Accès ouvert
2026
article
OpenAlex
Hanane Maghrebi, Greta Mucignat, Fatima Lakhdar, Bouchra Benhniya et autres
Introduction Within an integrative medicine approach that links veterinary and human health, red algae extracts are gaining attention as promising sources of natural bioactive compounds with potential anticancer properties. This study investigates the selectivity of Plocamium cartilagineum extract (PCE) against canine cancer …
it, Maroc
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Accès ouvert
2026
article
OpenAlex
Veronica Di Paolo, Francesco Maria Ferrari, Italo Poggesi, Mauro Dacasto et autres
Introduction: A genetic algorithm (GA)-based approach was designed to predict drug–drug interactions (DDIs) triggered by cytochrome P450 3A (CYP3A) inhibition or induction in horses. Methods: Area under the concentration-time curve ratios (AUCRs), obtained from published in vivo DDI studies in horses, were …
it, us
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Accès ouvert
2026
report
OpenAlex
Federica Tonolo, Sara Khazzar, Marta Castrica, Mucignat Greta et autres
This study was funded by the European Union - NextGenerationEU, in the framework of the iNEST - Interconnected Nord-Est Innovation Ecosystem (PNRR M4C211.5, iNEST ECS00000043, CUP C43C22000340006) The views and opinions expressed are solely those of the authors and do not necessarily …
it
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Accès ouvert
2026
report
OpenAlex
Federica Tonolo, Sara Khazzar, Marta Castrica, Mucignat Greta et autres
This study was funded by the European Union - NextGenerationEU, in the framework of the iNEST - Interconnected Nord-Est Innovation Ecosystem (PNRR M4C211.5, iNEST ECS00000043, CUP C43C22000340006) The views and opinions expressed are solely those of the authors and do not necessarily …
it
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Accès ouvert
2026
article
OpenAlex
Greta Mucignat, Ewa Dejnaka, Marianna Pauletto, Rosa Maria Lopparelli et autres
Introduction Olaparib (OLA) is a poly ADP-ribose polymerase inhibitor (PARPi) indicated for solid cancers harboring BRCA1/2 mutations. Recent evidences suggest that sensitivity to PARPis may also be influenced by other factors that impair the DNA repair mechanisms. Since various hematological malignancies exhibit …
it, pl, us
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Accès ouvert
2026
article
OpenAlex
Greta Mucignat, Davide Stefanutti, Marianna Pauletto, Edoardo Pietropoli et autres
BACKGROUND: Obesity is a well-known concern in pets that often poses challenges in terms of successful maintenance of weight loss after different types of interventions. Nutraceuticals could represent a promising strategy to handle this disease. Among them, Arthrospira platensis (Spirulina) is reported …
it
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Accès ouvert
2025
article
OpenAlex
Greta Mucignat, Fatima Lakhdar, Ewa Dejnaka, Lorena Lucatello et autres
Within the “One Health, One Medicine” and comparative oncology paradigms, algal extracts have attracted attention, containing natural compounds (NCs) with biological activities, including anti-cancer properties. To characterize the biological effects of a Sphaerococcus coronopifolius extract (SCE), two canine mastocytoma and two normal …
it, Maroc, pl, us
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Accès ouvert
2025
article
OpenAlex
Eylem Emek Akyürek, Joana G. P. Jacinto, Silvia Iori, Elisa Bianchini et autres
Brody myopathy is an ultra-rare autosomal recessive inherited disorder that impairs skeletal muscle function in humans. It is caused by deficiency of the Sarco(Endo)plasmic reticulum Ca2+-ATPase isoform1 (SERCA1), arising from defects, mainly missense mutations, in the ATP2A1 gene. At present, neither specific …
it, ch, us
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Accès ouvert
2025
article
OpenAlex
Anastasia Lisuzzo, Luca Spadotto, Michele Muraro, Sandro Mazzariol et autres
) contains more than 30 different toxic cardiac glycosides, including oleandrin. Intoxication can occur through ingestion or inhalation in several species, including cattle. A total of 76 of 205 beef cattle died within 30 h due to the burning of oleander mowing. …
it
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Accès ouvert
2025
article
OpenAlex
Marija Bošković, Marianna Pauletto, Mery Giantin, Mauro Dacasto et autres
BACKGROUND: Growth-related myopathies, including white striping (WS), wooden breast (WB), and spaghetti meat (SM), compromise broiler meat quality, causing significant economic losses. Although these myopathies share some histological features, their molecular mechanisms remain incompletely understood, particularly regarding sex-specific differences. This study aimed …
it, rs
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Accès ouvert
2025
review
OpenAlex
Denisa Pérez Gaudio, Mery Giantin, Marianna Pauletto, Mauro Dacasto
Introduction Thymol, a phenolic compound present in essential oils, has shown promising pharmacological properties and potential veterinary applications. This systematic review aims to evaluate the pharmacological and toxicological effects of thymol on animals. Materials and methods A comprehensive search following PRISMA 2020 …
ar, it
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Accès ouvert
2025
article
OpenAlex
Jayson Cagadas Pasaol, Ewa Dejnaka, Greta Mucignat, Joanna Bajzert et autres
BACKGROUND: The introduction of genetic tests based on next-generation sequencing techniques into veterinary cancer diagnostics provides information on molecularly targeted therapies useful for dogs. However, there is still a lack of in vitro studies describing the effect and mechanism of action of …
pl, it, us
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