Site-Specific Glycan Conjugation Improves Stability and Efficacy of an Antibody–Drug Conjugates Bearing DXd as a Cytotoxic Payload
Shino Manabe, Shogo Senga, Shogo Iwamoto, Hikaru Yarita et autres
2 citationsACS Omega
Ai Mitani
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9Publications signalées
101Citations signalées
1Affiliations récentes
Institutions déclarées
Domaines associés
Glycosylation and Glycoproteins ResearchEnzyme Production and CharacterizationCarbohydrate Chemistry and SynthesisLysosomal Storage Disorders ResearchMonoclonal and Polyclonal Antibodies Research
Publications récentes
N-glycan-modified α-L-iduronidase produced by transgenic silkworms ameliorates clinical signs in a Japanese macaque with mucopolysaccharidosis I
Chika Shinoda, Keisuke Kitakaze, Yuya Sasai, So-ichiro Nishioka et autres
4 citationsCommunications Medicine
Systematic Preparation of a 66-IgG Library with Symmetric and Asymmetric Homogeneous Glycans and Their Functional Evaluation
Shino Manabe, Shogo Iwamoto, Satoru Nagatoishi, Asako Hoshinoo et autres
14 citationsJournal of the American Chemical Society
N-glycan-modified α-L-iduronidase produced by transgenic silkworms ameliorates symptoms in a Japanese macaque with mucopolysaccharidosis I
Kohji Itoh, Chika Shinoda, Keisuke Kitakaze, Yuya Sasai et autres
0 citationsResearch Square
Characterization of novel endo-β-N-acetylglucosaminidases from intestinal Barnesiella intestinihominis that hydrolyze multi-branched complex-type N-glycans
Kanako Doi, Ai Mitani, Shin‐ichi Nakakita, Yujiro Higuchi et autres
6 citationsJournal of Bioscience and Bioengineering
Characterization of novel endo-β-N-acetylglucosaminidase from Bacteroides nordii that hydrolyzes multi-branched complex type N-glycans
Kristina Mae Bienes, Feunai Agape Papalii Tautau, Ai Mitani, Takashi Kinoshita et autres
9 citationsJournal of Bioscience and Bioengineering
Author Correction: Characterization of novel endo-β-N-acetylglucosaminidases from Sphingobacterium species, Beauveria bassiana and Cordyceps militaris that specifically hydrolyze fucose-containing oligosaccharides and human IgG
Yibo Huang, Yujiro Higuchi, Takashi Kinoshita, Ai Mitani et autres
1 citationScientific Reports
Characterization of Antibody Products Obtained through Enzymatic and Nonenzymatic Glycosylation Reactions with a Glycan Oxazoline and Preparation of a Homogeneous Antibody–Drug Conjugate via Fc N -Glycan
Shino Manabe, Yoshiki Yamaguchi, Kana Matsumoto, Hirobumi Fuchigami et autres
46 citationsBioconjugate Chemistry
Characterization of novel endo-β-N-acetylglucosaminidases from Sphingobacterium species, Beauveria bassiana and Cordyceps militaris that specifically hydrolyze fucose-containing oligosaccharides and human IgG
Yibo Huang, Yujiro Higuchi, Takashi Kinoshita, Ai Mitani et autres
19 citationsScientific Reports
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