PRIMED: predicting DNA binding residues by leveraging pre-trained protein language models
Luoshu Zhang, Xin Li, Ruocen Song, Qianqian Song et autres
0 citationsFrontiers in Artificial Intelligence
Xiao Fan
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52Publications signalées
1689Citations signalées
1Affiliations récentes
Institutions déclarées
Domaines associés
Genomics and Rare DiseasesProtein Structure and DynamicsEpigenetics and DNA MethylationNutrition, Genetics, and DiseaseGenetic Associations and Epidemiology
Publications récentes
Genetic Compensation Restores Embryonic Viability in Fatty Acid Synthase Mutants
Yooseong Wang, Milagros Rincon Paz, Xiao Fan, Harold E. Smith et autres
0 citationsbioRxiv (Cold Spring Harbor Laboratory)
Structural basis for the assembly and modulation of human M-channels
F. X. Lu, Xiaoshuang Huang, Yuzhen Xie, Jian Huang et autres
0 citationsVita
Identification of Novel Susceptibility Genes for Early-Onset Colorectal Cancer Through Germline Rare Variant Burden Testing
Ruocen Song, Reger R. Mikaeel, Zhongping He, Mehgan Horsnell et autres
0 citationsCancers
Pediatric cardiomyopathy illustrates the importance of reinterpreting the significance of genetic variants
Teresa M. Lee, Erin Miller, Arthi Sridhar, Xiao Fan et autres
2 citationsProgress in Pediatric Cardiology
Cryo-EM Structure of HRSL Domain Reveals Activating Crossed Helices at the Core of GCN2
Kristina Solorio-Kirpichyan, Xiao Fan, Dmitrij Golovenko, А.A. Коростелев et autres
0 citationsbioRxiv (Cold Spring Harbor Laboratory)
The solution structure of human leptin reveals a conformational plasticity important for receptor recognition
Xiao Fan, Ruiqi Qin, Wensu Yuan, Jing‐Song Fan et autres
3 citationsStructure
Chemical shift assignments of wildtype human leptin
Xiao Fan, Ruiqi Qin, Wensu Yuan, Jing‐Song Fan et autres
1 citationBiomolecular NMR Assignments
Recent progress in leptin signaling from a structural perspective and its implications for diseases
Xiao Fan, Wensu Yuan, Weidong Huang, Zhi Lin
18 citationsBiochimie
SHINE: protein language model-based pathogenicity prediction for short inframe insertion and deletion variants
Xiao Fan, Hongbing Pan, Alan Tian, Wendy K. Chung et autres
11 citationsBriefings in Bioinformatics
Predicting functional effect of missense variants using graph attention neural networks
Haicang Zhang, Michelle S. Xu, Xiao Fan, Wendy K. Chung et autres
101 citationsNature Machine Intelligence
Clinical, neuroimaging and molecular characteristics of PPP2R5D-related neurodevelopmental disorders: an expanded series with functional characterisation and genotype–phenotype analysis
Nora Oyama, Pieter Vaneynde, Sara Reynhout, Emily M Pao et autres
32 citationsJournal of Medical Genetics
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