Andrea Fleisch Marcus

Atopic dermatitis and ocular surface disorders: a United States claims-based cross-sectional study

Penny Asbell, Esen K. Akpek, Joseph F. Merola, Jacob P. Thyssen et autres

BACKGROUND: To estimate the prevalence of ocular surface disorders (OSDs) by atopic dermatitis (AD) status and evaluate healthcare resource utilization (HRU) among patients with AD. METHODS: Patients (all ages) enrolled in the Optum Clinformatics® database were included in this two-part, retrospective, observational, …

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Advancing Health Equity in Europe: Explore, Tailor, Implement, and Evaluate ( ETIE )—A Framework of Diversity and Fairness in Pharmacoepidemiologic Research

Enriqueta Vallejo‐Yagüe, Sieta T. de Vries, Daniel La Parra‐Casado, Helga Gardarsdóttir et autres

Pharmacoepidemiology should represent and benefit populations equitably, embracing diversity and equity, and ensuring fairness. This article describes equity and fairness in pharmacoepidemiology, depicts key diversity domains, and provides an operational framework and call for action to implement diversity and fairness in pharmacoepidemiologic …

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Incidence of Conjunctivitis and Keratitis Among Individuals with Moderate-to-Severe Atopic Dermatitis Treated with Dupilumab in the United States: a Cohort Study in Routine Care Based on Healthcare Claims

Jessica M. Franklin, Andrea Fleisch Marcus, Ihtisham Sultan, Ashley N. Howell et autres

INTRODUCTION: In clinical trials of patients with atopic dermatitis (AD), conjunctivitis and keratitis occurred more frequently with dupilumab than placebo. Studies using real-world data have also shown a higher incidence with dupilumab but did not use validated algorithms to identify the population …

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Development and Validation of Claims‐Based Algorithms for Conjunctivitis and Keratitis

Andrea K. Chomistek, Jessica M. Franklin, Rachel E. Sobel, Andrea Fleisch Marcus et autres

BACKGROUND: Ocular surface disorders have been reported among patients with various medical conditions, including atopic dermatitis (AD). Nonetheless, validated algorithms to identify conjunctivitis and keratitis in claims data are lacking. OBJECTIVE: Develop validated, claims-based algorithms for conjunctivitis and keratitis among patients with …

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Commentary: Response to “Dupilumab therapy for atopic dermatitis is associated with increased risk of cutaneous T cell lymphoma: A retrospective cohort study”

Tien V. Nguyen, Andrea Fleisch Marcus, Sarah‐Jo Sinnott, Anna Coleman et autres

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53040 Rates of Viral Non-Respiratory Infections in Patients with Moderate-to-Severe Atopic Dermatitis in the US: A Retrospective Study of Administrative Claims

Vivian Y. Shi, Mark G. Kirchhof, David Oliveri, Xin Zhao et autres

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700 - Characterization of atopic dermatitis medication use before and during pregnancy in the United States

Laura E. Dodge, Shiyao Gao, Sarah‐Jo Sinnott, Andrea Fleisch Marcus et autres

Abstract Introduction & Objectives There are limited data on peri-partum use of atopic dermatitis (AD) therapies, including for dupilumab, the first AD biologic drug approved by the United States (US) Food and Drug Administration. We characterized AD medication (systemic therapy or phototherapy) …

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Application of multiple validated algorithms for identifying incident breast cancer among individuals with atopic dermatitis

Adriana Campos, Ramya Ramasubramanian, Cherise Wong, Andrea Fleisch Marcus

PURPOSE: Validated algorithms (VAs) in insurance claims databases are often used to estimate the prevalence and incidence of comorbidities and evaluate safety signals. However, although they are then used in different data sources or subpopulations from those in which they were developed …

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Association between allergic conditions and COVID-19 susceptibility and outcomes

Chao Chen, Xue Song, Dana J. Murdock, Andrea Fleisch Marcus et autres

BACKGROUND: The relationship between underlying type 2 inflammation and immune response to COVID-19 is unclear. OBJECTIVE: To assess the relationships between allergic conditions and COVID-19 susceptibility and outcomes. METHODS: In the Optum database, adult patients with and without major allergic conditions (asthma, …

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348 Development and validation of a claims-based algorithm for moderate-to-severe atopic dermatitis using U.S. real-world data

Andrea K. Chomistek, Jessica M. Franklin, Rachel E. Sobel, Andrea Fleisch Marcus et autres

Abstract Real-world data (RWD) source such as insurance claims data, provides the opportunity to draw on the experience of thousands of patients treated in routine clinical practice to better understand the relationships between exposures and outcomes. Nonetheless, conducting studies on atopic dermatitis …

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Is Nutrition Specific Quality of Life Associated With Nutritional Status?

Sarah Feasel-Aklilu, Andrea Fleisch Marcus, J. Scott Parrott, Emily Peters et autres

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Comparison of Calorie and Protein Intake of Very Low Birth Weight Infants Receiving Mother's Own Milk or Donor Milk When the Nutrient Composition of Human Milk Is Measured With a Breast Milk Analyzer

Melanie Newkirk, Fauzia Shakeel, Prabhu S. Parimi, Pamela Rothpletz‐Puglia et autres

BACKGROUND: In premature infants, donor breast milk (DBM) is assumed to provide reduced nutrients vs. mother's own milk (MOM). This study examined calorie and protein delivery when very low birth weight infants were fed fortified MOM or DBM, with a known nutrient …

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