Mehmet Aliustaoğlu

Effect of Music on Anxiety and Fatigue in Cancer Patients Undergoing Chemotherapy: A Randomized Controlled Trial

Havva Gezgin Yazıcı, Çiğdem Ökten, Esra Karabulut, Mehmet Aliustaoğlu

Background: Anxiety and fatigue are symptoms typically experienced by cancer patients undergoing chemotherapy. In dealing with these symptoms, listening to music may help patients. Methods: The randomized controlled study was conducted between May 1, 2022 and November 10, 2022 with 60 patients …

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Küçük Molekül Tirozin Kinaz İnhibitörleri; ALK Hedefli Tedaviler (Alektinib, Lorlatinib, Brigatinib)

Hatime Arzu Yaşar, Mehmet Aliustaoğlu

Hedgehog Yolağı İnhibitörleri (Vismodegib, Erismodegib)

Mustafa Başak, Mesut Şeker, Mehmet Aliustaoğlu

Tyrosine kinase inhibitors in the treatment of metastatic renal cell cancer patients with early cytokine intolerance: TURCOS, a Turkish national, prospective observational study

Mustafa Beneklı, Mahmut Gümüş, Metin Özkan, Faysal Dane et autres

OBJECTIVE: Cytokines have been the mainstay of treatment in metastatic renal cell cancer (mRCC) for decades before the introduction of tyrosine kinase inhibitors (TKIs), which dramatically changed the therapeutic landscape in these patients. This observational study was designed to evaluate use of …

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Efficacy and safety of bevacizumab in Turkish patients with metastatic and recurrent cervical cancer

Özlem Erçelep, Deniz Tataroğlu Özyükseler, Melike Özçelik, Heves Sürmeli et autres

OBJECTIVE: To evaluate the efficacy of bevacizumab a monoclonal, antivascular endothelial growth factor antibody in combination with cytotoxic chemotherapy in Turkish patients with recurrent and metastatic cervical cancer. MATERIALS AND METHODS: Data of 64 patients with metastatic or recurrent cervical cancer, receiving …

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Third-line Therapy for Metastatic Renal Cell Carcinoma and Its Effect on Quality of Life and Overall Survival: A National, Multicenter, Observational Study

İrfan Çiçin, Aydın Çiltaş, Saadettin Kılıçkap, Berna Öksüzoğlu et autres

ABS TRACT Objective:The study aimed to evaluate the efficacy of targeted therapies used as the third-line treatment after first-line cytokine and second-line tyrosine kinase inhibitor (TKI) therapies in metastatic renal cell carcinoma (mRCC) patients and assess the quality of life (QoL) of …

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PTK-7 Expression in Gastric Cancer: A Prognostic Determinant

Melike Özçelik, Özlem Erçelep, Sevinç Hallaç Keser, Nagehan Özdemir Barışık et autres

Background: Protein tyrosine kinase-7, a regulatory protein in the Wnt signaling pathway, was highly overexpressed in various cancer types and assumed to be related to prognosis. Aims: The purpose of this study is to assess whether protein tyrosine kinase-7 expression status in …

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Evaluation of The Relationship Between Glycaemic Regulation Parameters and Neutrophil-to-Lymphocyte Ratio in Type 2 Diabetic Patients

Seydahmet Akın, Zeki Aydın, Güven Yılmaz, Mehmet Aliustaoğlu et autres

Background: The neutrophil-to-lymphocyte ratio (NLR) is a simple and inexpensive examination that is considered to show inflammation. In this study, which included a control group, the authors aimed to investigate if there was a relationship between glycaemic regulation parameters and NLR in …

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Determination of Rank, Rankl and Opg Gene Polymorphisms in Triple-Negative Breast Cancer Patients and Invesgation of its Effect on Bone Metastasis

Şükran Yıldız, Hani Al Saadoni, Mehmet Aliustaoğlu, Arzu Ergen et autres

Objective: Triple negative breast cancer (TNBC) is a sub-type of breast cancer with the worst prognosis and highest risk of mortality. Bone metastasis is the most common metastasis type among women with breast cancer. RANK and OPG, are the members of the …

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Molecular subtypes are prognostic for N3 breast cancer patients in the modern therapeutic era

�zlem Yersal, Kaplan Ma, Abdurrahman Işıkdoğan, Nuriye �zdemir et autres

Nodal (N) status and molecular subtypes are well-known prognostic factors for breast cancer patients. The aim of the present study was to evaluate whether there was a prognostic role of molecular subtypes for pN3a breast cancer patients in the modern therapeutic era. …

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Clinical importance of discordance of hormone receptors and Her2/neu status after neoadjuvant chemotherapy in breast cancer.

Bala Başak Öven Ustaalıoğlu, Fugen Vardar, Ahmet Bılıcı, Günay Gürleyik et autres

PURPOSE: The aim of this study was to compare the hormone receptors' (HR) and HER2/neu status between core needle biopsy (CNB) and residual tumor after surgery of breast cancer treated with neoadjuvant chemotherapy (NAC), and also to evaluate the impact of discordance …

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Effectiveness and Safety of LMWH Treatment in Patients With Cancer Diagnosed With Non-High-Risk Venous Thromboembolism: Turkish Observational Study (TREBECA)

Ersin Özaslan, Metin Özkan, İrfan Çiçin, Mustafa Beneklı et autres

We compared the efficacy and safety of low-molecular-weight heparins (LMWHs) in patients with cancer who are at low risk of venous thromboembolism (VTE). Patients were treated by medical oncologists in Turkey at 15 sites, where they were enrolled and followed up for …

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