А. М. Мамбетова

The role of sclerostin in the formation of cardiovascular calcifi cation in chronic kidney disease C5D

A. T. Makhieva, А. М. Мамбетова

THE AIM: to study the relationship of blood sclerostin with clinical parameters and its influence on the probability of detection of cardiovascular calcification in patients with CKD C5D. PATIENTS AND METHODS. The study was a single-stage, cohort study involving 84 patients with …

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Systemic inflammation factors influence on the risk of detecting signs of cardiovascular calcification in a patient with stage 5D chronic kidney disease

А. М. Мамбетова, M. H. Hutueva, I. K. Thabisimova

BACKGROUND. Chronic kidney disease (CKD) is a common pathology influencing mortality risk in the world population. Calcification of aorta and heart structures (valves, coronary arteries) is a risk factor for cardiovascular complications. The influence of cytokines, integrin proinflammatory indices, acute phase proteins …

ru (code pays fourni par la source)

Fetuin A is assessing of developing bone mineral disorders and cardiovascular calcifi cation formation risk marker in patients with stage 5 chronic kidney disease

A. T. Makhieva, А. М. Мамбетова

INTRODUCTION. Recent years clinical studies have shown that bone mineral disorders in chronic kidney disease (CKD) increase the risk of cardiovascular mortality . Factors involved in mineral metabolism , dysregulation of the synthesis of which increases the risk of cardiovascular calcification in …

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Approaches to predicting the risk of acute cerebrovascular accident in patients with stage 5 chronic kidney disease and bone mineral disorders

А. М. Мамбетова, Sh. N. Gutarаeva, I. L. Semyonova

BACKGROUND. Among the causes of death in patients with chronic kidney disease (CKD) on dialysis, cardiovascular complications play a leading role. One of them is acute incidences of cerebral circulation (AICC). The assessment of the impact of mineral and bone disorders on …

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Evaluation of the level of natriuretic peptides in the diagnosis and characterization of chronic kidney disease and cardiorenal syndrome in children

А. М. Мамбетова, D. V. Bizheva, I. K. Thabisimova

BACKGROUND. Natriuretic peptides have cardio- and renoprotective effects, inhibiting inflammatory and proliferative processes. The role of natriuretic peptides in the early diagnosis and characterization of chronic kidney disease (CKD) and cardiovascular complications as the disease development and progresses has not been studied. …

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Possibilities of predicting the risk of cardiorenal syndrome in patients with chronic kidney disease on the background of congenital malformations of the urinary system

А. М. Мамбетова, D. V. Вizheva, M. K. Mokayeva, A. L. Nagatsyeva

BACKGROUND. Currently, there is no doubt that there is a close relationship between the condition of the kidneys and the cardiovascular system. Neurohormonal systems various parts long-term hyperactivation is important in the development of pathological processes. Natriuretic peptides provide cardio and renoprotective …

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Unsolved diagnostic issues of hypophosphatasia: Expert Council

E.Yu. Zakharova, Tatyana V. Varlamova, Sergey V. Voronin, N. Yu. Vlasenko et autres

Hypophosphatasia (HPP) is a rare hereditary metabolic disease resulting from the loss-of-function mutation in the ALPL gene encoding tissue-nonspecific alkaline phosphatase (ALP). Clinical presentations are polymorphic and manifest themselves differently depending on the age of disease onset and severity. The occurrence of …

Practical Significance of Inflammatory Markers for Infectious Secretary Diarrhea in Children

M. Bedelbaev, Z.K. Dzholbunova, E. Khalupko, А. М. Мамбетова

In this article, the practical significance of determining markers of inflammation (blood procalcitonin, fecal calprotectin, fecal lactoferrin) for distinguishing infectious secretory from infectious invasive diarrhea, as well as from functional diarrhea of non-infectious genesis, is given in the article. A survey was …

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Clinical and Epidemiological Characteristics of Parvoviral Infection (B-19) in Kyrgyz Republic

Svetlana Chechetova, E. Khalupko, R.M. Kadyrova, Z.K. Dzholbunova et autres

The paper presents the clinical and epidemiological characteristics of parvovirus infection (B-19) in Kyrgyzstan at the present stage. The main epidemiological factors identified in the process of collecting anamnesis are considered. The most typical clinical manifestations for this infection were also identified

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Interrelation between ofsystemic inflammation factors and cardiovascular calcification factors in patients of chronic kidney disease 5D stage

А. М. Мамбетова, M. H. Hutueva, I. K. Thabisimova, A. S. Kegaduyev

BACKGROUND. The role of inflammation and uremic intoxication in the development and progression of bone mineral dis­orders, including cardiovascular calcification, has been actively studied over the past decades. PATIENTS AND METHODS. A single-stage, cohort study of 85 patients with stage 5D CKD …

ru (code pays fourni par la source)

Predicting the risk of severe myocardial infarction in patientswith chronic 5D-stage kidneydisease and mineral-bone disorders

А. М. Мамбетова, Sh. N. Gutareva, I. L. Semyonova, A. Sh. Kegaduev

BACKGROUND. The increasing prevalence of chronic kidney disease is a global trend as well in general as in terminal kidney failure in particular. Of great interest is the analysis of the impact of mineral and bone disorders on the risk of cardiovascular …

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P039 National Cystic Fibrosis Patients Registry of Russia (RCFPR) from 2011–2018

E. Amelina, S. Krasovskiy, Elena Ivanovna Kondratieva, Nataliya Y. Kashirskaya et autres

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