Sofia Roero

Castor oil plus sweeping membrane maneuver versus oral Misoprostol for labor induction: a prospective observational study

Francesca Ciabatti, Alessia Marzero, Eleonora Massicci, Laura Moretti et autres

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Multifetal Pregnancies in Women with CKD

Matteo Gianferrari, Rossella Attini, Sofia Roero, Costanza Valentini et autres

KEY POINTS: CKD carries an increased risk for developing hypertensive disorders of pregnancy in multifetal pregnancies. CKD in multifetal pregnancies is associated with a shorter duration of gestation and an increased risk of having a baby small for gestational age. Multifetal pregnancies …

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Perinatal outcomes of monochorionic monoamniotic twin pregnancies

Sofia Roero, Silvana Arduino, Agata Ingala, Chiara Peila et autres

OBJECTIVES: To describe the risk of early and late fetal loss of a cohort of monochorionic monoamniotic (MCMA) twin pregnancies; secondary objectives are to describe perinatal outcomes of these pregnancies and to identify which obstetric variables mostly influence the incidence of neonatal …

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Management of Monochorionic Twin Pregnancies Complicated by Selective Fetal Growth Restriction: Retrospective Single-Center 12-Year Experience

Sofia Roero, Silvana Arduino, Agata Ingala, Carlotta Bossotti et autres

Objectives: To describe the perinatal outcomes of a series of monochorionic diamniotic (MCDA) twin pregnancies complicated by selective fetal growth restriction (sFGR), classified according to the umbilical artery (UA) Doppler flow pattern of the smaller twin, and managed in a single centre …

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Effects of Homocysteine Circulating Levels on Human Spontaneous Fertility and In Vitro Fertilization Outcomes: A Literature Review

Alberto Revelli, Anna Maria Nuzzo, Laura Moretti, Silvana Arduino et autres

Background: Homocysteine (Hcy) plays a pivotal role in human reproduction, influencing gamete quality, embryo development, implantation, and pregnancy outcomes. It is central to folate and methionine metabolism and supports methylation-dependent epigenetic processes. Hyperhomocysteinemia (HHcy) exerts diverse biological effects and is associated with …

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Amniocentesis and Risk of Fetal Loss in Dichorionic‐Diamniotic Twin Pregnancy: A Case‐Control Study

Sofia Roero, Agata Ingala, Silvana Arduino, Carlotta Bossotti et autres

OBJECTIVE: There is a paucity of data regarding the risk of fetal loss due to invasive prenatal diagnosis in twins. The aim of the present study is to assess the rate of amniocentesis-related fetal loss in uncomplicated dichorionic-diamniotic (DCDA) twin pregnancies. METHODS: …

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Lysteria Monocytogenes Infection during Monochorionic Twin Pregnancy: Case Report and Review of the Literature

Sofia Roero, Chiara Peila, Silvana Arduino, Sonia Deantoni et autres

(LM), a small facultative intracellular bacillus. When occurring in pregnant women, it can be vertically transmitted to the fetus and the newborn. Infected women usually display aspecific and mild symptoms, and rarely develop the severe forms of the disease (such as neurolisteriosis). …

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Low-dose aspirin in the prevention of preeclampsia in twin pregnancy

Sofia Roero, Silvana Arduino, Isabella Ferrando, Arianna Arese et autres

Objective.To identify risk factors for hypertensive disorders of pregnancy (HDP) in multiple gestations and to evaluate the effectiveness of low dose aspirin administration in preventing HDP in a large cohort of multiple pregnancies.

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Maternal Circulating Vitamin D Level, Targeted Supplementation, and Perinatal Outcomes in Twin Pregnancy

Sofia Roero, Agata Ingala, Silvana Arduino, Miriam Folino Gallo et autres

BACKGROUND: Vitamin D deficiency is associated with several obstetric complications in singleton pregnancy. The aim of this study was to assess whether vitamin D levels affect the outcomes of twin pregnancy and if targeted supplementation can improve perinatal outcomes. METHODS: The serum …

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Is the Early Screening of Lower Genital Tract Infections Useful in Preventing Adverse Obstetrical Outcomes in Twin Pregnancy?

Sofia Roero, Giulia Benedetto, Lorena Charrier, Agata Ingala et autres

Objectives: Twin pregnancy implies a higher risk of preterm birth and, consequently, higher neonatal morbidity and mortality. In singleton pregnancies, infections of the lower genital tract (LGTIs) and bacterial vaginosis are associated with preterm labor, and their early detection has been proven …

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Retrospective comparison of monochorionic diamniotic twin pregnancies stratified by spontaneous or artificial conception

Sofia Roero, Silvana Arduino, Arianna Arese, Teresa Fea et autres

OBJECTIVES: fertilization (IVF) vs. spontaneously conceived counterparts. METHODS: Retrospective comparison. Data about MCDA twin pregnancies, conceived spontaneously or by IVF, attending the Twin Pregnancy Care Unit of Sant'Anna Hospital in Turin (Italy) between January 1st 2010 and March 31st 2022, were collected …

Gestational Diabetes Mellitus Does Not Worsen Obstetrical and Neonatal Outcomes of Twin Pregnancy

Alice Ronco, Sofia Roero, Silvana Arduino, Arianna Arese et autres

The specific effects of gestational diabetes mellitus (GDM) on twin pregnancy outcomes, which are at high risk per se, are unclear. The present study analyzes outcomes of twin pregnancies complicated by GDM (n = 227) by comparing them with GDM singleton pregnancies …

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