George Ofori‐Amanfo

Assessing Maternal Breastfeeding Plans and Perceived Barriers to Optimal Breastfeeding in Kumasi, Ghana

Adwoa A. Baffoe‐Bonnie, Sharla Rent, George Ofori‐Amanfo, John Adabie Appiah et autres

INTRODUCTION: Despite overwhelming evidence of the benefits of breastfeeding (BF) and its potential to decrease infant mortality, BF rates are low in many low- and middle-income countries like Ghana. We sought to assess Ghanaian mothers' BF plans and their rationale for these …

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Extracorporeal membrane oxygenation: a bridge to palliation in single ventricle physiology

Ivana Capin, George Ofori‐Amanfo, María Esperanza, Raghav Murthy et autres

Abstract Objective: To evaluate the outcomes of patients with single ventricle physiology supported with extracorporeal membrane oxygenation as a bridge to first-stage palliation. Methods: This was a retrospective registry-based study. Data from the Extracorporeal Life Support Organization registry were used to identify …

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Mapping Systemic Inflammation and Antibody Responses in Multisystem Inflammatory Syndrome in Children (MIS-C)

Conor Gruber, Roosheel S. Patel, Rebecca Trachtman, Lauren Lepow et autres

Molecular states during acute COVID-19 reveal distinct etiologies of long-term sequelae

Ryan C. Thompson, Nicole W. Simons, Lillian Wilkins, Esther Cheng et autres

Post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are debilitating, clinically heterogeneous and of unknown molecular etiology. A transcriptome-wide investigation was performed in 165 acutely infected hospitalized individuals who were followed clinically into the post-acute period. Distinct gene expression …

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The dynamic changes and sex differences of 147 immune-related proteins during acute COVID-19 in 580 individuals

Guillaume Butler‐Laporte, Edgar Gonzalez‐Kozlova, Chen‐Yang Su, Sirui Zhou et autres

INTRODUCTION: Severe COVID-19 leads to important changes in circulating immune-related proteins. To date it has been difficult to understand their temporal relationship and identify cytokines that are drivers of severe COVID-19 outcomes and underlie differences in outcomes between sexes. Here, we measured …

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34: EXTRACORPOREAL MEMBRANE OXYGENATION SUPPORT: A BRIDGE TO PALLIATION IN SINGLE-VENTRICLE PHYSIOLOGY

Ivana Capin, George Ofori‐Amanfo, María Esperanza, Raghav Murthy et autres

Capin, Ivana1; Ofori-Amanfo, George2; Esperanza, Maria2; Murthy, Raghav1; Oldenburg, Gary3; Glotzbach, Kristi4; Aydin, Scott5 Author Information

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Downregulation of exhausted cytotoxic T cells in gene expression networks of multisystem inflammatory syndrome in children

Noam D. Beckmann, Phillip Comella, Esther Cheng, Lauren Lepow et autres

Abstract Multisystem inflammatory syndrome in children (MIS-C) presents with fever, inflammation and pathology of multiple organs in individuals under 21 years of age in the weeks following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Although an autoimmune pathogenesis has been proposed, …

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Finding a Path to Better Sepsis Outcomes in Critical Care Ultrasound, One Step at a Time*

Erik Su, Saúl Flores, George Ofori‐Amanfo

1 Division of Critical Care Medicine, Department of Pediatrics, McGovern Medical School, Houston, TX 2 Section of Critical Care Medicine, Department of Pediatrics, Texas Children’s Hospital, Houston, TX 3 Division of Critical Care Medicine, Department of Pediatrics, Icahn School of Medicine at …

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Acute Kidney Injury Following Pediatric Liver Transplant

Layne Silver, Stephanie Pan, John C. Bucuvalas, Jessica Reid‐Adam et autres

OBJECTIVE: To determine the incidence, severity, and risk factors of postoperative acute kidney injury in pediatric liver transplant patients with and without inborn errors of metabolism. DESIGN: Retrospective cohort study. SETTING: Single-center PICU. PATIENTS: All children less than or equal to 18 …

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Volumetric Capnography in Pediatric Extracorporeal Membrane Oxygenation: A Case Series

Kim R. Derespina, Shivanand Medar, Scott I. Aydin, Shubhi Kaushik et autres

Abstract The kinetics of carbon dioxide elimination (VCO2) may be used as a surrogate for pulmonary blood flow. As such, we can apply a novel use of volumetric capnography to assess hemodynamic stability in patients requiring extracorporeal membrane oxygenation (ECMO). We report …

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Mapping Systemic Inflammation and Antibody Responses in Multisystem Inflammatory Syndrome in Children (MIS-C)

Conor Gruber, Roosheel S. Patel, Rebecca Trachtman, Lauren Lepow et autres

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ECMO support in SARS-CoV2 multisystem inflammatory syndrome in children in a child

Shubhi Kaushik, Neha Ahluwalia, Sandeep Gangadharan, Maria Esperenza et autres

In this report, we describe the case of a 5-year-old male with SARS-CoV-2 associated MIS-C with progressive respiratory failure and vasoplegic shock requiring extracorporeal support. At presentation, reverse transcription-polymerase chain reaction (RT-PCR) testing for SARS-CoV-2 was negative, however, SARS-CoV2 antibody testing was …

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