 30 healthy …

Facial Emotion Recognition of Sadness Relates to Superior Parietal Cortical Thickness in Mild Cognitive Impairment

Mandy Roheger, Stephanie Rosemann, Andrea Hildebrandt, R Mahadevan et autres

Mild cognitive impairment (MCI) is associated with early, regionally selective neurodegenerative changes that may affect socioemotional functioning before atrophy becomes widespread. This study examined whether structural brain alterations in MCI relate to facial emotion recognition performance. Sixty adults (30 MCI, 30 healthy …

Brain-derived tau for monitoring brain injury in acute ischemic stroke

Naomi Vlegels, Nicoló Luca Knuth, Konstantin A. Steiner, Linjie Zhang et autres

A specific and accurate blood test for acute brain injury could help monitor infarct growth in ischemic stroke and serve as a surrogate end point in clinical trials. Using a single-molecule detection assay, we assessed plasma brain-derived tau (BD-tau), a marker selectively …

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Radar Multiple Bin Selection for Breathing and Heart Rate Monitoring in Acute Stroke Patients in a Clinical Setting

Benedek Szmola, Lars Hornig, Jan P. Vox, Thomas Liman et autres

Simple to use and accurate monitoring of stroke patients' breathing and heart rate in sleep is needed to lower the risk of secondary strokes and prevent worse functional outcomes due to disturbed sleep. In this study, we computed breathing and heart rates …

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Safety, Technical and Clinical Success of the Aperio Hybrid Thrombectomy Device in Acute Ischemic Stroke, a Prospective Post-market Clinical Follow-up Study (HYBRID)

Claudia Klüner, Benedikt Sundermann, Catalin George Iacoban, Daniel Behme et autres

PURPOSE: thrombectomy device (AHD) in routine clinical use. METHODS: We conducted a prospectively monitored, multicenter, national registry study with single-arm data collection including patients with acute intracranial vessel occlusion (anterior and posterior circulation, including medium vessel occlusions) who were treated with the …

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Effect of Mobile Stroke Unit Dispatch on Process Parameters and Functional Outcomes in Patients With Acute Stroke

Jessica L. Rohmann, Marco Piccininni, Martin Ebinger, Matthias Wendt et autres

BACKGROUND AND OBJECTIVES: Prehospital stroke management on mobile stroke units (MSUs) shortens time to IV thrombolysis (IVT) and improves functional outcomes. Because IVT effects are time-dependent, optimizing workflows and dispatch-related processes may enhance MSU benefits. The B_PROUD-2.0 study aimed to determine the …

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Associations of Soluble Inflammatory and Endothelial Activation Biomarkers with Cognitive Function Over Three Years After Ischemic Stroke—PROSCIS-B

Naomi K. Giesers, V Schaeff, Karen Gertz, Matthias Endres et autres

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Negative Emotion Recognition Impairments Despite Preserved Neural Activity in Patients with Mild Cognitive Impairment (MCI)

R Mahadevan, Naomi K. Giesers, Thomas Liman, Karsten Witt et autres

Being able to interpret emotional expressions is fundamental to social interaction. Although deficits in emotion recognition are well-documented in dementia, they have received less attention in mild cognitive impairment (MCI). Due to the overlap in neural processes supporting emotion and cognition, early …

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Risk factors for dementia and cognitive impairment within 5 years after stroke: a prospective multicentre cohort study

Jule Filler, Marios K. Georgakis, Daniel Janowitz, Marco Duering et autres

Background: Stroke survivors frequently experience subsequent cognitive impairment or dementia. We aimed to identify risk factors for post-stroke dementia (PSD) and cognitive impairment (PSCI) within 5 years after stroke. Methods: The DEMDAS (German Center for Neurological Diseases (DZNE) mechanisms of dementia after …

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Circulating cytokine levels and 5-year vascular recurrence after stroke: A multicenter prospective cohort study

Lanyue Zhang, Mohamad Ali Antabi, Omar El Bounkari, Rong Fang et autres

BACKGROUND AND OBJECTIVES: Anti-inflammatory therapies are tested in randomized trials for secondary stroke prevention. Detecting inflammatory biomarkers that predict vascular recurrence could optimize patient selection for these trials. METHODS: In a multicenter prospective cohort study, we measured plasma levels of 22 inflammatory …

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Lesion-Network Mapping of Poststroke Depressive Symptoms: Evidence From Two Prospective Ischemic Stroke Cohorts

Ana Sofía Ríos, Uchralt Temuulen, Ahmed A. Khalil, Kersten Villringer et autres

BACKGROUND: Poststroke depression affects up to one-third of stroke survivors, significantly impacting recovery and quality of life. However, its pathophysiology remains unclear. METHODS: We analyzed 2 independent, prospective ischemic stroke cohorts (PROSCIS-B [Prospective Cohort of Incident Stroke Berlin] and BAPTISe [Biomarkers and …

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