Pengpeng Lei

Targeting Activator Protein-1 Transcription Factor Subunit FOSL1-Mediated Cuproptosis Sensitizes Radioresistant Non-Small Cell Lung Cancer

Xiqian Zhuo, Yunfeng Li, Ling Qiu, Reyida Aishajiang et autres

Radiotherapy plays a pivotal role in the management of nonsmall-cell lung cancer (NSCLC), particularly for patients who are not candidates for surgical intervention. Despite its significance, the issue of radioresistance remains a substantial challenge in the treatment of the NSCLC. Therefore, it …

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Harnessing disulfidptosis-ferroptosis synergy to potentiate radiotherapy in triple-negative breast cancer

Yan Geng, Pengye Du, Reyida Aishajiang, Min Jiang et autres

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CCDC 2564703: Experimental Crystal Structure Determination

Ran An, Qishun Wang, Yuan Liang, Pengye Du et autres

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, …

CCDC 2564702: Experimental Crystal Structure Determination

Ran An, Qishun Wang, Yuan Liang, Pengye Du et autres

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, …

Rare-earth upconversion luminescence mediate mitochondrial endogenous calcium overload-induced pyroptosis for tumor immunotherapy

Shuyu Liu, Pengye Du, Jianhao Zheng, Pengpeng Lei et autres

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Pt-MOF nanozymes: synthesis strategies, catalytic mechanisms, and biosensing applications

Boyan Sun, Rundong Chen, Junjie Wang, Yikai Zhang et autres

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Phosphatase-like nanozyme induce disulfidptosis by interfering the pentose phosphate pathway and promote anti-tumor immunity

Yi Wei, Pengye Du, Shuyu Liu, Yan Geng et autres

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Near-infrared-II Ag-based quantum dots for fluorescence imaging

Kaimin Du, Liying Ma, Kun Liu, Pengpeng Lei et autres

Compared with traditional near-infrared-I (NIR-I, 700-900 nm) fluorescence imaging, near-infrared-II (NIR-II, 1000 - 1700 nm) fluorescence imaging has unique advantages such as lower background fluorescence, higher sensitivity, and the ability to achieve higher tissue penetration depth and spatial resolution in vivo imaging. …

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A General Synthesis Strategy for Alkali Metal Halide Nanosalts

Pengye Du, Pengpeng Lei, Jianhao Zheng, Shuyu Liu et autres

Nanosalts demonstrate enormous application prospects due to their unique combination of "inorganic salt" and "nano" properties, and their rapid development inevitably requires a rich toolbox of synthesis strategies and materials library. Herein, a general synthesis strategy for the construction of alkali metal …

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Biomimetic nanovaccines with self-adjuvant effects induced broad-spectrum neutralizing antibodies against SARS-CoV-2 infection in rodents

Pengye Du, Yongkun Zhao, Yuan Liang, Cheng Zhang et autres

The emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants seriously threatens the efficacy of current coronavirus disease 2019 (COVID-19) vaccines. Therefore, there is an urgent need to develop next-generation vaccine platforms capable of counteracting current and prospective viral variants. In this …

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NIR-mediated endosomal escape-enhanced STING-pyroptosis self-recycling amplification/FNAzymes cleavage for triple-negative breast cancer therapy

Yuan Liang, Ran An, Pengye Du, Shuyu Liu et autres

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Biodegradable Cesium Nanosalts Activating Antitumor Immunity via Inducing Cellular Pyroptosis and Interfering with Metabolism

Pengye Du, Pengpeng Lei, Jianhao Zheng, Yuan Liang et autres

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