Tusneem Ahmed M. Elhassan

Systematic review and meta-analysis of AI methods for immature WBC subtype classification

Tusneem Ahmed M. Elhassan, Mohd Shafry Mohd Rahim, Fatin A. Elhaj, Alfadil Haroon et autres

Background: Automated morphology using computer vision and machine learning may support classification of immature leukocyte subtypes in acute myeloid leukemia (AML), but reported performance varies across studies and cell types. We systematically synthesized evidence on image-level classification of erythroblasts (EBO), monoblasts (MOB), …

Excellent outcomes using a novel reduced intensity conditioning with thiotepa and post-transplant cyclophosphamide for HLA-matched related donor transplant in adolescents and adults with sickle cell disease

Reem Alasbali, Mohsen Alzahrani, Karina Wilkerson, Phavina A Akhom et autres

sa, us, gb (code pays fourni par la source)

Prognostic significance of PNH clones in aplastic anemia treated with immunosuppression or allogeneic HSCT: a 20-year single-center experience

Alfadil Haroon, Hazzaa Abdulla Alzahrani, M Ismail Saleh, Ali Aalahmari et autres

BACKGROUND: Paroxysmal nocturnal hemoglobinuria (PNH) clones are detected in up to 60% of patients with aplastic anemia (AA); however, their prognostic impact remains incompletely defined, particularly in the context of frontline immunosuppressive therapy (IST) or allogeneic hematopoietic stem cell transplantation (HSCT). METHODS: …

sa, Égypte (code pays fourni par la source)

Real-world outcomes of Axicabtagene Ciloleucel CAR-T therapy in large B-cell lymphoma: a single-center observational study

Khalid Alsuhaibani, Amal Hamza Hejab, Maha J. Aljasser, Tusneem Ahmed M. Elhassan et autres

BACKGROUND: Axicabtagene Ciloleucel (Axi-cel) has recently transformed the treatment landscape for relapsed or refractory large B-cell lymphoma (R/R LBCL). Despite promising results in pivotal trials like ZUMA-1 and ZUMA-7, there is limited data on its outcomes in the Middle East and North …

sa (code pays fourni par la source)

International testing and refinement of AI algorithms predicting acute leukemia subtypes from routine laboratory data

A. T. Turki, Yi Fan, Alberto Hernandez-Sanchez, Wellington F. Silva et autres

Despite advances for patients with acute leukemia health disparities limit access to diagnosis and treatment. Artificial Intelligence (AI) approaches may address some disparities. We retrospectively assemble a diverse, international cohort of 6206 leukemia patients from 20 centers to test an AI tool …

de, cn, es, br, au, tr, nl, us, pl, sa, it, ar, in, Madagascar, gb (code pays fourni par la source)

Characteristic and Clinical Outcomes of Localized Gastric Cancer: A Real-World Experience

Amal Aljuhani, Mohamed Aseafan, Ali Mustafa Sheikh, Ali M. Alhanash et autres

BACKGROUND AND OBJECTIVE: Gastric and gastroesophageal junction (G/GEJ) cancers, with their poor prognosis, pose management challenges. Treatments like perioperative chemotherapy, neoadjuvant chemoradiotherapy, and adjuvant chemotherapy aim to improve outcomes. The 5-fluorouracil, leucovorin, oxaliplatin, docetaxel (FLOT) regimen has shown promise in enhancing survival. …

sa (code pays fourni par la source)

Salvage Therapy for Relapsed/Refractory Testicular Germ Cell Tumors: King Faisal Hospital and Research Center, Riyadh Experience

Muhammad Shahzad Rauf, Hazza A AlZahrani, Ali M. Alhanash, Fahad A. Almugbel et autres

Purpose: Optimal salvage treatment for relapsed/refractory germ cell tumors in men remains controversial. The options include conventional-dose chemotherapy (CDCT) and high-dose chemotherapy with autologous stem cell transplantation (HDCT-ASCT). There is currently a lack of data from the Middle East on this topic. …

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Transplant outcomes in adolescents and young adults with Philadelphia‐positive B‐cell acute lymphoblastic leukaemia

Manar Aleid, Riad El Fakih, Amr S. Hanbali, Feras Alfraih et autres

The data supporting this study's findings are available in the materials of this article. Data S1. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) …

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Combined Prophylactic HIPEC/IORT Versus Surgery Alone in Localized Gastric Cancer: A 14‑Year Real-World Experience From a Tertiary Center

Hadeel Elwaheidi, Ali Sheikh, Amal Aljuhani, Mohamed Aseafan et autres

sa (code pays fourni par la source)

Docetaxel versus androgen receptor pathway inhibitors as first-line therapy for metastatic castration-resistant prostate cancer after doublet therapy: a multicenter retrospective study from Saudi Arabia

Shouki Bazarbashi, Ahmed Abdelmotal, Tarek Ziad Arabi, Waleed Fallatah et autres

BACKGROUND: The management of metastatic castration-resistant prostate cancer (mCRPC) following progression on androgen deprivation therapy (ADT) combined with androgen receptor pathway inhibitors (ARPI) in the castration-sensitive (CS) setting remains unclear. Limited data exist comparing the efficacy of ARPI versus docetaxel as first-line …

sa, Égypte (code pays fourni par la source)

Prognostic significance of PNH clones in aplastic anemia treated with immunosuppression or allogeneic HSCT

Alfadil Haroon, Riad Omar El Fakih, Shaykhah Alotaibi, Ahmed Bin Salman et autres

Abstract Background: Aplastic anemia (AA) is a type of bone marrow failure caused by immune-mediated destruction of hematopoietic stem cells. Paroxysmal Nocturnal Hemoglobinuria clone (PNH) is often associated with AA (50%–60% of cases). The treatment of AA depends on the disease severity, …

sa (code pays fourni par la source)

Assessment of the medical oncology workforce in Saudi Arabia: Current state and future projections.

Abdulrahman Alfahadi, Shouki N. Bazarbashi, Tusneem Ahmed M. Elhassan, Sabah Alaklabi

289 Background: Medical oncologists play the primary role in the diagnosis, treatment, and management of cancer patients. Ensuring an adequate and well-trained medical oncology workforce is essential to meet the increasing demand for oncology services given the rapid increase in incidence of …

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